ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia
Sucha, Simona, Sorf, Ales, Svoren, Martin, Vagiannis, Dimitrios, Ahmed, Fahda, Visek, Benjamin, Ceckova, Martina
Published in Biomedicine & pharmacotherapy (01.06.2022)
Published in Biomedicine & pharmacotherapy (01.06.2022)
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S-(4-Nitrobenzyl)-6-thioinosine (NBMPR) is Not a Selective Inhibitor of Equilibrative Nucleoside Transporters but Also Blocks Efflux Activity of Breast Cancer Resistance Protein
Karbanova, Sara, Sorf, Ales, Jiraskova, Lucie, Lalinska, Anezka, Ptackova, Zuzana, Staud, Frantisek, Cerveny, Lukas
Published in Pharmaceutical research (01.03.2020)
Published in Pharmaceutical research (01.03.2020)
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In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
Soukup, Ondrej, Korabecny, Jan, Malinak, David, Nepovimova, Eugenie, Pham, Ngoc L, Musilek, Kamil, Hrabinova, Martina, Hepnarova, Vendula, Dolezal, Rafael, Pavek, Petr, Jost, Petr, Kobrlova, Tereza, Jankockova, Jana, Gorecki, Lukas, Psotka, Miroslav, Nguyen, Thuy D, Box, Karl, Outhwaite, Breeze, Ceckova, Martina, Sorf, Ales, Jun, Daniel, Kuca, Kamil
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.05.2018)
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.05.2018)
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Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro
Sorf, Ales, Hofman, Jakub, Kučera, Radim, Staud, Frantisek, Ceckova, Martina
Published in Biochemical pharmacology (01.08.2018)
Published in Biochemical pharmacology (01.08.2018)
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Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics
Tupova, Lenka, Ceckova, Martina, Ambrus, Csilla, Sorf, Ales, Ptackova, Zuzana, Gaborik, Zsuzsanna, Staud, Frantisek
Published in Drug metabolism and disposition (01.09.2019)
Published in Drug metabolism and disposition (01.09.2019)
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Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity
Pulkrabkova, Lenka, Muckova, Lubica, Hrabinova, Martina, Sorf, Ales, Kobrlova, Tereza, Jost, Petr, Bezdekova, Dagmar, Korabecny, Jan, Jun, Daniel, Soukup, Ondrej
Published in Archives of toxicology (01.08.2023)
Published in Archives of toxicology (01.08.2023)
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Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters
Sorf, Ales, Novotna, Eva, Hofman, Jakub, Morell, Anselm, Staud, Frantisek, Wsol, Vladimir, Ceckova, Martina
Published in Biochemical pharmacology (01.05.2019)
Published in Biochemical pharmacology (01.05.2019)
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Journal Article
S- is Not a Selective Inhibitor of Equilibrative Nucleoside Transporters but Also Blocks Efflux Activity of Breast Cancer Resistance Protein
Karbanova, Sara, Sorf, Ales, Jiraskova, Lucie, Lalinska, Anezka, Ptackova, Zuzana, Staud, Frantisek, Cerveny, Lukas
Published in Pharmaceutical research (01.03.2020)
Published in Pharmaceutical research (01.03.2020)
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Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance
Hofman, Jakub, Sorf, Ales, Vagiannis, Dimitrios, Sucha, Simona, Novotna, Eva, Kammerer, Sarah, Küpper, Jan-Heiner, Ceckova, Martina, Staud, Frantisek
Published in Drug metabolism and disposition (01.07.2019)
Published in Drug metabolism and disposition (01.07.2019)
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Multifunctional, fluorene‐based modulator of cholinergic and GABAergic neurotransmission as a novel drug candidate for palliative treatment of Alzheimer’s disease
Panek, Dawid, Pasieka, Anna, Jończyk, Jakub Józef, Gawlińska, Milena, Zaręba, Paula, Siwek, Agata, Wolak, Małgorzata, Mordyl, Barbara, Głuch-Lutwin, Monika, Latacz, Gniewomir, Brazzolotto, Xavier, Chantegreil, Fabien, Nachon, Florian, Zdarova Karasova, Jana, Pejchal, Jaroslav, Mzik, Martin, Sestak, Vit, Prchal, Lukas, Odvarkova, Jitka, Soukup, Ondrej, Korabecny, Jan, Sorf, Ales, Hamsikova, Marie, Zemanova, Lucie, Muckova, Lubica, Vánova, Nela, Dryja, Pola, Sałat, Kinga, Höfner, Georg, Wanner, Klaus, Więckowska, Anna, Malawska, Barbara
Published in Angewandte Chemie International Edition (11.11.2024)
Published in Angewandte Chemie International Edition (11.11.2024)
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Brivanib Exhibits Potential for Pharmacokinetic Drug–Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes
Hofman, Jakub, Sorf, Ales, Vagiannis, Dimitrios, Sucha, Simona, Kammerer, Sarah, Küpper, Jan-Heiner, Chen, Si, Guo, Lei, Ceckova, Martina, Staud, Frantisek
Published in Molecular pharmaceutics (04.11.2019)
Published in Molecular pharmaceutics (04.11.2019)
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Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors
Sorf, Ales, Sucha, Simona, Morell, Anselm, Novotna, Eva, Staud, Frantisek, Zavrelova, Alzbeta, Visek, Benjamin, Wsol, Vladimir, Ceckova, Martina
Published in Cancers (16.06.2020)
Published in Cancers (16.06.2020)
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Carltonine-derived compounds for targeted butyrylcholinesterase inhibition
Pidany, Filip, Kroustkova, Jana, Jenco, Jaroslav, Breiterova, Katerina Hradiska, Muckova, Lubica, Novakova, Lucie, Kunes, Jiri, Fibigar, Jakub, Kucera, Tomas, Novak, Martin, Sorf, Ales, Hrabinova, Martina, Pulkrabkova, Lenka, Janousek, Jiri, Soukup, Ondrej, Jun, Daniel, Korabecny, Jan, Cahlikova, Lucie
Published in MedChemComm (22.05.2024)
Published in MedChemComm (22.05.2024)
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Journal Article
Multifunctional, fluorene‐based modulator of cholinergic and GABAergic neurotransmission as a novel drug candidate for palliative treatment of Alzheimer’s disease
Panek, Dawid, Pasieka, Anna, Jończyk, Jakub Józef, Gawlińska, Milena, Zaręba, Paula, Siwek, Agata, Wolak, Małgorzata, Mordyl, Barbara, Głuch-Lutwin, Monika, Latacz, Gniewomir, Brazzolotto, Xavier, Chantegreil, Fabien, Nachon, Florian, Zdarova Karasova, Jana, Pejchal, Jaroslav, Mzik, Martin, Sestak, Vit, Prchal, Lukas, Odvarkova, Jitka, Soukup, Ondrej, Korabecny, Jan, Sorf, Ales, Hamsikova, Marie, Zemanova, Lucie, Muckova, Lubica, Vánova, Nela, Dryja, Pola, Sałat, Kinga, Höfner, Georg, Wanner, Klaus, Więckowska, Anna, Malawska, Barbara
Published in Angewandte Chemie (11.11.2024)
Published in Angewandte Chemie (11.11.2024)
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