Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study
Loomes, Kathleen M., Squires, Robert H., Kelly, Deirdre, Rajwal, Sanjay, Soufi, Nisreen, Lachaux, Alain, Jankowska, Irena, Mack, Cara, Setchell, Kenneth D. R., Karthikeyan, Palaniswamy, Kennedy, Ciara, Dorenbaum, Alejandro, Desai, Nirav K., Garner, Will, Jaecklin, Thomas, Vig, Pamela, Miethke, Alexander, Thompson, Richard J.
Published in Hepatology communications (01.09.2022)
Published in Hepatology communications (01.09.2022)
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Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice
Schweitzer, George G., Chen, Zhouji, Gan, Connie, McCommis, Kyle S., Soufi, Nisreen, Chrast, Roman, Mitra, Mayurranjan S., Yang, Kui, Gross, Richard W., Finck, Brian N.
Published in Journal of lipid research (01.04.2015)
Published in Journal of lipid research (01.04.2015)
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Elevated transaminases in congenital central hypoventilation syndrome
Wang, Rachel Y, Wang, Victoria S, Keens, Thomas G, Chai, Yan, Soufi, Nisreen, Perez, Iris A
Published in ERJ open research (01.01.2024)
Published in ERJ open research (01.01.2024)
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Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis
Thompson, Richard J., Artan, Reha, Baumann, Ulrich, Calvo, Pier Luigi, Czubkowski, Piotr, Dalgic, Buket, D’Antiga, Lorenzo, Di Giorgio, Angelo, Durmaz, Özlem, Gonzalès, Emmanuel, Grammatikopoulos, Tassos, Gupte, Girish, Hardikar, Winita, Houwen, Roderick H.J., Kamath, Binita M., Karpen, Saul J., Lacaille, Florence, Lachaux, Alain, Lainka, Elke, Loomes, Kathleen M., Mack, Cara L., Mattsson, Jan P., McKiernan, Patrick, Ni, Quanhong, Özen, Hasan, Rajwal, Sanjay R., Roquelaure, Bertrand, Shteyer, Eyal, Sokal, Etienne, Sokol, Ronald J., Soufi, Nisreen, Sturm, Ekkehard, Tessier, Mary Elizabeth, van der Woerd, Wendy L., Verkade, Henkjan J., Vittorio, Jennifer M., Wallefors, Terese, Warholic, Natalie, Yu, Qifeng, Horn, Patrick, Kjems, Lise
Published in JHEP reports (01.08.2023)
Published in JHEP reports (01.08.2023)
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Post-Transplant Disease Recurrence in Pediatric PSC
Soufi, Nisreen, Bazerbachi, Fateh, Deneau, Mark
Published in Current gastroenterology reports (01.09.2018)
Published in Current gastroenterology reports (01.09.2018)
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Journal Article
Serum bile acid control in long-term maralixibat-treated patients is associated with native liver survival in children with progressive familial intrahepatic cholestasis due to bile salt export pump deficiency
Thompson, Richard, Kelly, Deirdre, Miethke, Alexander, Rajwal, Sanjay, Soufi, Nisreen, Jankowska, Irena, Mack, Cara, Lachaux, Alain, Jaecklin, Thomas, Vig, Pamela, Wardle, Andrew, Squires, Robert, Loomes, Kathleen
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
LBO08 - Serum bile acid control in long-term maralixibat-treated patients is associated with native liver survival in children with progressive familial intrahepatic cholestasis due to bile salt export pump deficiency
Thompson, Richard, Kelly, Deirdre, Miethke, Alexander, Rajwal, Sanjay, Soufi, Nisreen, Jankowska, Irena, Mack, Cara, Lachaux, Alain, Jaecklin, Thomas, Vig, Pamela, Wardle, Andrew, Squires, Robert, Loomes, Kathleen
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) Index: A Prognostic Tool for Children
Deneau, Mark R., Mack, Cara, Perito, Emily R., Ricciuto, Amanda, Valentino, Pamela L., Amin, Mansi, Amir, Achiya Z., Aumar, Madeleine, Auth, Marcus, Broderick, Annemarie, DiGuglielmo, Matthew, Draijer, Laura G., Tavares Fagundes, Eleonora Druve, El‐Matary, Wael, Ferrari, Federica, Furuya, Katryn N., Gupta, Nitika, Hochberg, Jessica T., Homan, Matjaz, Horslen, Simon, Iorio, Raffaele, Jensen, M. Kyle, Jonas, Maureen M., Kamath, Binita M., Kerkar, Nanda, Kim, Kyung Mo, Kolho, Kaija‐Leena, Koot, Bart G.P., Laborda, Trevor J., Lee, Christine K., Loomes, Kathleen M., Martinez, Mercedes, Miethke, Alexander, Miloh, Tamir, Mogul, Douglas, Mohammad, Saeed, Mohan, Parvathi, Moroz, Stacy, Ovchinsky, Nadia, Palle, Sirish, Papadopoulou, Alexandra, Rao, Girish, Rodrigues Ferreira, Alexandre, Sathya, Pushpa, Schwarz, Kathleen B., Shah, Uzma, Shteyer, Eyal, Singh, Ruchi, Smolka, Vratislav, Soufi, Nisreen, Tanaka, Atsushi, Varier, Raghu, Vitola, Bernadette, Woynarowski, Marek, Zerofsky, Melissa, Zizzo, Andréanne, Guthery, Stephen L.
Published in Hepatology (Baltimore, Md.) (01.03.2021)
Published in Hepatology (Baltimore, Md.) (01.03.2021)
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Oral vancomycin is associated with improved inflammatory bowel disease clinical outcomes in primary sclerosing cholangitis‐associated inflammatory bowel disease (PSC‐IBD): A matched analysis from the Paediatric PSC Consortium
Ricciuto, Amanda, Liu, Kuan, El‐Matary, Wael, Amin, Mansi, Amir, Achiya Z., Aumar, Madeleine, Auth, Marcus, Di Guglielmo, Matthew D., Druve Tavares Fagundes, Eleonora, Rodrigues Ferreira, Alexandre, Furuya, Katryn N., Gupta, Nitika, Guthery, Stephen, Horslen, Simon P., Jensen, Kyle, Kamath, Binita M., Kerkar, Nanda, Koot, B. G. P., Laborda, Trevor J., Lee, Christine K., Loomes, Kathleen M., Mack, Cara, Martinez, Mercedes, Montano‐Loza, Aldo, Ovchinsky, Nadia, Papadopoulou, Alexandra, Perito, Emily R., Sathya, Pushpa, Schwarz, Kathleen B., Shah, Uzma, Shteyer, Eyal, Soufi, Nisreen, Stevens, James Patrick, Taylor, Amy, Tessier, M. Elizabeth, Valentino, Pamela, Woynarowski, Marek, Deneau, Mark
Published in Alimentary pharmacology & therapeutics (01.05.2024)
Published in Alimentary pharmacology & therapeutics (01.05.2024)
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Risk of variceal hemorrhage and pretransplant mortality in children with biliary atresia
Bass, Lee M., Ye, Wen, Leung, Daniel H., Murray, Karen F., Molleston, Jean P., Romero, Rene, Rosenthal, Philip, Loomes, Kathleen M., Wang, Kasper S., Squires, Robert H., Miethke, Alexander, Ng, Vicky L., Kyle Jensen, M., Sokol, Ronald J., Magee, John C., Alonso, Estella, Bass, Lee, Kelly, Susan, Melin‐Aldana, Hector, Bove, Kevin, Heubi, James, Miethke, Alexander, Tiao, Greg, Chapman, Erin, Sokol, Ronald, Feldman, Amy, Mack, Cara, Narkewicz, Michael, Sundaram, Shikha, Van Hove, Johan, Garcia, Benigno, Kauma, Mikaela, Kocher, Kendra, Steinbeiss, Matthew, Lovell, Mark, Loomes, Kathleen, Rand, Elizabeth, Russo, Pierre, Spinner, Nancy, Erlichman, Jessi, Pakstis, Dina, King, Sakya, Squires, Robert, Sindhi, Rakesh, Venkat, Veena, McKiernan, Patrick, Haberstroh, Lori, Curry, Joanna, Langlois, Camille, Kim, Grace, Teckman, Jeffery, Kociela, Vikki, Nagy, Rosemary, Patel, Shraddha, Cerkoski, Jacqueline, Bozic, Molly, Subbarao, Girish, Klipsch, Ann, Cummings, Oscar, Hsu, Evelyn, Cooper, Kara, Young, Melissa, Finn, Laura, Kamath, Binita, Ng, Vicky, Quammie, Claudia, Putra, Juan, Sharma, Deepika, Guthery, Stephen, Rutherford, Ann, Lowichik, Amy, Book, Linda, Meyers, Rebecka, Hall, Tyler, Wang, Kasper, Thomas, Danny, Goodhue, Catherine, Wang, Larry, Soufi, Nisreen, Thomas, Daniel, Karpen, Saul, Romero, Rene, Tory, Rita, Abramowsky, Carlos, McFall, Jeanette, Shneider, Benjamin, Harpavat, Sanjiv, Leung, Daniel, Tessier, Mary, Schady, Deborah, Olvera, Diego, Banks, Christina, Thompson, Richard, Doo, Edward, Hoofnagle, Jay, Sherker, Averell, Hall, Sherry, Merion, Robert, Spino, Cathie, Ye, Wen
Published in Hepatology (Baltimore, Md.) (01.09.2022)
Published in Hepatology (Baltimore, Md.) (01.09.2022)
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Journal Article
Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease
Leung, Daniel H, Devaraj, Sridevi, Goodrich, Nathan P, Chen, Xinpu, Rajapakshe, Deepthi, Ye, Wen, Andreev, Victor, Minard, Charles G, Guffey, Danielle, Molleston, Jean P, Bass, Lee M, Karpen, Saul J, Kamath, Binita M, Wang, Kasper S, Sundaram, Shikha S, Rosenthal, Philip, McKiernan, Patrick, Loomes, Kathleen M, Jensen, M Kyle, Horslen, Simon P, Bezerra, Jorge A, Magee, John C, Merion, Robert M, Sokol, Ronald J, Shneider, Benjamin L, Alonso, Estella, Bass, Lee, Kelly, Susan, Riordan, Mary, Melin-Aldana, Hector, Bezerra, Jorge, Bove, Kevin, Heubi, James, Miethke, Alexander, Tiao, Greg, Denlinger, Julie, Chapman, Erin, Sokol, Ronald, Feldman, Amy, Mack, Cara, Narkewicz, Michael, Suchy, Frederick, Sundaram, Shikha S, Van Hove, Johan, Garcia, Benigno, Kauma, Mikaela, Kocher, Kendra, Steinbeiss, Matthew, Lovell, Mark, Loomes, Kathleen M, Piccoli, David, Rand, Elizabeth, Russo, Pierre, Spinner, Nancy, Erlichman, Jessi, Stalford, Samantha, Pakstis, Dina, King, Sakya, Squires, Robert, Sindhi, Rakesh, Venkat, Veena, Bukauskas, Kathy, McKiernan, Patrick, Haberstroh, Lori, Squires, James, Rosenthal, Philip, Bull, Laura, Curry, Joanna, Langlois, Camille, Kim, Grace, Teckman, Jeffery, Kociela, Vikki, Nagy, Rosemary, Patel, Shraddha, Cerkoski, Jacqueline, Molleston, Jean P, Bozic, Molly, Subbarao, Girish, Klipsch, Ann, Sawyers, Cindy, Cummings, Oscar, Horslen, Simon P, Murray, Karen, Hsu, Evelyn, Cooper, Kara, Young, Melissa, Finn, Laura, Kamath, Binita M, Ng, Vicky, Quammie, Claudia, Putra, Juan, Sharma, Deepika, Parmar, Aishwarya, Guthery, Stephen, Jensen, Kyle, Rutherford, Ann, Lowichik, Amy, Book, Linda, Meyers, Rebecka, Hall, Tyler
Published in Hepatology (Baltimore, Md.) (01.02.2023)
Published in Hepatology (Baltimore, Md.) (01.02.2023)
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Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
HALL, Angela M, SOUFI, Nisreen, CHAMBERS, Kari T, ZHOUJI CHEN, SCHWEITZER, George G, MCCOMMIS, Kyle S, ERION, Derek M, GRAHAM, Mark J, XIONG SU, FINCK, Brian N
Published in Diabetes (New York, N.Y.) (01.07.2014)
Published in Diabetes (New York, N.Y.) (01.07.2014)
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LBO-08-Growth analysis in children with progressive familial intrahepatic cholestasis treated with the apical sodium-dependent bile acid transporter inhibitor maralixibat
Thompson, Richard, Kelly, Deirdre, Rajwal, Sanjay, Miethke, Alexander, Soufi, Nisreen, Rivet, Christine, Jankowska, Irena, mack, Cara, Jaecklin, Thomas, Squires, Robert, Loomes, Kathleen
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
Severe Late-Onset Acute Cellular Rejection in a Pediatric Patient With Isolated Small Intestinal Transplant Rescued With Aggressive Immunosuppressive Approach: A Case Report
Narang, Amrita, Xi, Dong, Mitsinikos, Tania, Genyk, Yuri, Thomas, Dan, Kohli, Rohit, Lin, Chuan-Hao, Soufi, Nisreen, Warren, Mikako, Merritt, Russell, Yanni, George
Published in Transplantation proceedings (01.11.2019)
Published in Transplantation proceedings (01.11.2019)
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Journal Article
Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study
Ng, Vicky L., Sorensen, Lisa G., Alonso, Estella M., Fredericks, Emily M., Ye, Wen, Moore, Jeff, Karpen, Saul J., Shneider, Benjamin L., Molleston, Jean P., Bezerra, Jorge A., Murray, Karen F., Loomes, Kathleen M., Rosenthal, Philip, Squires, Robert H., Wang, Kasper, Arnon, Ronen, Schwarz, Kathleen B., Turmelle, Yumirle P., Haber, Barbara H., Sherker, Averell H., Magee, John C., Sokol, Ronald J., Hertel, Paula M., Harpavat, Sanjiv, Brandt, Mary L., Leung, Daniel H., Karnsakul, Wikrom, Torrance, Rebecca, Hall, Sherry, Doo, Edward, Hoofnagle, Jay H., Whitington, Peter, Bass, Lee, Miethke, Alexander G., Heubi, James E., Setchell, Kenneth, Bove, Kevin E., Tiao, Greg, Mack, Cara L., Narkewicz, Michael R., Feldman, Amy G., Sundaram, Shikha S., Suchy, Frederick J., Karrer, Frederick M., Lovell, Mark, Van Hove, Johan L., Rand, Elizabeth B., Squires, James E., Venkat, Veena L., Sindhi, Rakesh, Ranganathan, Sarangarajan, Bull, Laura, Teckman, Jeffrey, Bozic, Molly, Subbarao, Girish, Horslen, Simon, Hsu, Evelyn, Finn, Laura, Healey, Patrick, Kohli, Rohit, Thomas, Danny, Soufi, Nisreen, Michail, Sonia, Clifton, Matt, Gupta, Nitika, Romero, Rene, Vos, Miriam, Caltharp, Shelley, Kamath, Binita M., Ling, Simon C., Gold, Anna, Fecteau, Annie, Guthery, Stephen L., Jensen, Kyle, Meyers, Rebecka, Lowichik, Amy, Book, Linda, Merion, Robert M., Spino, Cathie, Jones, Karen
Published in The Journal of pediatrics (01.05.2018)
Published in The Journal of pediatrics (01.05.2018)
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Journal Article
Colorectal Dysplasia and Cancer in Pediatric-Onset Ulcerative Colitis Associated With Primary Sclerosing Cholangitis
El-Matary, Wael, Guthery, Stephen L., Amir, Achiya Z., DiGuglielmo, Matthew, Draijer, Laura G., Furuya, Katryn N., Gupta, Nitika, Hochberg, Jessica T., Horslen, Simon, Kerkar, Nanda, Koot, Bart G.P., Laborda, Trevor J., Loomes, Kathleen M., Mack, Cara, Martinez, Mercedes, Miethke, Alexander, Miloh, Tamir, Mogul, Douglas, Mohammed, Saeed, Moroz, Stacy, Ovchinsky, Nadia, Perito, Emily R., Rao, Girish, Ricciuto, Amanda, Sathya, Pushpa, Schwarz, Kathleen B., Shah, Uzma, Singh, Ruchi, Soufi, Nisreen, Valentino, Pamela L., Zizzo, Andréanne, Deneau, Mark R.
Published in Clinical gastroenterology and hepatology (01.05.2021)
Published in Clinical gastroenterology and hepatology (01.05.2021)
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Journal Article
Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension
Teckman, Jeffrey, Rosenthal, Philip, Hawthorne, Kieran, Spino, Cathie, Bass, Lee M., Kerkar, Nanda, Magee, John C., Karpen, Saul, Heubi, James E., Molleston, Jean P., Kamath, Binita M., Guthery, Stephen L., Sherker, Averell H., Alonso, Estella, Bass, Lee, Kelly, Susan, Melin-Aldana, Hector, Bove, Kevin, Heubi, James, Miethke, Alexander, Tiao, Greg, Denlinger, Julie, Chapman, Erin, Feldman, Amy, Narkewicz, Michael, Suchy, Frederick, Sundaram, Shikha, Van Hove, Johan, Garcia, Benigno, Kauma, Mikaela, Kocher, Kendra, Steinbeiss, Matthew, Lovell, Mark, Rand, Elizabeth, Russo, Pierre, Erlichman, Jessi, Pakstis, Dina, King, Sakya, Squires, Robert, Sindhi, Rakesh, Venkat, Veena, McKiernan, Patrick, Haberstroh, Lori, Squires, James, Curry, Joanna, Langlois, Camille, Kim, Grace, Teckman, Jeffery, Kociela, Vikki, Nagy, Rosemary, Patel, Shraddha, Cerkoski, Jacqueline, Molleston, Jean P., Bozic, Molly, Subbarao, Girish, Klipsch, Ann, Sawyers, Cindy, Cummings, Oscar, Horslen, Simon, Murray, Karen, Hsu, Evelyn, Cooper, Kara, Young, Melissa, Finn, Laura, Ng, Vicky, Quammie, Claudia, Putra, Juan, Sharma, Deepika, Guthery, Stephen, Rutherford, Ann, Lowichik, Amy, Book, Linda, Meyers, Rebecka, Hall, Tyler, Wang, Kasper, Thomas, Danny, Goodhue, Catherine, Kohli, Rohit, Soufi, Nisreen, Thomas, Daniel, Karpen, Saul, Gupta, Nitika, Tory, Rita, Berauer, John-Paul, Abramowsky, Carlos, McFall, Jeanette, Shneider, Benjamin, Harpavat, Sanjiv, Hertel, Paula, Leung, Daniel, Schady, Deborah, Banks, Christina, Doo, Edward, Hoofnagle, Jay, Sherker, Averell, Hall, Sherry, Magee, John, Merion, Robert, Spino, Cathie, Ye, Wen
Published in The Journal of pediatrics (01.12.2020)
Published in The Journal of pediatrics (01.12.2020)
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Journal Article
Inhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities but Not Inflammation and Injury in Mice
Soufi, Nisreen, Hall, Angela M., Chen, Zhouji, Yoshino, Jun, Collier, Sara L., Mathews, James C., Brunt, Elizabeth M., Albert, Carolyn J., Graham, Mark J., Ford, David A., Finck, Brian N.
Published in The Journal of biological chemistry (24.10.2014)
Published in The Journal of biological chemistry (24.10.2014)
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Journal Article
L3 Effects on serum bile acids, pruritus, and safety with up to 72 weeks of odevixibat treatment: pooled data from the PEDFIC 1 and PEDFIC 2 studies in children with progressive familial intrahepatic cholestasis
Loomes, Kathleen M, Verkade, Henkjan J, Thompson, Richard J, Kamath, Binita M, Hardikar, Winita, Lacaille, Florence, Mozer-Glassberg, Yael, Shteyer, Eyal, Calvo, Pier Luigi, Dalgic, Buket, Grammatikopoulos, Tassos, Rajwal, Sanjay R, Vittorio, Jennifer M, Soufi, Nisreen, McKiernan, Patrick, Tessier, Mary Elizabeth, Yu, Qifeng, Kjems, Lise, Horn, Patrick
Published in Frontline gastroenterology (01.04.2022)
Published in Frontline gastroenterology (01.04.2022)
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