Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics
Morita, Kiyomi, Wang, Feng, Jahn, Katharina, Hu, Tianyuan, Tanaka, Tomoyuki, Sasaki, Yuya, Kuipers, Jack, Loghavi, Sanam, Wang, Sa A., Yan, Yuanqing, Furudate, Ken, Matthews, Jairo, Little, Latasha, Gumbs, Curtis, Zhang, Jianhua, Song, Xingzhi, Thompson, Erika, Patel, Keyur P., Bueso-Ramos, Carlos E., DiNardo, Courtney D., Ravandi, Farhad, Jabbour, Elias, Andreeff, Michael, Cortes, Jorge, Bhalla, Kapil, Garcia-Manero, Guillermo, Kantarjian, Hagop, Konopleva, Marina, Nakada, Daisuke, Navin, Nicholas, Beerenwinkel, Niko, Futreal, P. Andrew, Takahashi, Koichi
Published in Nature communications (21.10.2020)
Published in Nature communications (21.10.2020)
Get full text
Journal Article
Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia
Wang, Feng, Morita, Kiyomi, DiNardo, Courtney D., Furudate, Ken, Tanaka, Tomoyuki, Yan, Yuanqing, Patel, Keyur P., MacBeth, Kyle J., Wu, Bin, Liu, Guowen, Frattini, Mark, Matthews, Jairo A., Little, Latasha D., Gumbs, Curtis, Song, Xingzhi, Zhang, Jianhua, Thompson, Erika J., Kadia, Tapan M., Garcia-Manero, Guillermo, Jabbour, Elias, Ravandi, Farhad, Bhalla, Kapil N., Konopleva, Marina, Kantarjian, Hagop M., Andrew Futreal, P., Takahashi, Koichi
Published in Nature communications (10.05.2021)
Published in Nature communications (10.05.2021)
Get full text
Journal Article
Systematic analysis of telomere length and somatic alterations in 31 cancer types
Barthel, Floris P, Wei, Wei, Tang, Ming, Martinez-Ledesma, Emmanuel, Hu, Xin, Amin, Samirkumar B, Akdemir, Kadir C, Seth, Sahil, Song, Xingzhi, Wang, Qianghu, Lichtenberg, Tara, Hu, Jian, Zhang, Jianhua, Zheng, Siyuan, Verhaak, Roel G W
Published in Nature genetics (01.03.2017)
Published in Nature genetics (01.03.2017)
Get full text
Journal Article
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations
Zhang, Yiqun, Kwok-Shing Ng, Patrick, Kucherlapati, Melanie, Chen, Fengju, Liu, Yuexin, Tsang, Yiu Huen, de Velasco, Guillermo, Jeong, Kang Jin, Akbani, Rehan, Hadjipanayis, Angela, Pantazi, Angeliki, Bristow, Christopher A., Lee, Eunjung, Mahadeshwar, Harshad S., Tang, Jiabin, Zhang, Jianhua, Yang, Lixing, Seth, Sahil, Lee, Semin, Ren, Xiaojia, Song, Xingzhi, Sun, Huandong, Seidman, Jonathan, Luquette, Lovelace J., Xi, Ruibin, Chin, Lynda, Protopopov, Alexei, Westbrook, Thomas F., Shelley, Carl Simon, Choueiri, Toni K., Ittmann, Michael, Van Waes, Carter, Weinstein, John N., Liang, Han, Henske, Elizabeth P., Godwin, Andrew K., Park, Peter J., Kucherlapati, Raju, Scott, Kenneth L., Mills, Gordon B., Kwiatkowski, David J., Creighton, Chad J.
Published in Cancer cell (12.06.2017)
Published in Cancer cell (12.06.2017)
Get full text
Journal Article
Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma
Wang, Ruiping, Dang, Minghao, Harada, Kazuto, Han, Guangchun, Wang, Fang, Pool Pizzi, Melissa, Zhao, Meina, Tatlonghari, Ghia, Zhang, Shaojun, Hao, Dapeng, Lu, Yang, Zhao, Shuangtao, Badgwell, Brian D., Blum Murphy, Mariela, Shanbhag, Namita, Estrella, Jeannelyn S., Roy-Chowdhuri, Sinchita, Abdelhakeem, Ahmed Adel Fouad, Wang, Yuanxin, Peng, Guang, Hanash, Samir, Calin, George A., Song, Xingzhi, Chu, Yanshuo, Zhang, Jianhua, Li, Mingyao, Chen, Ken, Lazar, Alexander J., Futreal, Andrew, Song, Shumei, Ajani, Jaffer A., Wang, Linghua
Published in Nature medicine (01.01.2021)
Published in Nature medicine (01.01.2021)
Get full text
Journal Article
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
Zhang, Jianjun, Fujimoto, Junya, Zhang, Jianhua, Wedge, David C., Song, Xingzhi, Zhang, Jiexin, Seth, Sahil, Chow, Chi-Wan, Cao, Yu, Gumbs, Curtis, Gold, Kathryn A., Kalhor, Neda, Little, Latasha, Mahadeshwar, Harshad, Moran, Cesar, Protopopov, Alexei, Sun, Huandong, Tang, Jiabin, Wu, Xifeng, Ye, Yuanqing, William, William N., Lee, J. Jack, Heymach, John V., Hong, Waun Ki, Swisher, Stephen, Wistuba, Ignacio I., Futreal, P. Andrew
Published in Science (American Association for the Advancement of Science) (10.10.2014)
Published in Science (American Association for the Advancement of Science) (10.10.2014)
Get full text
Journal Article
Comprehensive T cell repertoire characterization of non-small cell lung cancer
Reuben, Alexandre, Zhang, Jiexin, Chiou, Shin-Heng, Gittelman, Rachel M., Li, Jun, Lee, Won-Chul, Fujimoto, Junya, Behrens, Carmen, Liu, Xiaoke, Wang, Feng, Quek, Kelly, Wang, Chunlin, Kheradmand, Farrah, Chen, Runzhe, Chow, Chi-Wan, Lin, Heather, Bernatchez, Chantale, Jalali, Ali, Hu, Xin, Wu, Chang-Jiun, Eterovic, Agda Karina, Parra, Edwin Roger, Yusko, Erik, Emerson, Ryan, Benzeno, Sharon, Vignali, Marissa, Wu, Xifeng, Ye, Yuanqing, Little, Latasha D., Gumbs, Curtis, Mao, Xizeng, Song, Xingzhi, Tippen, Samantha, Thornton, Rebecca L., Cascone, Tina, Snyder, Alexandra, Wargo, Jennifer A., Herbst, Roy, Swisher, Stephen, Kadara, Humam, Moran, Cesar, Kalhor, Neda, Zhang, Jianhua, Scheet, Paul, Vaporciyan, Ara A., Sepesi, Boris, Gibbons, Don L., Robins, Harlan, Hwu, Patrick, Heymach, John V., Sharma, Padmanee, Allison, James P., Baladandayuthapani, Veera, Lee, Jack J., Davis, Mark M., Wistuba, Ignacio I., Futreal, P. Andrew, Zhang, Jianjun
Published in Nature communications (30.01.2020)
Published in Nature communications (30.01.2020)
Get full text
Journal Article
Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma
Zhang, Liang, Yao, Yixin, Zhang, Shaojun, Liu, Yang, Guo, Hui, Ahmed, Makhdum, Bell, Taylor, Zhang, Hui, Han, Guangchun, Lorence, Elizabeth, Badillo, Maria, Zhou, Shouhao, Sun, Yuting, Di Francesco, M Emilia, Feng, Ningping, Haun, Randy, Lan, Renny, Mackintosh, Samuel G, Mao, Xizeng, Song, Xingzhi, Zhang, Jianhua, Pham, Lan V, Lorenzi, Philip L, Marszalek, Joseph, Heffernan, Tim, Draetta, Giulio, Jones, Philip, Futreal, Andrew, Nomie, Krystle, Wang, Linghua, Wang, Michael
Published in Science translational medicine (08.05.2019)
Published in Science translational medicine (08.05.2019)
Get more information
Journal Article
Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia
Morita, Kiyomi, Kantarjian, Hagop M, Wang, Feng, Yan, Yuanqing, Bueso-Ramos, Carlos, Sasaki, Koji, Issa, Ghayas C, Wang, Sa, Jorgensen, Jeffrey, Song, Xingzhi, Zhang, Jianhua, Tippen, Samantha, Thornton, Rebecca, Coyle, Marcus, Little, Latasha, Gumbs, Curtis, Pemmaraju, Naveen, Daver, Naval, DiNardo, Courtney D, Konopleva, Marina, Andreeff, Michael, Ravandi, Farhad, Cortes, Jorge E, Kadia, Tapan, Jabbour, Elias, Garcia-Manero, Guillermo, Patel, Keyur P, Futreal, P Andrew, Takahashi, Koichi
Published in Journal of clinical oncology (20.06.2018)
Published in Journal of clinical oncology (20.06.2018)
Get full text
Journal Article
Oncogenic Kras drives invasion and maintains metastases in colorectal cancer
Boutin, Adam T, Liao, Wen-Ting, Wang, Melody, Hwang, Soyoon Sarah, Karpinets, Tatiana V, Cheung, Hannah, Chu, Gerald C, Jiang, Shan, Hu, Jian, Chang, Kyle, Vilar, Eduardo, Song, Xingzhi, Zhang, Jianhua, Kopetz, Scott, Futreal, Andrew, Wang, Y Alan, Kwong, Lawrence N, DePinho, Ronald A
Published in Genes & development (15.02.2017)
Published in Genes & development (15.02.2017)
Get full text
Journal Article
Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets
Ferrarotto, Renata, Mitani, Yoshitsugu, McGrail, Daniel J, Li, Kaiyi, Karpinets, Tatiana V, Bell, Diana, Frank, Steven J, Song, Xingzhi, Kupferman, Michael E, Liu, Bin, Lee, J Jack, Glisson, Bonnie S, Zhang, Jianhua, Aster, Jon C, Lin, Shiaw-Yih, Futreal, P Andrew, Heymach, John V, El-Naggar, Adel K
Published in Clinical cancer research (01.02.2021)
Published in Clinical cancer research (01.02.2021)
Get full text
Journal Article
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Behjati, Sam, Tarpey, Patrick S, Sheldon, Helen, Martincorena, Inigo, Van Loo, Peter, Gundem, Gunes, Wedge, David C, Ramakrishna, Manasa, Cooke, Susanna L, Pillay, Nischalan, Vollan, Hans Kristian M, Papaemmanuil, Elli, Koss, Hans, Bunney, Tom D, Hardy, Claire, Joseph, Olivia R, Martin, Sancha, Mudie, Laura, Butler, Adam, Teague, Jon W, Patil, Meena, Steers, Graham, Cao, Yu, Gumbs, Curtis, Ingram, Davis, Lazar, Alexander J, Little, Latasha, Mahadeshwar, Harshad, Protopopov, Alexei, Al Sannaa, Ghadah A, Seth, Sahil, Song, Xingzhi, Tang, Jiabin, Zhang, Jianhua, Ravi, Vinod, Torres, Keila E, Khatri, Bhavisha, Halai, Dina, Roxanis, Ioannis, Baumhoer, Daniel, Tirabosco, Roberto, Amary, M Fernanda, Boshoff, Chris, McDermott, Ultan, Katan, Matilda, Stratton, Michael R, Futreal, P Andrew, Flanagan, Adrienne M, Harris, Adrian, Campbell, Peter J
Published in Nature genetics (01.04.2014)
Published in Nature genetics (01.04.2014)
Get full text
Journal Article
Mechanisms of nuclear content loading to exosomes
Yokoi, Akira, Villar-Prados, Alejandro, Oliphint, Paul Allen, Zhang, Jianhua, Song, Xingzhi, De Hoff, Peter, Morey, Robert, Liu, Jinsong, Roszik, Jason, Clise-Dwyer, Karen, Burks, Jared K, O'Halloran, Theresa J, Laurent, Louise C, Sood, Anil K
Published in Science advances (01.11.2019)
Published in Science advances (01.11.2019)
Get full text
Journal Article
Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
Hu, Xin, Fujimoto, Junya, Ying, Lisha, Fukuoka, Junya, Ashizawa, Kazuto, Sun, Wenyong, Reuben, Alexandre, Chow, Chi-Wan, McGranahan, Nicholas, Chen, Runzhe, Hu, Jinlin, Godoy, Myrna C., Tabata, Kazuhiro, Kuroda, Kishio, Shi, Lei, Li, Jun, Behrens, Carmen, Parra, Edwin Roger, Little, Latasha D., Gumbs, Curtis, Mao, Xizeng, Song, Xingzhi, Tippen, Samantha, Thornton, Rebecca L., Kadara, Humam, Scheet, Paul, Roarty, Emily, Ostrin, Edwin Justin, Wang, Xu, Carter, Brett W., Antonoff, Mara B., Zhang, Jianhua, Vaporciyan, Ara A., Pass, Harvey, Swisher, Stephen G., Heymach, John V., Lee, J. Jack, Wistuba, Ignacio I., Hong, Waun Ki, Futreal, P. Andrew, Su, Dan, Zhang, Jianjun
Published in Nature communications (05.07.2019)
Published in Nature communications (05.07.2019)
Get full text
Journal Article
Genomic heterogeneity of multiple synchronous lung cancer
Liu, Yu, Zhang, Jianjun, Li, Lin, Yin, Guangliang, Zhang, Jianhua, Zheng, Shan, Cheung, Hannah, Wu, Ning, Lu, Ning, Mao, Xizeng, Yang, Longhai, Zhang, Jiexin, Zhang, Li, Seth, Sahil, Chen, Huang, Song, Xingzhi, Liu, Kan, Xie, Yongqiang, Zhou, Lina, Zhao, Chuanduo, Han, Naijun, Chen, Wenting, Zhang, Susu, Chen, Longyun, Cai, Wenjun, Li, Lin, Shen, Miaozhong, Xu, Ningzhi, Cheng, Shujun, Yang, Huanming, Lee, J. Jack, Correa, Arlene, Fujimoto, Junya, Behrens, Carmen, Chow, Chi-Wan, William, William N., Heymach, John V., Hong, Waun Ki, Swisher, Stephen, Wistuba, Ignacio I., Wang, Jun, Lin, Dongmei, Liu, Xiangyang, Futreal, P. Andrew, Gao, Yanning
Published in Nature communications (21.10.2016)
Published in Nature communications (21.10.2016)
Get full text
Journal Article
The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics
Tang, Ming, Abbas, Hussein A., Negrao, Marcelo V., Ramineni, Maheshwari, Hu, Xin, Hubert, Shawna Marie, Fujimoto, Junya, Reuben, Alexandre, Varghese, Susan, Zhang, Jianhua, Li, Jun, Chow, Chi-Wan, Mao, Xizeng, Song, Xingzhi, Lee, Won-Chul, Wu, Jia, Little, Latasha, Gumbs, Curtis, Behrens, Carmen, Moran, Cesar, Weissferdt, Annikka, Lee, J. Jack, Sepesi, Boris, Swisher, Stephen, Cheng, Chao, Kurie, Jonathan, Gibbons, Don, Heymach, John V., Wistuba, Ignacio I., Futreal, P. Andrew, Kalhor, Neda, Zhang, Jianjun
Published in Nature communications (06.12.2021)
Published in Nature communications (06.12.2021)
Get full text
Journal Article
Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma
Zhang, Shaojun, Jiang, Vivian Changying, Han, Guangchun, Hao, Dapeng, Lian, Junwei, Liu, Yang, Cai, Qingsong, Zhang, Rongjia, McIntosh, Joseph, Wang, Ruiping, Dang, Minghao, Dai, Enyu, Wang, Yuanxin, Santos, David, Badillo, Maria, Leeming, Angela, Chen, Zhihong, Hartig, Kimberly, Bigcal, John, Zhou, Jia, Kanagal-Shamanna, Rashmi, Ok, Chi Young, Lee, Hun, Steiner, Raphael E., Zhang, Jianhua, Song, Xingzhi, Nair, Ranjit, Ahmed, Sairah, Rodriquez, Alma, Thirumurthi, Selvi, Jain, Preetesh, Wagner-Bartak, Nicolaus, Hill, Holly, Nomie, Krystle, Flowers, Christopher, Futreal, Andrew, Wang, Linghua, Wang, Michael
Published in Nature communications (17.05.2021)
Published in Nature communications (17.05.2021)
Get full text
Journal Article
Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis
Fukumura, Kazutaka, Malgulwar, Prit Benny, Fischer, Grant M., Hu, Xiaoding, Mao, Xizeng, Song, Xingzhi, Hernandez, Sharia D., Zhang, Xiang H.-F., Zhang, Jianhua, Parra, Edwin Roger, Yu, Dihua, Debeb, Bisrat G., Davies, Michael A., Huse, Jason T.
Published in Acta neuropathologica (01.02.2021)
Published in Acta neuropathologica (01.02.2021)
Get full text
Journal Article
Direct selection of human genomic loci by microarray hybridization
Albert, Thomas J, Gibbs, Richard A, Molla, Michael N, Muzny, Donna M, Nazareth, Lynne, Wheeler, David, Song, Xingzhi, Richmond, Todd A, Middle, Chris M, Rodesch, Matthew J, Packard, Charles J, Weinstock, George M
Published in Nature methods (01.11.2007)
Published in Nature methods (01.11.2007)
Get full text
Journal Article
Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer
Lee, Sanghoon, Zhao, Li, Rojas, Christine, Bateman, Nicholas W., Yao, Hui, Lara, Olivia D., Celestino, Joseph, Morgan, Margaret B., Nguyen, Tri V., Conrads, Kelly A., Rangel, Kelly M., Dood, Robert L., Hajek, Richard A., Fawcett, Gloria L., Chu, Randy A., Wilson, Katlin, Loffredo, Jeremy L., Viollet, Coralie, Jazaeri, Amir A., Dalgard, Clifton L., Mao, Xizeng, Song, Xingzhi, Zhou, Ming, Hood, Brian L., Banskota, Nirad, Wilkerson, Matthew D., Te, Jerez, Soltis, Anthony R., Roman, Kristin, Dunn, Andrew, Cordover, David, Eterovic, Agda Karina, Liu, Jinsong, Burks, Jared K., Baggerly, Keith A., Fleming, Nicole D., Lu, Karen H., Westin, Shannon N., Coleman, Robert L., Mills, Gordon B., Casablanca, Yovanni, Zhang, Jianhua, Conrads, Thomas P., Maxwell, George L., Futreal, P. Andrew, Sood, Anil K.
Published in Cell reports (Cambridge) (14.04.2020)
Published in Cell reports (Cambridge) (14.04.2020)
Get full text
Journal Article