Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila
Ling, Daijun, Song, Ho-Juhn, Garza, Dan, Neufeld, Thomas P, Salvaterra, Paul M
Published in PloS one (15.01.2009)
Published in PloS one (15.01.2009)
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The Toll→NFκB Signaling Pathway Mediates the Neuropathological Effects of the Human Alzheimer's Aβ42 Polypeptide in Drosophila
Tan, Lihua, Schedl, Paul, Song, Ho-Juhn, Garza, Dan, Konsolaki, Mary
Published in PloS one (17.12.2008)
Published in PloS one (17.12.2008)
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Journal Article
G-749, a novel FLT3 kinase inhibitor, can overcome drug resistance for the treatment of acute myeloid leukemia
Lee, Hee Kyu, Kim, Hong Woo, Lee, In Yong, Lee, Jungmi, Lee, Jaekyoo, Jung, Dong Sik, Lee, Sang Yeop, Park, Sung Ho, Hwang, Haejun, Choi, Jang-Sik, Kim, Jung-Ho, Kim, Se Won, Kim, Jung Keun, Cools, Jan, Koh, Jong Sung, Song, Ho-Juhn
Published in Blood (03.04.2014)
Published in Blood (03.04.2014)
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Journal Article
Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Lee, Sang Jae, Choi, Jang‐Sik, Han, Byeong‐Gu, Kim, Hyoun Sook, Song, Ho‐Juhn, Lee, Jaekyoo, Nam, Seungyoon, Goh, Sung‐Ho, Kim, Jung‐Ho, Koh, Jong Sung, Lee, Byung Il
Published in The FEBS journal (01.10.2016)
Published in The FEBS journal (01.10.2016)
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Journal Article
Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode
Lee, Sang Jae, Han, Byeong-Gu, Cho, Jea-Won, Choi, Jang-Sik, Lee, Jaekyoo, Song, Ho-Juhn, Koh, Jong Sung, Lee, Byung Il
Published in PloS one (31.07.2013)
Published in PloS one (31.07.2013)
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Correction: Crystal Structure of Pim1 Kinase in Complex with a Pyrido[4,3-D]Pyrimidine Derivative Suggests a Unique Binding Mode
Lee, Sang Jae, Han, Byeong-Gu, Cho, Jea-Won, Choi, Jang-Sik, Lee, Jaekyoo, Song, Ho-Juhn, Koh, Jong Sung, Lee, Byung Il
Published in PloS one (02.01.2018)
Published in PloS one (02.01.2018)
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Journal Article
Superior Efficacy and Selectivity of Novel Small-Molecule Kinase Inhibitors of T790M-Mutant EGFR in Preclinical Models of Lung Cancer
Rho, Jin Kyung, Lee, In Yong, Choi, Yun Jung, Choi, Chang-Min, Hur, Jae-Young, Koh, Jong Sung, Lee, Jaekyoo, Suh, Byung-Chul, Song, Ho-Juhn, Salgaonkar, Paresh, Lee, Jungmi, Lee, Jaesang, Jung, Dong Sik, Kim, Sang-Yeob, Woo, Dong-Cheol, Baek, In-Jeoung, Lee, Joo-Yong, Ha, Chang Hoon, Sung, Young Hoon, Kim, Jeong Kon, Kim, Woo Sung, Song, Joon Seon, Kim, Cheol Hyeon, Bivona, Trever G, Lee, Jae Cheol
Published in Cancer research (Chicago, Ill.) (01.03.2017)
Published in Cancer research (Chicago, Ill.) (01.03.2017)
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YH25448, an Irreversible EGFR-TKI with Potent Intracranial Activity in EGFR Mutant Non-Small Cell Lung Cancer
Yun, Jiyeon, Hong, Min Hee, Kim, Seok-Young, Park, Chae-Won, Kim, Soyoung, Yun, Mi Ran, Kang, Han Na, Pyo, Kyoung-Ho, Lee, Sung Sook, Koh, Jong Sung, Song, Ho-Juhn, Kim, Dong Kyun, Lee, Young-Sung, Oh, Se-Woong, Choi, Soongyu, Kim, Hye Ryun, Cho, Byoung Chul
Published in Clinical cancer research (15.04.2019)
Published in Clinical cancer research (15.04.2019)
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Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors
Lee, Sang Jae, Choi, Jang-Sik, Bong, Seoung Min, Hwang, Hae-Jun, Lee, Jaesang, Song, Ho-Juhn, Lee, Jaekyoo, Kim, Jung-Ho, Koh, Jong Sung, Lee, Byung Il
Published in Molecules and cells (2018)
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Published in Molecules and cells (2018)
Journal Article
Molecular Genetic Dissection of the Sex-Specific and Vital Functions of the Drosophila melanogaster Sex Determination Gene fruitless
Anand, Anuranjan, Villella, Adriana, Ryner, Lisa C, Carlo, Troy, Goodwin, Stephen F, Song, Ho-Juhn, Gailey, Donald A, Morales, Ana, Hall, Jeffrey C, Baker, Bruce S, Taylor, Barbara J
Published in Genetics (Austin) (01.08.2001)
Published in Genetics (Austin) (01.08.2001)
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A model for studying Alzheimer's Aβ42-induced toxicity in Drosophila melanogaster
Finelli, Alyce, Kelkar, Anju, Song, Ho-Juhn, Yang, Haidi, Konsolaki, Mary
Published in Molecular and cellular neuroscience (01.07.2004)
Published in Molecular and cellular neuroscience (01.07.2004)
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Journal Article
The fruitless Gene Is Required for the Proper Formation of Axonal Tracts in the Embryonic Central Nervous System of Drosophila
Song, Ho-Juhn, Billeter, Jean-Christophe, Reynaud, Enrique, Carlo, Troy, Spana, Eric P, Perrimon, Norbert, Goodwin, Stephen F, Baker, Bruce S, Taylor, Barbara J
Published in Genetics (Austin) (01.12.2002)
Published in Genetics (Austin) (01.12.2002)
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Identification of novel genes that modify phenotypes induced by Alzheimer's β-amyloid overexpression in Drosophila
Cao, W, Song, H.J, Gangi, T, Kelkar, A, Antani, I, Garza, D, Konsolaki, M
Published in Genetics (Austin) (01.03.2008)
Published in Genetics (Austin) (01.03.2008)
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Journal Article
Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors
Choi, Jang-Sik, Hwang, Hae-jun, Kim, Se-Won, Lee, Byung Il, Lee, Jaekyoo, Song, Ho-Juhn, Koh, Jong Sung, Kim, Jung-Ho, Lee, Phil Ho
Published in Bioorganic & medicinal chemistry letters (15.10.2015)
Published in Bioorganic & medicinal chemistry letters (15.10.2015)
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Journal Article
Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors
Lee, Sang Jae, Choi, Jang-Sik, Bong, Seoung Min, Hwang, Hae-Jun, Lee, Jaesang, Song, Ho-Juhn, Lee, Jaekyoo, Kim, Jung-Ho, Koh, Jong Sung, Lee, Byung Il
Published in Molecules and cells (01.06.2018)
Published in Molecules and cells (01.06.2018)
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Journal Article
PYRROLO(PYRAZOLO)PYRIMIDINE DERIVATIVE AS LRRK2 INHIBITOR
KIM, Se-Won, JUNG, Dong-Sik, KIM, Jung-Ho, LEE, Jaesang, KIM, Hwa Sil, SONG, Ho-Juhn, CHOI, Jang-Sik, PARK, Song-Eun, KOH, Jong-Sung, LEE, Jaekyoo
Year of Publication 13.06.2019
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Year of Publication 13.06.2019
Patent
Abstract 2010: SKI-G-801, an AXL kinase inhibitor, blocks metastasis and induces anti-tumor immune responses in various syngeneic cancer models
Xin, Chun-Feng, Kim, Sung Eun, Pyo, Kyoung-Ho, Jo, Ha Ni, Cho, Jae Seok, Kim, Jae Hwan, Lee, Wongeun, Lee, Hee Kyu, Kim, Jung-Ho, Song, Ho-Juhn, Koh, Jong Sung, Cho, Byoung Chul
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 4790: YH25448, an irreversible 3rd generation EGFR TKI, exhibits superior anticancer effects with potent brain BBB penetration in NSCLC
Yun, Jiyeon, Hong, Min Hee, Kim, Seok-Young, Park, Chae Won, Kim, So-Young, Yun, Mi Ran, Kang, Han Na, Pyo, Kyoung-Ho, Koh, Jong Sung, Song, Ho-Juhn, Lee, Young- Sung, Oh, Se-Woong, Choi, Soongyu, Cho, Byoung-Chul
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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