Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
Biancur, Douglas E., Paulo, Joao A., Małachowska, Beata, Quiles Del Rey, Maria, Sousa, Cristovão M., Wang, Xiaoxu, Sohn, Albert S. W., Chu, Gerald C., Gygi, Steven P., Harper, J. Wade, Fendler, Wojciech, Mancias, Joseph D., Kimmelman, Alec C.
Published in Nature communications (03.07.2017)
Published in Nature communications (03.07.2017)
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Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
Sousa, Cristovão M., Biancur, Douglas E., Wang, Xiaoxu, Halbrook, Christopher J., Sherman, Mara H., Zhang, Li, Kremer, Daniel, Hwang, Rosa F., Witkiewicz, Agnes K., Ying, Haoqiang, Asara, John M., Evans, Ronald M., Cantley, Lewis C., Lyssiotis, Costas A., Kimmelman, Alec C.
Published in Nature (London) (25.08.2016)
Published in Nature (London) (25.08.2016)
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Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Lawson, Keith A., Sousa, Cristovão M., Zhang, Xiaoyu, Kim, Eiru, Akthar, Rummy, Caumanns, Joseph J., Yao, Yuxi, Mikolajewicz, Nicholas, Ross, Catherine, Brown, Kevin R., Zid, Abdelrahman Abou, Fan, Zi Peng, Hui, Shirley, Krall, Jordan A., Simons, Donald M., Slater, Chloe J., De Jesus, Victor, Tang, Lujia, Singh, Richa, Goldford, Joshua E., Martin, Sarah, Huang, Qian, Francis, Elizabeth A., Habsid, Andrea, Climie, Ryan, Tieu, David, Wei, Jiarun, Li, Ren, Tong, Amy Hin Yan, Aregger, Michael, Chan, Katherine S., Han, Hong, Wang, Xiaowei, Mero, Patricia, Brumell, John H., Finelli, Antonio, Ailles, Laurie, Bader, Gary, Smolen, Gromoslaw A., Kingsbury, Gillian A., Hart, Traver, Kung, Charles, Moffat, Jason
Published in Nature (London) (01.10.2020)
Published in Nature (London) (01.10.2020)
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ACLY and ACSS2 link nutrient-dependent chromatin accessibility to CD8 T cell effector responses
Kaymak, Irem, Watson, McLane J, Oswald, Brandon M, Ma, Shixin, Johnson, Benjamin K, DeCamp, Lisa M, Mabvakure, Batsirai M, Luda, Katarzyna M, Ma, Eric H, Lau, Kin, Fu, Zhen, Muhire, Brejnev, Kitchen-Goosen, Susan M, Vander Ark, Alexandra, Dahabieh, Michael S, Samborska, Bozena, Vos, Matthew, Shen, Hui, Fan, Zi Peng, Roddy, Thomas P, Kingsbury, Gillian A, Sousa, Cristovão M, Krawczyk, Connie M, Williams, Kelsey S, Sheldon, Ryan D, Kaech, Susan M, Roy, Dominic G, Jones, Russell G
Published in The Journal of experimental medicine (02.09.2024)
Published in The Journal of experimental medicine (02.09.2024)
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Journal Article
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
Nelson, Barbara S, Lin, Lin, Kremer, Daniel M, Sousa, Cristovão M, Cotta-Ramusino, Cecilia, Myers, Amy, Ramos, Johanna, Gao, Tina, Kovalenko, Ilya, Wilder-Romans, Kari, Dresser, Joseph, Davis, Mary, Lee, Ho-Joon, Nwosu, Zeribe C, Campit, Scott, Mashadova, Oksana, Nicolay, Brandon N, Tolstyka, Zachary P, Halbrook, Christopher J, Chandrasekaran, Sriram, Asara, John M, Crawford, Howard C, Cantley, Lewis C, Kimmelman, Alec C, Wahl, Daniel R, Lyssiotis, Costas A
Published in Cancer & metabolism (02.01.2020)
Published in Cancer & metabolism (02.01.2020)
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Stromal cues regulate the pancreatic cancer epigenome and metabolome
Sherman, Mara H., Yu, Ruth T., Tseng, Tiffany W., Sousa, Cristovao M., Liu, Sihao, Truitt, Morgan L., He, Nanhai, Ding, Ning, Liddle, Christopher, Atkins, Annette R., Leblanc, Mathias, Collisson, Eric A., Asara, John M., Kimmelman, Alec C., Downes, Michael, Evans, Ronald M.
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (31.01.2017)
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A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia
Lichtenstein, Daniel A., Crispin, Andrew W., Sendamarai, Anoop K., Campagna, Dean R., Schmitz-Abe, Klaus, Sousa, Cristovao M., Kafina, Martin D., Schmidt, Paul J., Niemeyer, Charlotte M., Porter, John, May, Alison, Patnaik, Mrinal M., Heeney, Matthew M., Kimmelman, Alec, Bottomley, Sylvia S., Paw, Barry H., Markianos, Kyriacos, Fleming, Mark D.
Published in Blood (13.10.2016)
Published in Blood (13.10.2016)
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Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
Sousa, Cristovão M., Biancur, Douglas E., Wang, Xiaoxu, Halbrook, Christopher J., Sherman, Mara H., Zhang, Li, Kremer, Daniel, Hwang, Rosa F., Witkiewicz, Agnes K., Ying, Haoqiang, Asara, John M., Evans, Ronald M., Cantley, Lewis C., Lyssiotis, Costas A., Kimmelman, Alec C.
Published in Nature (London) (01.12.2016)
Published in Nature (London) (01.12.2016)
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Journal Article
Unraveling the Role of Huntingtin in Breast Cancer Metastasis
Thion, Morgane S, McGuire, John R, Sousa, Cristovao M, Fuhrmann, Laetitia, Fitamant, Julien, Leboucher, Sophie, Vacher, Sophie, du Montcel, Sophie Tezenas, Bièche, Ivan, Bernet, Agnès, Mehlen, Patrick, Vincent-Salomon, Anne, Humbert, Sandrine
Published in JNCI : Journal of the National Cancer Institute (01.10.2015)
Published in JNCI : Journal of the National Cancer Institute (01.10.2015)
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Journal Article
Abstract 4986: Pancreatic cancers develop metabolic resistance pathways to glutaminase inhibition
Mancias, Joseph D., Biancur, Douglas E., Paulo, Joao A., Rey, Maria Quiles Del, Sousa, Cristovão M., Wang, Xiaoxu, Chu, Gerald C., Gygi, Steven P., Harper, J. Wade, Kimmelman, Alec C.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Unraveling the Role of Huntingtin in Breast Cancer Metastasis
Thion, Morgane S, McGuire, John R, Sousa, Cristovao M, Fuhrmann, Laetitia, Fitamant, Julien, Leboucher, Sophie, Vacher, Sophie, du Montcel, Sophie Tezenas, Bièche, Ivan, Bernet, Agnès, Mehlen, Patrick, Vincent-Salomon, Anne, Humbert, Sandrine
Published in JNCI : Journal of the National Cancer Institute (01.10.2015)
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Published in JNCI : Journal of the National Cancer Institute (01.10.2015)
Journal Article
Tissue of Origin Dictates GOT1 Dependence and Confers Synthetic Lethality to Radiotherapy
Nelson, Barbara S, Lin, Lin, Kremer, Daniel M, Sousa, Cristovao M, Cotta-Ramusino, Cecilia, Myers, Amy, Ramos, Johanna, Gao, Tina, Kovalenko, Ilya, Wilder-Romans, Kari, Dresser, Joseph, Davis, Mary, Ho-Joon, Lee, Nwosu, Zeribe C, Campit, Scott, Mashadova, Oksana, Nicolay, Brandon N, Tolstyka, Zachary P, Halbrook, Christopher J, Chandrasekaran, Sriram, Asara, John M, Crawford, Howard C, Cantley, Lewis C, Kimmelman, Alec C, Wahl, Daniel R, Lyssiotis, Costas A
Published in bioRxiv (25.07.2019)
Published in bioRxiv (25.07.2019)
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