Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts
Ayers, Jacob I, Riffe, Cara J, Sorrentino, Zachary A, Diamond, Jeffrey, Fagerli, Eric, Brooks, Mieu, Galaleldeen, Ahmad, Hart, P John, Giasson, Benoit I
Published in Journal of virology (15.09.2018)
Published in Journal of virology (15.09.2018)
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Journal Article
Neuronal tissue collection from intra-cranial instruments used in deep brain stimulation surgery for Parkinson’s disease with implications for study of alpha-synuclein
Sorrentino, Zachary A., Riklan, Joshua, Lloyd, Grace M., Lucke-Wold, Brandon P., Mampre, David, Quintin, Stephan, Zakare-Fagbamila, Rasheedat, Still, Megan, Chandra, Vyshak, Foote, Kelly D., Giasson, Benoit I., Hilliard, Justin D.
Published in Scientific reports (16.09.2024)
Published in Scientific reports (16.09.2024)
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Journal Article
Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies
Xia, Yuxing, Prokop, Stefan, Gorion, Kimberly-Marie M, Kim, Justin D, Sorrentino, Zachary A, Bell, Brach M, Manaois, Alyssa N, Chakrabarty, Paramita, Davies, Peter, Giasson, Benoit I
Published in Acta neuropathologica communications (22.06.2020)
Published in Acta neuropathologica communications (22.06.2020)
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Journal Article
Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity
Sorrentino, Zachary A, Brooks, Mieu M T, Hudson, 3rd, Vincent, Rutherford, Nicola J, Golde, Todd E, Giasson, Benoit I, Chakrabarty, Paramita
Published in Molecular neurodegeneration (29.05.2017)
Published in Molecular neurodegeneration (29.05.2017)
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Journal Article
Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration
Sorrentino, Zachary A., Xia, Yuxing, Funk, Cory, Riffe, Cara J., Rutherford, Nicola J., Ceballos Diaz, Carolina, Sacino, Amanda N., Price, Nathan D., Golde, Todd E., Giasson, Benoit I., Chakrabarty, Paramita
Published in Neurobiology of disease (01.12.2018)
Published in Neurobiology of disease (01.12.2018)
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Journal Article
Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression
Sorrentino, Zachary A, Goodwin, Marshall S, Riffe, Cara J, Dhillon, Jess-Karan S, Xia, Yuxing, Gorion, Kimberly-Marie, Vijayaraghavan, Niran, McFarland, Karen N, Golbe, Lawrence I, Yachnis, Anthony T, Giasson, Benoit I
Published in Acta neuropathologica communications (02.09.2019)
Published in Acta neuropathologica communications (02.09.2019)
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Journal Article
A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models
Lloyd, Grace M, Quintin, Stephan, Sorrentino, Zachary A, Gorion, Kimberly-Marie M, Bell, Brach M, Long, Brooke, Paterno, Giavanna, Giasson, Benoit I
Published in Acta neuropathologica communications (10.06.2024)
Published in Acta neuropathologica communications (10.06.2024)
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Journal Article
Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies
Hass, Ethan W, Sorrentino, Zachary A, Xia, Yuxing, Lloyd, Grace M, Trojanowski, John Q, Prokop, Stefan, Giasson, Benoit I
Published in Acta neuropathologica communications (28.08.2021)
Published in Acta neuropathologica communications (28.08.2021)
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Journal Article
Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy
Hass, Ethan W, Sorrentino, Zachary A, Lloyd, Grace M, McFarland, Nikolaus R, Prokop, Stefan, Giasson, Benoit I
Published in Acta neuropathologica communications (03.05.2021)
Published in Acta neuropathologica communications (03.05.2021)
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Journal Article
Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis
Lloyd, Grace M, Long, Brooke, Quintin, Stephan, Sorrentino, Zachary A, Gorion, Kimberly-Marie M, Bell, Brach M, Carrillo, Denise, Sullivan, Patrick, Borchelt, David, Giasson, Benoit I
Published in Acta neuropathologica communications (23.07.2023)
Published in Acta neuropathologica communications (23.07.2023)
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Journal Article
The emerging role of α-synuclein truncation in aggregation and disease
Sorrentino, Zachary A., Giasson, Benoit I.
Published in The Journal of biological chemistry (24.07.2020)
Published in The Journal of biological chemistry (24.07.2020)
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Journal Article
α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability
Dagra, Abeer, Miller, Douglas R., Lin, Min, Gopinath, Adithya, Shaerzadeh, Fatemeh, Harris, Sharonda, Sorrentino, Zachary A., Støier, Jonatan Fullerton, Velasco, Sophia, Azar, Janelle, Alonge, Adetola R., Lebowitz, Joseph J., Ulm, Brittany, Bu, Mengfei, Hansen, Carissa A., Urs, Nikhil, Giasson, Benoit I., Khoshbouei, Habibeh
Published in NPJ Parkinson's Disease (18.08.2021)
Published in NPJ Parkinson's Disease (18.08.2021)
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Journal Article
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies
Strang, Kevin H., Croft, Cara L., Sorrentino, Zachary A., Chakrabarty, Paramita, Golde, Todd E., Giasson, Benoit I.
Published in The Journal of biological chemistry (16.02.2018)
Published in The Journal of biological chemistry (16.02.2018)
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Journal Article
Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions
Sorrentino, Zachary A., Vijayaraghavan, Niran, Gorion, Kimberly-Marie, Riffe, Cara J., Strang, Kevin H., Caldwell, Jason, Giasson, Benoit I.
Published in The Journal of biological chemistry (07.12.2018)
Published in The Journal of biological chemistry (07.12.2018)
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Journal Article
Carboxy‐terminal truncations of mouse α‐synuclein alter aggregation and prion‐like seeding
Sorrentino, Zachary A., Xia, Yuxing, Gorion, Kimberly‐Marie, Hass, Ethan, Giasson, Benoit I.
Published in FEBS letters (01.04.2020)
Published in FEBS letters (01.04.2020)
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Journal Article
Headache persisting after aneurysmal subarachnoid hemorrhage: A narrative review of pathophysiology and therapeutic strategies
Sorrentino, Zachary A., Laurent, Dimitri, Hernandez, Jairo, Davidson, Caroline, Small, Coulter, Dodd, William, Lucke‐Wold, Brandon
Published in Headache (01.10.2022)
Published in Headache (01.10.2022)
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Journal Article
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential
Ferreira, Nelson, Gram, Hjalte, Sorrentino, Zachary A., Gregersen, Emil, Schmidt, Sissel Ida, Reimer, Lasse, Betzer, Cristine, Perez-Gozalbo, Clara, Beltoja, Marjo, Nagaraj, Madhu, Wang, Jie, Nowak, Jan S., Dong, Mingdong, Willén, Katarina, Cholak, Ersoy, Bjerregaard-Andersen, Kaare, Mendez, Nicolas, Rabadia, Prakruti, Shahnawaz, Mohammad, Soto, Claudio, Otzen, Daniel E., Akbey, Ümit, Meyer, Morten, Giasson, Benoit I., Romero-Ramos, Marina, Jensen, Poul Henning
Published in Acta neuropathologica (01.07.2021)
Published in Acta neuropathologica (01.07.2021)
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Journal Article
Interventional Treatment of Symptomatic Vasospasm in the Setting of Traumatic Brain Injury: A Systematic Review of Reported Cases
Sorrentino, Zachary A., Lucke-Wold, Brandon P., Laurent, Dimitri, Quintin, Stephan S., Hoh, Brian L.
Published in World neurosurgery (01.03.2024)
Published in World neurosurgery (01.03.2024)
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Journal Article