A Perspective on Multi-target Drugs for Alzheimer’s Disease
Benek, Ondrej, Korabecny, Jan, Soukup, Ondrej
Published in Trends in pharmacological sciences (Regular ed.) (01.07.2020)
Published in Trends in pharmacological sciences (Regular ed.) (01.07.2020)
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Adamantane - A Lead Structure for Drugs in Clinical Practice
Spilovska, Katarina, Zemek, Filip, Korabecny, Jan, Nepovimova, Eugenie, Soukup, Ondrej, Windisch, Manfred, Kuca, Kamil
Published in Current medicinal chemistry (01.08.2016)
Published in Current medicinal chemistry (01.08.2016)
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Multitarget Tacrine Hybrids with Neuroprotective Properties to Confront Alzheimer's Disease
Spilovska, Katarina, Korabecny, Jan, Nepovimova, Eugenie, Dolezal, Rafael, Mezeiova, Eva, Soukup, Ondrej, Kuca, Kamil
Published in Current topics in medicinal chemistry (01.04.2017)
Published in Current topics in medicinal chemistry (01.04.2017)
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The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs
Tsianou, Chrysostomi Christina, Kvetina, Jaroslav, Radochova, Vera, Kohoutova, Darina, Rejchrt, Stanislav, Valis, Martin, Zdarova Karasova, Jana, Tacheci, Ilja, Knoblochova, Veronika, Soukup, Ondrej, Bures, Jan
Published in PloS one (01.06.2023)
Published in PloS one (01.06.2023)
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A systematic review on donepezil-based derivatives as potential cholinesterase inhibitors for Alzheimer's disease
Korabecny, Jan, Spilovska, Katarina, Mezeiova, Eva, Benek, Ondrej, Juza, Radomir, Kaping, Daniel, Soukup, Ondrej
Published in Current medicinal chemistry (01.01.2019)
Published in Current medicinal chemistry (01.01.2019)
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SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides
Gorecki, Lukas, Korabecny, Jan, Musilek, Kamil, Malinak, David, Nepovimova, Eugenie, Dolezal, Rafael, Jun, Daniel, Soukup, Ondrej, Kuca, Kamil
Published in Archives of toxicology (01.12.2016)
Published in Archives of toxicology (01.12.2016)
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Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
Chalupova, Katarina, Korabecny, Jan, Bartolini, Manuela, Monti, Barbara, Lamba, Doriano, Caliandro, Rosanna, Pesaresi, Alessandro, Brazzolotto, Xavier, Gastellier, Anne-Julie, Nachon, Florian, Pejchal, Jaroslav, Jarosova, Michaela, Hepnarova, Vendula, Jun, Daniel, Hrabinova, Martina, Dolezal, Rafael, Zdarova Karasova, Jana, Mzik, Martin, Kristofikova, Zdena, Misik, Jan, Muckova, Lubica, Jost, Petr, Soukup, Ondrej, Benkova, Marketa, Setnicka, Vladimir, Habartova, Lucie, Chvojkova, Marketa, Kleteckova, Lenka, Vales, Karel, Mezeiova, Eva, Uliassi, Elisa, Valis, Martin, Nepovimova, Eugenie, Bolognesi, Maria Laura, Kuca, Kamil
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
AlFadly, Ehab D., Elzahhar, Perihan A., Tramarin, Anna, Elkazaz, Salwa, Shaltout, Hossam, Abu-Serie, Marwa M., Janockova, Jana, Soukup, Ondrej, Ghareeb, Doaa A., El-Yazbi, Ahmed F., Rafeh, Rim W., Bakkar, Nour-Mounira Z., Kobeissy, Firas, Iriepa, Isabel, Moraleda, Ignacio, Saudi, Manal N.S., Bartolini, Manuela, Belal, Ahmed S.F.
Published in European journal of medicinal chemistry (01.04.2019)
Published in European journal of medicinal chemistry (01.04.2019)
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Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases
Bautista‐Aguilera, Óscar M., Hagenow, Stefanie, Palomino‐Antolin, Alejandra, Farré‐Alins, Víctor, Ismaili, Lhassane, Joffrin, Pierre‐Louis, Jimeno, María L., Soukup, Ondřej, Janočková, Jana, Kalinowsky, Lena, Proschak, Ewgenij, Iriepa, Isabel, Moraleda, Ignacio, Schwed, Johannes S., Romero Martínez, Alejandro, López‐Muñoz, Francisco, Chioua, Mourad, Egea, Javier, Ramsay, Rona R., Marco‐Contelles, José, Stark, Holger
Published in Angewandte Chemie International Edition (02.10.2017)
Published in Angewandte Chemie International Edition (02.10.2017)
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Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules
Hamulakova, Slavka, Poprac, Patrik, Jomova, Klaudia, Brezova, Vlasta, Lauro, Peter, Drostinova, Lenka, Jun, Daniel, Sepsova, Vendula, Hrabinova, Martina, Soukup, Ondrej, Kristian, Pavol, Gazova, Zuzana, Bednarikova, Zuzana, Kuca, Kamil, Valko, Marian
Published in Journal of inorganic biochemistry (01.08.2016)
Published in Journal of inorganic biochemistry (01.08.2016)
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Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies
Mamun, Abdullah Al, Pidaný, Filip, Hulcová, Daniela, Maříková, Jana, Kučera, Tomáš, Schmidt, Monika, Catapano, Maria Carmen, Hrabinová, Martina, Jun, Daniel, Múčková, Lubica, Kuneš, Jiří, Janoušek, Jiří, Andrýs, Rudolf, Nováková, Lucie, Peřinová, Rozálie, Maafi, Negar, Soukup, Ondřej, Korábečný, Jan, Cahlíková, Lucie
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Orexin supplementation in narcolepsy treatment: A review
Nepovimova, Eugenie, Janockova, Jana, Misik, Jan, Kubik, Stepan, Stuchlik, Ales, Vales, Karel, Korabecny, Jan, Mezeiova, Eva, Dolezal, Rafael, Soukup, Ondrej, Kobrlova, Tereza, Pham, Ngoc Lam, Nguyen, Thuy Duong, Konecny, Jan, Kuca, Kamil
Published in Medicinal research reviews (01.05.2019)
Published in Medicinal research reviews (01.05.2019)
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Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease
Vrabec, Rudolf, Maříková, Jana, Ločárek, Miroslav, Korábečný, Jan, Hulcová, Daniela, Hošťálková, Anna, Kuneš, Jiří, Chlebek, Jakub, Kučera, Tomáš, Hrabinová, Martina, Jun, Daniel, Soukup, Ondřej, Andrisano, Vincenza, Jenčo, Jaroslav, Šafratová, Marcela, Nováková, Lucie, Opletal, Lubomír, Cahlíková, Lucie
Published in Phytochemistry (Oxford) (01.02.2022)
Published in Phytochemistry (Oxford) (01.02.2022)
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Is It the Twilight of BACE1 Inhibitors?
Hrabinova, Martina, Pejchal, Jaroslav, Kucera, Tomas, Jun, Daniel, Schmidt, Monika, Soukup, Ondrej
Published in Current neuropharmacology (2021)
Published in Current neuropharmacology (2021)
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Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists
Chvojkova, Marketa, Kolar, David, Kovacova, Katarina, Cejkova, Lada, Misiachna, Anna, Hakenova, Kristina, Gorecki, Lukas, Horak, Martin, Korabecny, Jan, Soukup, Ondrej, Vales, Karel
Published in Biomedicine & pharmacotherapy (01.07.2024)
Published in Biomedicine & pharmacotherapy (01.07.2024)
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Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease
Mezeiova, Eva, Prchal, Lukas, Hrabinova, Martina, Muckova, Lubica, Pulkrabkova, Lenka, Soukup, Ondrej, Misiachna, Anna, Janousek, Jiri, Fibigar, Jakub, Kucera, Tomas, Horak, Martin, Makhaeva, Galina F., Korabecny, Jan
Published in Biomedicine & pharmacotherapy (01.04.2024)
Published in Biomedicine & pharmacotherapy (01.04.2024)
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