A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division
Amaral, Maiara, de Sousa, Fernanda S., Silva, Thais A. Costa, Junior, Andrés Jimenez G., Taniwaki, Noemi N., Johns, Deidre M., Lago, João Henrique G., Anderson, Edward A., Tempone, Andre G.
Published in Scientific reports (16.04.2019)
Published in Scientific reports (16.04.2019)
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Neuroprotective Effect of 3-[(4-Chlorophenyl)selanyl]-1-methyl-1H-indole on Hydrogen Peroxide-Induced Oxidative Stress in SH-SY5Y Cells
Casaril, Angela Maria, Segatto, Natália, Simões, Lucas, Paschoal, Júlia, Domingues, Micaela, Vieira, Beatriz, Sousa, Fernanda S. S., Lenardão, Eder João, Seixas, Fabiana K., Collares, Tiago, Savegnago, Lucielli
Published in Neurochemical research (01.03.2021)
Published in Neurochemical research (01.03.2021)
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Journal Article
Discovery of New Hits as Antitrypanosomal Agents by In Silico and In Vitro Assays Using Neolignan-Inspired Natural Products from Nectandra leucantha
Araujo, Sheila C., Sousa, Fernanda S., Costa-Silva, Thais A., Tempone, Andre G., Lago, João Henrique G., Honorio, Kathia M.
Published in Molecules (Basel, Switzerland) (06.07.2021)
Published in Molecules (Basel, Switzerland) (06.07.2021)
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Journal Article
Oncopig bladder cancer cells recapitulate human bladder cancer treatment responses in vitro
Segatto, Natália V, Simões, Lucas D, Bender, Camila B, Sousa, Fernanda S, Oliveira, Thais L, Paschoal, Júlia D F, Pacheco, Bruna S, Lopes, Isadora, Seixas, Fabiana K, Qazi, Aisha, Thomas, Faith M, Chaki, Sulalita, Robertson, Noah, Newsom, Jordan, Patel, Shovik, Rund, Laurie A, Jordan, Luke R, Bolt, Courtni, Schachtschneider, Kyle M, Schook, Lawrence B, Collares, Tiago V
Published in Frontiers in oncology (26.02.2024)
Published in Frontiers in oncology (26.02.2024)
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Journal Article
Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages
Grecco, Simone S., Costa-Silva, Thais A., Jerz, Gerold, de Sousa, Fernanda S., Londero, Vinicius S., Galuppo, Mariana K., Lima, Marta L., Neves, Bruno J., Andrade, Carolina H., Tempone, Andre G., Lago, João Henrique G.
Published in Chemico-biological interactions (01.11.2017)
Published in Chemico-biological interactions (01.11.2017)
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Neolignans isolated from twigs of Nectandra leucantha Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity
Grecco, Simone S, Costa-Silva, Thais A, Sousa, Fernanda S, Cargnelutti, Stefano B, Umehara, Eric, Mendonça, Poliana S, Tempone, Andre G, Lago, Joao Henrique G
Published in The journal of venomous animals and toxins including tropical diseases (27.09.2018)
Published in The journal of venomous animals and toxins including tropical diseases (27.09.2018)
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Chemical Structure and Localization of Levan, the Predominant Fructan Type in Underground Systems of Gomphrena marginata (Amaranthaceae)
Joaquim, Emanuela O, Hayashi, Adriana H, Torres, Luce M B, Figueiredo-Ribeiro, Rita C L, Shiomi, Norio, de Sousa, Fernanda S, Lago, João H G, Carvalho, Maria A M
Published in Frontiers in plant science (04.12.2018)
Published in Frontiers in plant science (04.12.2018)
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Journal Article
Repeated administration of a selenium-containing indolyl compound attenuates behavioural alterations by streptozotocin through modulation of oxidative stress in mice
Bampi, Suely Ribeiro, Casaril, Angela Maria, Sabedra Sousa, Fernanda S., Pesarico, Ana Paula, Vieira, Beatriz, Lenardão, Eder João, Savegnago, Lucielli
Published in Pharmacology, biochemistry and behavior (01.08.2019)
Published in Pharmacology, biochemistry and behavior (01.08.2019)
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Journal Article
Intranasal administration of interleukin-4 ameliorates depression-like behavior and biochemical alterations in mouse submitted to the chronic unpredictable mild stress: modulation of neuroinflammation and oxidative stress
Smaniotto, Thiago Ângelo, Casaril, Angela Maria, de Andrade Lourenço, Darling, Sousa, Fernanda S., Seixas, Fabiana K., Collares, Tiago, Woloski, Rafael, da Silva Pinto, Luciano, Alves, Diego, Savegnago, Lucielli
Published in Psychopharmacology (01.04.2023)
Published in Psychopharmacology (01.04.2023)
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Journal Article
3-(4-Chlorophenylselanyl)-1-methyl-1H-indole, a new selenium compound elicits an antinociceptive and anti-inflammatory effect in mice
Birmann, Paloma T., Sousa, Fernanda S.S., de Oliveira, Daniela H., Domingues, Micaela, Vieira, Beatriz M., Lenardão, Eder J., Savegnago, Lucielli
Published in European journal of pharmacology (15.05.2018)
Published in European journal of pharmacology (15.05.2018)
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Journal Article
Komagataella pastoris KM71H modulates neuroimmune and oxidative stress parameters in animal models of depression: A proposal for a new probiotic with antidepressant-like effect
Birmann, Paloma T., Casaril, Angela M., Pesarico, Ana Paula, Caballero, Pamela S., Smaniotto, Thiago Â., Rodrigues, Rafael R., Moreira, Ângela N., Conceição, Fabricio R., Sousa, Fernanda S.S., Collares, Tiago, Seixas, Fabiana K., França, Raqueli T., Corcini, Carine D., Savegnago, Lucielli
Published in Pharmacological research (01.09.2021)
Published in Pharmacological research (01.09.2021)
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Journal Article
Neolignans isolated from Nectandra leucantha induce apoptosis in melanoma cells by disturbance in mitochondrial integrity and redox homeostasis
de Sousa, Fernanda S., Grecco, Simone S., Girola, Natalia, Azevedo, Ricardo A., Figueiredo, Carlos R., Lago, João Henrique G.
Published in Phytochemistry (Oxford) (01.08.2017)
Published in Phytochemistry (Oxford) (01.08.2017)
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Journal Article
Antinociceptive and anti-inflammatory effects of 4-(arylchalcogenyl)-1H-pyrazoles containing selenium or sulfur
Oliveira, Daniela H., Sousa, Fernanda S. S., Birmann, Paloma T., Alves, Diego, Jacob, Raquel G., Savegnago, Lucielli
Published in Pharmacological reports (01.02.2020)
Published in Pharmacological reports (01.02.2020)
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Journal Article
Lapachol acetylglycosylation enhances its cytotoxic and pro-apoptotic activities in HL60 cells
Marques, Lucas Bonfim, Ottoni, Flaviano Melo, Pinto, Mauro Cunha Xavier, Ribeiro, Juliana Martins, de Sousa, Fernanda S., Weinlich, Ricardo, de Victo, Nathalia Cruz, Kisitu, Jaffar, Holzer, Anna-Katharina, Leist, Marcel, Alves, Ricardo José, Souza-Fagundes, Elaine Maria
Published in Toxicology in vitro (01.06.2020)
Published in Toxicology in vitro (01.06.2020)
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Journal Article
3-(4-Chlorophenylselanyl)-1-methyl-1H-indole promotes recovery of neuropathic pain and depressive-like behavior induced by partial constriction of the sciatic nerve in mice
Birmann, Paloma T., Sousa, Fernanda S.S., Domingues, Micaela, Brüning, César A., Vieira, Beatriz M., Lenardão, Eder J., Savegnago, Lucielli
Published in Journal of trace elements in medicine and biology (01.07.2019)
Published in Journal of trace elements in medicine and biology (01.07.2019)
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Journal Article
Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi
Ferreira, Daiane D., Sousa, Fernanda S., Costa-Silva, Thais A., Reimão, Juliana Q., Torrecilhas, Ana C., Johns, Deidre M., Sear, Claire E., Honorio, Kathia M., Lago, João Henrique G., Anderson, Edward A., Tempone, Andre G.
Published in European journal of medicinal chemistry (15.08.2019)
Published in European journal of medicinal chemistry (15.08.2019)
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Journal Article
Immunomodulatory and Antileishmanial Activity of Phenylpropanoid Dimers Isolated from Nectandra leucantha
Costa-Silva, Thais Alves da, Grecco, Simone S, de Sousa, Fernanda S, Lago, João Henrique G, Martins, Euder G. A, Terrazas, César A, Varikuti, Sanjay, Owens, Katherine L, Beverley, Stephen M, Satoskar, Abhay R, Tempone, Andre G
Published in Journal of natural products (Washington, D.C.) (24.04.2015)
Published in Journal of natural products (Washington, D.C.) (24.04.2015)
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Structure-activity relationship study of cytotoxic neolignan derivatives using multivariate analysis and computation-aided drug design
de Sousa, Fernanda S., Baldim, João L., Azevedo, Ricardo A., Figueiredo, Carlos R., Pieper, Pauline, Sear, Claire E., Anderson, Edward A., Lago, João Henrique G.
Published in Bioorganic & medicinal chemistry letters (15.08.2020)
Published in Bioorganic & medicinal chemistry letters (15.08.2020)
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