Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control
Serra, Margarida, Brito, Catarina, Sousa, Marcos F.Q., Jensen, Janne, Tostões, Rui, Clemente, João, Strehl, Raimund, Hyllner, Johan, Carrondo, Manuel J.T., Alves, Paula M.
Published in Journal of biotechnology (02.08.2010)
Published in Journal of biotechnology (02.08.2010)
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Journal Article
Metabolic alterations induced by ischemia in primary cultures of astrocytes: merging ¹³C NMR spectroscopy and metabolic flux analysis
Amaral, Ana I, Teixeira, Ana P, Martens, Sanja, Bernal, Vicente, Sousa, Marcos F.Q, Alves, Paula M
Published in Journal of neurochemistry (01.05.2010)
Published in Journal of neurochemistry (01.05.2010)
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Journal Article
Integrating human stem cell expansion and neuronal differentiation in bioreactors
Serra, Margarida, Brito, Catarina, Costa, Eunice M, Sousa, Marcos F Q, Alves, Paula M
Published in BMC biotechnology (22.09.2009)
Published in BMC biotechnology (22.09.2009)
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Journal Article
Production of oncolytic adenovirus and human mesenchymal stem cells in a single-use, Vertical-Wheel bioreactor system: Impact of bioreactor design on performance of microcarrier-based cell culture processes
Sousa, Marcos F. Q., Silva, Marta M., Giroux, Daniel, Hashimura, Yas, Wesselschmidt, Robin, Lee, Brian, Roldão, António, Carrondo, Manuel J. T., Alves, Paula M., Serra, Margarida
Published in Biotechnology progress (01.11.2015)
Published in Biotechnology progress (01.11.2015)
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Exploring continuous and integrated strategies for the up- and downstream processing of human mesenchymal stem cells
Cunha, Bárbara, Aguiar, Tiago, Silva, Marta M., Silva, Ricardo J.S., Sousa, Marcos F.Q., Pineda, Earl, Peixoto, Cristina, Carrondo, Manuel J.T., Serra, Margarida, Alves, Paula M.
Published in Journal of biotechnology (10.11.2015)
Published in Journal of biotechnology (10.11.2015)
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Journal Article
A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening
Sousa, Bárbara B., Sousa, Marcos F. Q., C. Marques, Marta, Seixas, João D., Brito, José A., Matias, Pedro M., Bernardes, Gonçalo, Roldão, António
Published in Bioprocess and biosystems engineering (01.01.2021)
Published in Bioprocess and biosystems engineering (01.01.2021)
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Journal Article
Bioanalytics for Influenza Virus-Like Particle Characterization and Process Monitoring
Carvalho, Sofia B, Silva, Ricardo J S, Sousa, Marcos F Q, Peixoto, Cristina, Roldão, António, Carrondo, Manuel J T, Alves, Paula M
Published in Frontiers in bioengineering and biotechnology (18.02.2022)
Published in Frontiers in bioengineering and biotechnology (18.02.2022)
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Journal Article
Perfusion Stirred-Tank Bioreactors for 3D Differentiation of Human Neural Stem Cells
Simão, Daniel, Arez, Francisca, Terasso, Ana P, Pinto, Catarina, Sousa, Marcos F Q, Brito, Catarina, Alves, Paula M
Published in Methods in molecular biology (Clifton, N.J.) (2016)
Published in Methods in molecular biology (Clifton, N.J.) (2016)
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Towards purification of adenoviral vectors based on membrane technology
Peixoto, Cristina, Ferreira, Tiago B., Sousa, Marcos F. Q., Carrondo, Manuel J. T., Alves, Paula M.
Published in Biotechnology progress (01.11.2008)
Published in Biotechnology progress (01.11.2008)
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Journal Article
Robust Expansion of Human Pluripotent Stem Cells: Integration of Bioprocess Design With Transcriptomic and Metabolomic Characterization
Silva, Marta M., Rodrigues, Ana F., Correia, Cláudia, Sousa, Marcos F.Q., Brito, Catarina, Coroadinha, Ana S., Serra, Margarida, Alves, Paula M.
Published in Stem cells translational medicine (01.07.2015)
Published in Stem cells translational medicine (01.07.2015)
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Journal Article
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors
Seixas, João D., Sousa, Bárbara B., C. Marques, Marta, dos Santos Guerreiro, Ana Maria, Traquete, Rui, Rodrigues, Tiago, S. Albuquerque, Inês, Sousa, Marcos F. Q., Lemos, Ana R., Sousa, Pedro M. F., Bandeiras, Tiago M., Wu, Di, Doyle, Shelby K., Robinson, Carol V., Koehler, Angela N., Corzana, Francisco, Matias, Pedro M., Bernardes, Gonçalo
Published in RSC chemical biology (01.10.2020)
Published in RSC chemical biology (01.10.2020)
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Journal Article
Human amniocyte-derived cells are a promising cell host for adenoviral vector production under serum-free conditions
Silva, Ana Carina, Simão, Daniel, Küppers, Claudia, Lucas, Tanja, Sousa, Marcos F Q, Cruz, Pedro, Carrondo, Manuel J T, Kochanek, Stefan, Alves, Paula M
Published in Biotechnology journal (01.05.2015)
Published in Biotechnology journal (01.05.2015)
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Triple layered rotavirus VLP production: Kinetics of vector replication, mRNA stability and recombinant protein production
Vieira, Helena L.A., Estêvão, Catarina, Roldão, António, Peixoto, Cristina C., Sousa, Marcos F.Q., Cruz, Pedro E., Carrondo, Manuel J.T., Alves, Paula M.
Published in Journal of biotechnology (17.10.2005)
Published in Journal of biotechnology (17.10.2005)
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Journal Article
Conference Proceeding
Production of high‐quality SARS‐CoV‐2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance
Castro, Rute, Nobre, Lígia S., Eleutério, Rute P., Thomaz, Mónica, Pires, António, Monteiro, Sandra M., Mendes, Sónia, Gomes, Ricardo A., Clemente, João J., Sousa, Marcos F. Q., Pinto, Filipe, Silva, Ana C., Freitas, Micael C., Lemos, Ana R., Akpogheneta, Onome, Kosack, Lindsay, Bergman, Marie‐Louise, Duarte, Nadia, Matoso, Paula, Costa, Júlia, Bandeiras, Tiago M., Gomes‐Alves, Patricia, Gonçalves, Carlos P., Demengeot, Jocelyne, Alves, Paula M.
Published in Biotechnology and Bioengineering (01.06.2021)
Published in Biotechnology and Bioengineering (01.06.2021)
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Journal Article
Web Resource
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation
Simão, Daniel, Silva, Marta M., Terrasso, Ana P., Arez, Francisca, Sousa, Marcos F.Q., Mehrjardi, Narges Z., Šarić, Tomo, Gomes-Alves, Patrícia, Raimundo, Nuno, Alves, Paula M., Brito, Catarina
Published in Stem cell reports (14.08.2018)
Published in Stem cell reports (14.08.2018)
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Journal Article
Establishing Suspension Cell Cultures for Improved Manufacturing of Oncolytic Adenovirus
Moreira, Ana Sofia, Silva, Ana Carina, Sousa, Marcos F. Q., Hagner‐McWhirterc, Åsa, Ahlénc, Gustaf, Lundgren, Mats, Coroadinha, Ana S., Alves, Paula M., Peixoto, Cristina, Carrondo, Manuel J. T.
Published in Biotechnology journal (01.04.2020)
Published in Biotechnology journal (01.04.2020)
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Journal Article
Process development for the mass production of Ehrlichia ruminantium
Marcelino, Isabel, Sousa, Marcos F.Q., Veríssimo, Célia, Cunha, António E., Carrondo, Manuel J.T., Alves, Paula M.
Published in Vaccine (06.03.2006)
Published in Vaccine (06.03.2006)
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Journal Article
Establishing Liver Bioreactors for In Vitro Research
Rebelo, Sofia P, Costa, Rita, Sousa, Marcos F Q, Brito, Catarina, Alves, Paula M
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2015)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2015)
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