Pancreatic cancer heterogeneity and response to Mek inhibition
Pedersen, K, Bilal, F, Bernadó Morales, C, Salcedo, M T, Macarulla, T, Massó-Vallés, D, Mohan, V, Vivancos, A, Carreras, M-J, Serres, X, Abu-Suboh, M, Balsells, J, Allende, E, Sagi, I, Soucek, L, Tabernero, J, Arribas, J
Published in Oncogene (05.10.2017)
Published in Oncogene (05.10.2017)
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A spotlight on cancer researchers in Spain: new paradigms and disruptive ideas
Ramón y Cajal, S., Sancho, P., Soucek, L., Peinado, H., Abad, M., Valiente, M., Efeyan, A., Pardo, J., Quesada, V., Jimeno, J., Duque, P. M., Antón, A., Varela, I., Schuhmacher, A. J.
Published in Clinical & translational oncology (01.06.2020)
Published in Clinical & translational oncology (01.06.2020)
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749 Myc – a Non Redundant Function in Cancer
Soucek, L, Whitfield, J.R, Sodir, N.M, Masso-Valles, D, Swigart, L. Brown, Evan, G.I
Published in European journal of cancer (1990) (01.07.2012)
Published in European journal of cancer (1990) (01.07.2012)
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751 MYC Inhibition as a Therapeutic Strategy in Glioma
Annibali, D, Whitfield, J.R, Favuzzi, E, Nasi, S, Swigart, L. Brown, Evan, G.I, Soucek, L
Published in European journal of cancer (1990) (01.07.2012)
Published in European journal of cancer (1990) (01.07.2012)
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Journal Article
773: A novel pharmacological approach to inhibit Myc in cancer
Beaulieu, M.E, Whitfield, J.R, Jauset, T, Massó-Vallés, D, Serrano, E, Canals, F, Lavigne, P, Montagne, M, Maltais, L, Soucek, L
Published in European journal of cancer (1990) (01.07.2014)
Published in European journal of cancer (1990) (01.07.2014)
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Journal Article
916 Modeling Pharmacological Inhibition of Bruton's Tyrosine Kinase (BTK) as a Therapy for Insulinoma and Pancreatic Ductal Adenocarcinoma
Soucek, L, Masso-Valles, D, Jauset, T, Whitfield, J.R, Buggy, J.J, Sodir, N.M, Kortlever, R, Swigart, L. Brown, Evan, G.I
Published in European journal of cancer (1990) (01.07.2012)
Published in European journal of cancer (1990) (01.07.2012)
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Journal Article
Enantiopure molecules form apparently racemic monolayers of chiral cyclic pentamers
Heiner, Benjamin R, Handy, Kaitlyn M, Devlin, Angela M, Soucek, Jewel L, Pittsford, Alexander M, Turner, David A, Petersen, Jacob P, Oliver, Allen G, Corcelli, Steven A, Kandel, S Alex
Published in Physical chemistry chemical physics : PCCP (09.10.2024)
Published in Physical chemistry chemical physics : PCCP (09.10.2024)
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Dose escalation study of OMO-103, a first in class Pan-MYC-Inhibitor in patients (pts) with advanced solid tumors
Garralda, E., Moreno, V., Alonso, G., Corral, E., Hernandez-Guerrero, T., Ramon, J., Doger de Spéville, B., Martinez, E., Soucek, L., Niewel, M., Calvo, E.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice
Soucek, Laura, Whitfield, Jonathan R, Sodir, Nicole M, Massó-Vallés, Daniel, Serrano, Erika, Karnezis, Anthony N, Swigart, Lamorna Brown, Evan, Gerard I
Published in Genes & development (01.03.2013)
Published in Genes & development (01.03.2013)
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132 (PB120): Pharmacokinetic and pharmacodynamic analyses of OMO-103 in preclinical and patient tissues
Martín, S. Martínez, Casacuberta-Serra, S., López-Estévez, S., Foradada, L., Cano, V. Castillo, Kaur, J., Thabussot, H., Morales, J., Niewel, M., Nonell, L., Arqués, O., Beaulieu, M.E., Soucek, L.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Journal Article
217 (PB205): Therapeutic impact and reactivation of tumor immunity by MYC inhibition in KRAS-driven NSCLC with diverse mutational landscapes
González-Larreategui, I., Vera, L., Capitán-Leo, D., Sansegundo, L., Giuntini, F., Martínez-Martín, S., Thabussot, H., López-Estévez, S., del Pozo, E. Serrano, Grueso, J., Foradada, L., Macaya, I., Beaulieu, M.E., Vicent, S., Casacuberta-Serra, S., Soucek, L.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Journal Article
MYC inhibition by Omomyc unveils a prognostic gene signature in Melanoma
Zacarias-Fluck, M., Massó-Vallés, D., Kaur, J., Giuntini, F., Casacuberta-Serra, S., Jauset, T., Martin-Fernández, G., Beaulieu, M.E., Whitfield, J.R., Soucek, L.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
213 (PB201): MYC Inhibition by OMO-103 Reprograms Tumor Immunity and Enhances Immunotherapy Efficacy in KRAS Mutant NSCLC
Serra, S. Casacuberta, González-Larreategui, I., Vera, L., Adradas, V., Martínez-Martín, S., Peressini, M., López-Estévez, S., Arnal, M., Sansegundo, L., del Pozo, E. Serrano, Grueso, J., Foradada, L., Thabussot, H., Giuntini, F., Whitfield, J., Beaulieu, M.E., Zugazagoitia, J., Vicent, S., Soucek, L.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Journal Article
Omomyc downregulates MYC transcriptional signature in preclinical models of solid tumours and shows long half-life in tumour tissue
Martínez Martín, S., López-Estévez, S., Foradada, L., Kaur, J., Serrano, E., González-Larreategui, Í., Giuntini, F., Casacuberta-Serra, S., Thabussot, H., Castillo Cano, V., Nonell, L., Soucek, L., Beaulieu, M.E.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
Characterization of KRAS-driven NSCLC cell lines with diverse mutational landscape and assessment of their response to MYC inhibition
González-Larreategui, Í., Vera, L., Giuntini, F., Martínez-Martín, S., Grueso, J., López, S., Serrano del Pozo, E., Thabussot, H., Macaya, I., Beaulieu, M.E., Vicent, S., Casacuberta-Serra, S., Soucek, L.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
Omomyc mini-protein can be directly and continuously delivered to the brain to prevent glioblastoma in patient-derived xenograft mouse models
Whitfield, J., Foradada, L., Serrano, E., Thabussot, H., López-Estévez, S., Martín-Fernández, G., Grueso, J., Bove, J., Juanola, J., Castillo Cano, V., Squatrito, M., Jimenez Schumacher, A., Zacarías-Fluck, M., Beaulieu, M.E., Soucek, L.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
MYC inhibition by Omomyc as a therapeutic strategy for (KRAS-mutated) colorectal cancer
Kaur, J., Martínez-Martín, S., Foradada, L., López-Estévez, S., Serrano, E., Mártin-Fernández, G., Thabussot, H., Castillo Cano, V., Casacuberta-Serra, S., Zacarías-Fluck, M.F., Grueso, J., Beaulieu, M.E., Whitfield, J.R., Soucek, L.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
Omomyc as a novel therapeutic strategy against metastatic triplenegative breast cancer, alone and in combination with the standard of care
Giuntini, F., Massó-Vallés, D., González-Larreategui, Í., Thabussot, H., Kaur, J., Zacarías-Fluck, M., Casacuberta-Serra, S., Martínez-Martín, S., Foradada-Felip, L., Serrano, E., Martín-Fernández, G., Castillo Cano, V., López-Estévez, S., Serra, V., Whitfield, J., Beaulieu, M.E., Soucek, L.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Journal Article
MYC inhibition by OMO-103 induces immune cell recruitment in preclinical models of NSCLC and modulates the cytokine and chemokine profiles of Phase I patients showing stable disease
Casacuberta Serra, S., Martínez-Martín, S., González-Larreategui, Í., López-Estévez, S., Jauset, T., Zacarías-Fluck, M., Massó-Vallés, D., Martín, G., Foradada, L., Grueso, J., Serrano, E., Thabussot, H., Castillo Cano, V., Whitfield, J.R., Morales, J., Niewel, M., Beaulieu, M.E., Soucek, L.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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