Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex
Bussiere, Dirksen E., Xie, Lili, Srinivas, Honnappa, Shu, Wei, Burke, Ashley, Be, Celine, Zhao, Junping, Godbole, Adarsh, King, Dan, Karki, Rajeshri G., Hornak, Viktor, Xu, Fangmin, Cobb, Jennifer, Carte, Nathalie, Frank, Andreas O., Frommlet, Alexandra, Graff, Patrick, Knapp, Mark, Fazal, Aleem, Okram, Barun, Jiang, Songchun, Michellys, Pierre-Yves, Beckwith, Rohan, Voshol, Hans, Wiesmann, Christian, Solomon, Jonathan M., Paulk, Joshiawa
Published in Nature chemical biology (01.01.2020)
Published in Nature chemical biology (01.01.2020)
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Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High Throughput Screening Assay. 4. Structure–Activity Relationships of N-Alkyl Substituted Pyrrole Fused at the 7,8-Positions
Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Crogan-Grundy, Candace, Labreque, Denis, Bubenick, Monica, Attardo, Giorgio, Denis, Real, Lamothe, Serge, Gourdeau, Henriette, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.02.2008)
Published in Journal of medicinal chemistry (14.02.2008)
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Discovery of N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration
Sirisoma, Nilantha, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Willardsen, J. Adam, Anderson, Mark B, Mather, Gary, Pleiman, Christopher M, Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (23.04.2009)
Published in Journal of medicinal chemistry (23.04.2009)
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Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex
Bussiere, Dirksen E., Xie, Lili, Srinivas, Honnappa, Shu, Wei, Burke, Ashley, Be, Celine, Zhao, Junping, Godbole, Adarsh, King, Dan, Karki, Rajeshri G., Hornak, Viktor, Xu, Fangmin, Cobb, Jennifer, Carte, Nathalie, Frank, Andreas O., Frommlet, Alexandra, Graff, Patrick, Knapp, Mark, Fazal, Aleem, Okram, Barun, Jiang, Songchun, Michellys, Pierre-Yves, Beckwith, Rohan, Voshol, Hans, Wiesmann, Christian, Solomon, Jonathan M., Paulk, Joshiawa
Published in Nature chemical biology (01.03.2020)
Published in Nature chemical biology (01.03.2020)
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Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High-Throughput Screening Assay. 3. Structure−Activity Relationships of Fused Rings at the 7,8-Positions
Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Zhao, Jianghong, Crogan-Grundy, Candace, Xu, Lifen, Lamothe, Serge, Gourdeau, Henriette, Denis, Réal, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.06.2007)
Published in Journal of medicinal chemistry (14.06.2007)
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Journal Article
Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-based High-Throughput Screening Assay. 1. Structure−Activity Relationships of the 4-Aryl Group
Kemnitzer, William, Drewe, John, Jiang, Songchun, Zhang, Hong, Wang, Yan, Zhao, Jianghong, Jia, Shaojuan, Herich, John, Labreque, Denis, Storer, Richard, Meerovitch, Karen, Bouffard, David, Rej, Rabindra, Denis, Real, Blais, Charles, Lamothe, Serge, Attardo, Giorgio, Gourdeau, Henriette, Tseng, Ben, Kasibhatla, Shailaja, Cai, Sui Xiong
Published in Journal of medicinal chemistry (02.12.2004)
Published in Journal of medicinal chemistry (02.12.2004)
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Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions
KEMNITZER, William, KASIBHATLA, Shailaja, VAILLANCOURT, Louis, CHARRON, Sylvie, DODD, Jennifer, ATTARDO, Giorgio, LABRECQUE, Denis, LAMOTHE, Serge, GOURDEAU, Henriette, TSENG, Ben, DREWE, John, SUI XIONG CAI, SONGCHUN JIANG, HONG ZHANG, JIANGHONG ZHAO, SHAOJUAN JIA, LIFEN XU, CROGAN-GRUNDY, Candace, DENIS, Réal, BARRIAULT, Nancy
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
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A Role for Transferrin Receptor in Triggering Apoptosis When Targeted with Gambogic Acid
Kasibhatla, Shailaja, Jessen, Katayoun A, Maliartchouk, Sergei, Wang, Jean Yu, English, Nicole M, Drewe, John, Qiu, Ling, Archer, Shannon P, Ponce, Anthony E, Sirisoma, Nilantha, Jiang, Songchun, Zhang, Han-Zhong, Gehlsen, Kurt R, Cai, Sui Xiong, Green, Douglas R, Tseng, Ben
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2005)
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Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based HTS assay. Part 5: Modifications of the 2-and 3-positions
KEMNITZER, William, SONGCHUN JIANG, GOURDEAU, Henriette, TSENG, Ben, DREWE, John, SUI XIONG CAI, YAN WANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, BUBENIK, Monica, LABRECQUE, Denis, DENIS, Real, LAMOTHE, Serge, ATTARDO, Giorgio
Published in Bioorganic & medicinal chemistry (15.01.2008)
Published in Bioorganic & medicinal chemistry (15.01.2008)
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Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell-and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1-and 3-positions
KEMNITZER, William, KUEMMERLE, Jared, SONGCHUN JIANG, ZHANG, Han-Zhong, SIRISOMA, Nilantha, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, TSENG, Ben, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry letters (01.12.2008)
Published in Bioorganic & medicinal chemistry letters (01.12.2008)
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Discovery of 1-benzoyl-3-cyanopyrrolo[1,2- a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure–activity relationships of the 4-, 5-, 6-, 7- and 8-positions
Kemnitzer, William, Kuemmerle, Jared, Jiang, Songchun, Sirisoma, Nilantha, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
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Discovery of 2-Chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity
Sirisoma, Nilantha, Kasibhatla, Shailaja, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Willardsen, J. Adam, Anderson, Mark B, Baichwal, Vijay, Mather, Gary G, Jessing, Kevin, Hussain, Raouf, Hoang, Khanh, Pleiman, Christopher M, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
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Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure–activity relationship of the quinazoline ring
Sirisoma, Nilantha, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Adam Willardsen, J., Anderson, Mark B., Mather, Gary, Pleiman, Christopher M., Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
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Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell-and caspase-based high-throughput screening assay
KEMNITZER, William, SONGCHUN JIANG, TSENG, Ben, DREWE, John, SUI XIONG CAI, HONG ZHANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, BLAIS, Charles, ATTARDO, Giorgio, DENIS, Real, LAMOTHE, Serge, GOURDEAU, Henriette
Published in Bioorganic & medicinal chemistry letters (15.10.2008)
Published in Bioorganic & medicinal chemistry letters (15.10.2008)
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Synthesis of caged 2,3,3a,7a-tetrahydro-3,6-methanobenzofuran-7(6 H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid
Kuemmerle, Jared, Jiang, Songchun, Tseng, Ben, Kasibhatla, Shailaja, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry (15.04.2008)
Published in Bioorganic & medicinal chemistry (15.04.2008)
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Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure–activity relationships of the carboxamide group
Kemnitzer, William, Sirisoma, Nilantha, Nguyen, Bao, Jiang, Songchun, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
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Journal Article
Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 9-oxo-9H-fluorene ring
KEMNITZER, William, SIRISOMA, Nilantha, SONGCHUN JIANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, TSENG, Ben, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl- N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay
Jiang, Songchun, Crogan-Grundy, Candace, Drewe, John, Tseng, Ben, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry (01.11.2008)
Published in Bioorganic & medicinal chemistry (01.11.2008)
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