Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function
Jiang, Tingting, Sánchez‐Rivera, Francisco J., Soto‐Feliciano, Yadira M., Yang, Qiyuan, Song, Chun‐Qing, Bhuatkar, Arjun, Haynes, Cole M, Hemann, Michael T., Xue, Wen
Published in Hepatology (Baltimore, Md.) (01.07.2021)
Published in Hepatology (Baltimore, Md.) (01.07.2021)
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Journal Article
Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy
Pallasch, Christian P., Leskov, Ilya, Braun, Christian J., Vorholt, Daniela, Drake, Adam, Soto-Feliciano, Yadira M., Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina, Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu, Hemann, Michael T.
Published in Cell (30.01.2014)
Published in Cell (30.01.2014)
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Journal Article
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Schneider, William M., Luna, Joseph M., Soto-Feliciano, Yadira M., Ashbrook, Alison W., Le Pen, Jérémie, Leal, Andrew A., Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F., Peace, Avery, Zuber, Johannes, Allis, C. David, Lowe, Scott W., MacDonald, Margaret R., Poirier, John T., Rice, Charles M.
Published in Cell Host & Microbe (10.02.2021)
Published in Cell Host & Microbe (10.02.2021)
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Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma
Chen, Xiao, Li, Yinglu, Zhu, Fang, Xu, Xinjing, Estrella, Brian, Pazos, 2nd, Manuel A, McGuire, John T, Karagiannis, Dimitris, Sahu, Varun, Mustafokulov, Mustafo, Scuoppo, Claudio, Sánchez-Rivera, Francisco J, Soto-Feliciano, Yadira M, Pasqualucci, Laura, Ciccia, Alberto, Amengual, Jennifer E, Lu, Chao
Published in Nature communications (17.07.2023)
Published in Nature communications (17.07.2023)
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Journal Article
Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors
Karagiannis, Dimitris, Wu, Warren, Li, Albert, Hayashi, Makiko, Chen, Xiao, Yip, Michaela, Mangipudy, Vaibhav, Xu, Xinjing, Sánchez-Rivera, Francisco J., Soto-Feliciano, Yadira M., Ye, Jiangbin, Papagiannakopoulos, Thales, Lu, Chao
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
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Journal Article
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes
Soto-Feliciano, Yadira M, Bartlebaugh, Jordan M E, Liu, Yunpeng, Sánchez-Rivera, Francisco J, Bhutkar, Arjun, Weintraub, Abraham S, Buenrostro, Jason D, Cheng, Christine S, Regev, Aviv, Jacks, Tyler E, Young, Richard A, Hemann, Michael T
Published in Genes & development (15.05.2017)
Published in Genes & development (15.05.2017)
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Journal Article
A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth
Meacham, Corbin E, Lawton, Lee N, Soto-Feliciano, Yadira M, Pritchard, Justin R, Joughin, Brian A, Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T, Young, Richard A, Hemann, Michael T
Published in Genes & development (01.03.2015)
Published in Genes & development (01.03.2015)
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Journal Article
MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer
Zhu, Changyu, Soto-Feliciano, Yadira M, Morris, John P, Huang, Chun-Hao, Koche, Richard P, Ho, Yu-Jui, Banito, Ana, Chen, Chun-Wei, Shroff, Aditya, Tian, Sha, Livshits, Geulah, Chen, Chi-Chao, Fennell, Myles, Armstrong, Scott A, Allis, C David, Tschaharganeh, Darjus F, Lowe, Scott W
Published in eLife (01.06.2023)
Published in eLife (01.06.2023)
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Journal Article
Target identification reveals lanosterol synthase as a vulnerability in glioma
Phillips, Richard E., Yang, Yanhong, Smith, Ryan C., Thompson, Bonne M., Yamasaki, Tomoko, Soto-Feliciano, Yadira M., Funato, Kosuke, Liang, Yupu, Garcia-Bermudez, Javier, Wang, Xiaoshi, Garcia, Benjamin A., Yamasaki, Kazuhiko, McDonald, Jeffrey G., Birsoy, Kivanç, Tabar, Viviane, Allis, C. David
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
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Journal Article
Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration
Sánchez-Rivera, Francisco J, Ryan, Jeremy, Soto-Feliciano, Yadira M, Clare Beytagh, Mary, Xuan, Lucius, Feldser, David M, Hemann, Michael T, Zamudio, Jesse, Dimitrova, Nadya, Letai, Anthony, Jacks, Tyler
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (08.06.2021)
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Journal Article
A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition
Soto-Feliciano, Yadira M, Sánchez-Rivera, Francisco J, Perner, Florian, Barrows, Douglas W, Kastenhuber, Edward R, Ho, Yu-Jui, Carroll, Thomas, Xiong, Yijun, Anand, Disha, Soshnev, Alexey A, Gates, Leah, Beytagh, Mary Clare, Cheon, David, Gu, Shengqing, Liu, X Shirley, Krivtsov, Andrei V, Meneses, Maximiliano, de Stanchina, Elisa, Stone, Richard M, Armstrong, Scott A, Lowe, Scott W, Allis, C David
Published in Cancer discovery (09.01.2023)
Published in Cancer discovery (09.01.2023)
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Journal Article
Detection of High Explosives Using Reflection Absorption Infrared Spectroscopy with Fiber Coupled Grazing Angle Probe/FTIR
Primera-Pedrozo, Oliva M., Soto-Feliciano, Yadira M., Pacheco-Londoño, Leonardo C., Hernández-Rivera, Samuel P.
Published in Sensing and Imaging: An International Journal (01.06.2009)
Published in Sensing and Imaging: An International Journal (01.06.2009)
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Journal Article
Metabolic Reprogramming by Histone Deacetylase Inhibition Selectively Targets NRF2-activated tumors
Karagiannis, Dimitris, Wu, Warren, Li, Albert, Hayashi, Makiko, Chen, Xiao, Yip, Michaela, Mangipudy, Vaibhav, Xu, Xinjing, Sánchez-Rivera, Francisco J, Soto-Feliciano, Yadira M, Ye, Jiangbin, Papagiannakopoulos, Thales, Lu, Chao
Published in bioRxiv : the preprint server for biology (28.04.2023)
Published in bioRxiv : the preprint server for biology (28.04.2023)
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Journal Article
Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis
Zhuang, Xueqian, Wang, Qing, Joost, Simon, Ferrena, Alexander, Humphreys, David T, Li, Zhuxuan, Blum, Melissa, Bastl, Klavdija, Ding, Selena, Landais, Yuna, Zhan, Yingqian, Zhao, Yang, Chaligne, Ronan, Lee, Joo-Hyeon, Carrasco, Sebastian E, Bhanot, Umeshkumar K, Koche, Richard P, Bott, Matthew J, Katajisto, Pekka, Soto-Feliciano, Yadira M, Pisanic, Thomas, Thomas, Tiffany, Zheng, Deyou, Wong, Emily S, Tammela, Tuomas
Published in bioRxiv (28.06.2024)
Published in bioRxiv (28.06.2024)
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Journal Article
High Explosives Mixtures Detection Using Fiber Optics Coupled: Grazing Angle Probe/Fourier Transform Reflection Absorption Infrared Spectroscopy
Primera-Pedrozo, Oliva M., Soto-Feliciano, Yadira M., Pacheco-Londoño, Leonardo C., Hernández-Rivera, Samuel P.
Published in Sensing and Imaging: An International Journal (01.12.2008)
Published in Sensing and Imaging: An International Journal (01.12.2008)
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Journal Article
Targeting de novo purine synthesis pathway via ADSL depletion impairs liver cancer growth by perturbing mitochondrial function
Jiang, Tingting, Sánchez-Rivera, Francisco J., Soto-Feliciano, Yadira M., Yang, Qiyuan, Song, Chun-Qing, Bhuatkar, Arjun, Haynes, Cole M, Hemann, Michael T., Xue, Wen
Published in Hepatology (Baltimore, Md.) (01.07.2021)
Published in Hepatology (Baltimore, Md.) (01.07.2021)
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Journal Article
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Hoffmann, H-Heinrich, Schneider, William M, Sánchez-Rivera, Francisco J, Luna, Joseph M, Ashbrook, Alison W, Soto-Feliciano, Yadira M, Leal, Andrew A, Le Pen, Jérémie, Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F, Peace, Avery, Allis, C David, Lowe, Scott W, MacDonald, Margaret R, Poirier, John T, Rice, Charles M
Published in bioRxiv (11.09.2020)
Published in bioRxiv (11.09.2020)
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Abstract 2961: The level of mitochondrial apoptotic priming determines cell fate upon p53 restoration
Sánchez-Rivera, Francisco J., Ryan, Jeremy, Soto-Feliciano, Yadira M., Feldser, David M., Hemann, Michael T., Letai, Anthony, Jacks, Tyler
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract A44: The role of PHF6 in maintaining pre-B cell commitment in B-cell acute lymphoblastic leukemia
Soto-Feliciano, Yadira M., Bartlebaugh, Jordan ME, Liu, Yunpeng, Sánchez-Rivera, Francisco J., Weintraub, Abraham S., Bhutkar, Arjun, Jacks, Tyler E., Young, Richard A., Hemann, Michael T.
Published in Cancer research (Chicago, Ill.) (15.01.2016)
Published in Cancer research (Chicago, Ill.) (15.01.2016)
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Journal Article
A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition
Soto-Feliciano, Yadira M, Sanchez-Rivera, Francisco J, Perner, Florian, Barrows, Douglas W, Kastenhuber, Edward R, Yu-Jui, Ho, Carroll, Thomas, Xiong, Yijun, Anand, Disha, Soshnev, Alexey, Gates, Leah, Beytagh, Mary Clare, Cheon, David, Gu, Shengqing, X Shirley Liu, Krivtsov, Andrei V, Meneses, Maximiliano, De Stanchina, Elisa, Stone, Richard M, Armstrong, Scott A, Lowe, Scott W, Allis, C David
Published in bioRxiv (13.04.2022)
Published in bioRxiv (13.04.2022)
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Paper