Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs
Graziano, Giovanni, Stefanachi, Angela, Contino, Marialessandra, Prieto-Díaz, Rubén, Ligresti, Alessia, Kumar, Poulami, Scilimati, Antonio, Sotelo, Eddy, Leonetti, Francesco
Published in International journal of molecular sciences (01.04.2023)
Published in International journal of molecular sciences (01.04.2023)
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Three-Dimensional Printing in Catalysis: Combining 3D Heterogeneous Copper and Palladium Catalysts for Multicatalytic Multicomponent Reactions
Díaz-Marta, Antonio S, Tubío, Carmen R, Carbajales, Carlos, Fernández, Carmen, Escalante, Luz, Sotelo, Eddy, Guitián, Francisco, Barrio, V. Laura, Gil, Alvaro, Coelho, Alberto
Published in ACS catalysis (05.01.2018)
Published in ACS catalysis (05.01.2018)
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Identification of V6.51L as a selectivity hotspot in stereoselective A2B adenosine receptor antagonist recognition
Wang, Xuesong, Jespers, Willem, Prieto-Díaz, Rubén, Majellaro, Maria, IJzerman, Adriaan P., van Westen, Gerard J. P., Sotelo, Eddy, Heitman, Laura H., Gutiérrez-de-Terán, Hugo
Published in Scientific reports (08.07.2021)
Published in Scientific reports (08.07.2021)
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A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery
Navarro, Gemma, Sotelo, Eddy, Raïch, Iu, Loza, María Isabel, Brea, Jose, Majellaro, Maria
Published in Molecules (Basel, Switzerland) (01.12.2023)
Published in Molecules (Basel, Switzerland) (01.12.2023)
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Structure-Based Rational Design of Adenosine Receptor Ligands
Gutiérrez-de-Terán, Hugo, Sallander, Jessica, Sotelo, Eddy
Published in Current topics in medicinal chemistry (01.01.2017)
Published in Current topics in medicinal chemistry (01.01.2017)
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Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs
Gioé-Gallo, Claudia, Ortigueira, Sandra, Brea, José, Raïch, Iu, Azuaje, Jhonny, Paleo, M. Rita, Majellaro, Maria, Loza, María Isabel, Salas, Cristian O., García-Mera, Xerardo, Navarro, Gemma, Sotelo, Eddy
Published in Biomedicine & pharmacotherapy (01.08.2023)
Published in Biomedicine & pharmacotherapy (01.08.2023)
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Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents
Prieto-Díaz, Rubén, Fojo-Carballo, Hugo, Majellaro, Maria, Tandarić, Tana, Azuaje, Jhonny, Brea, José, Loza, María I., Barbazán, Jorge, Salort, Glòria, Chotalia, Meera, Rodríguez-Pampín, Iván, Mallo-Abreu, Ana, Rita Paleo, M., García-Mera, Xerardo, Ciruela, Francisco, Gutiérrez-de-Terán, Hugo, Sotelo, Eddy
Published in Biomedicine & pharmacotherapy (01.04.2024)
Published in Biomedicine & pharmacotherapy (01.04.2024)
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Deciphering conformational selectivity in the A2A adenosine G protein-coupled receptor by free energy simulations
Jespers, Willem, Heitman, Laura H, IJzerman, Adriaan P, Sotelo, Eddy, van Westen, Gerard J P, Åqvist, Johan, Gutiérrez-de-Terán, Hugo
Published in PLoS computational biology (01.11.2021)
Published in PLoS computational biology (01.11.2021)
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Gemcitabine-Vitamin E Prodrug-Loaded Micelles for Pancreatic Cancer Therapy
Pereira-Silva, Miguel, Miranda-Pastoriza, Darío, Diaz-Gomez, Luis, Sotelo, Eddy, Paiva-Santos, Ana Cláudia, Veiga, Francisco, Concheiro, Angel, Alvarez-Lorenzo, Carmen
Published in Pharmaceutics (01.01.2024)
Published in Pharmaceutics (01.01.2024)
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Integrated Ugi-Based Assembly of Functionally, Skeletally, and Stereochemically Diverse 1,4-Benzodiazepin-2-ones
Azuaje, Jhonny, Pérez-Rubio, José M, Yaziji, Vicente, El Maatougui, Abdelaziz, González-Gomez, José Carlos, Sánchez-Pedregal, Vı́ctor M, Navarro-Vázquez, Armando, Masaguer, Christian F, Teijeira, Marta, Sotelo, Eddy
Published in Journal of organic chemistry (06.02.2015)
Published in Journal of organic chemistry (06.02.2015)
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Multicomponent Assembly of Diverse Pyrazin-2(1H)‑one Chemotypes
Azuaje, Jhonny, El Maatougui, Abdelaziz, Pérez-Rubio, José M, Coelho, Alberto, Fernández, Franco, Sotelo, Eddy
Published in Journal of organic chemistry (03.05.2013)
Published in Journal of organic chemistry (03.05.2013)
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Fluorescence based HTS-compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
Tahk, Maris-Johanna, Laasfeld, Tõnis, Meriste, Elo, Brea, Jose, Loza, Maria Isabel, Majellaro, Maria, Contino, Marialessandra, Sotelo, Eddy, Rinken, Ago
Published in Frontiers in molecular biosciences (16.03.2023)
Published in Frontiers in molecular biosciences (16.03.2023)
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Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase
Bolognino, Isabella, Carrieri, Antonio, Purgatorio, Rosa, Catto, Marco, Caliandro, Rocco, Carrozzini, Benedetta, Belviso, Benny Danilo, Majellaro, Maria, Sotelo, Eddy, Cellamare, Saverio, Altomare, Cosimo Damiano
Published in Separations (01.01.2022)
Published in Separations (01.01.2022)
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Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid
Fernández-Dueñas, Víctor, Azuaje, Jhonny, Morató, Xavier, Cordobilla, Begoña, Domingo, Joan Carles, Sotelo, Eddy, Ciruela, Francisco
Published in Molecules (Basel, Switzerland) (27.02.2017)
Published in Molecules (Basel, Switzerland) (27.02.2017)
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Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases
Kalash, Leen, Val, Cristina, Azuaje, Jhonny, Loza, María I., Svensson, Fredrik, Zoufir, Azedine, Mervin, Lewis, Ladds, Graham, Brea, José, Glen, Robert, Sotelo, Eddy, Bender, Andreas
Published in Journal of cheminformatics (30.12.2017)
Published in Journal of cheminformatics (30.12.2017)
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A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models
Tay, Apple Hui Min, Prieto-Díaz, Rubén, Neo, Shiyong, Tong, Le, Chen, Xinsong, Carannante, Valentina, Önfelt, Björn, Hartman, Johan, Haglund, Felix, Majellaro, Maria, Azuaje, Jhonny, Garcia-Mera, Xerardo, Brea, Jose M, Loza, Maria I, Jespers, Willem, Gutierrez-de-Teran, Hugo, Sotelo, Eddy, Lundqvist, Andreas
Published in Journal for immunotherapy of cancer (01.05.2022)
Published in Journal for immunotherapy of cancer (01.05.2022)
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