A first‐in‐human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers
Sjöberg, Folke, Waters, Susanna, Löfberg, Boel, Sonesson, Clas, Waters, Nicholas, Tedroff, Joakim
Published in Pharmacology research & perspectives (01.05.2021)
Published in Pharmacology research & perspectives (01.05.2021)
Get full text
Journal Article
Preclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson Disease
Waters, Susanna, Sonesson, Clas, Svensson, Peder, Tedroff, Joakim, Carta, Manolo, Ljung, Elisabeth, Gunnergren, Jenny, Edling, Malin, Svanberg, Boel, Fagerberg, Anne, Kullingsjö, Johan, Hjorth, Stephan, Waters, Nicholas
Published in The Journal of pharmacology and experimental therapeutics (01.07.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2020)
Get full text
Journal Article
Systematic in Vivo Screening of a Series of 1‑Propyl-4-arylpiperidines against Dopaminergic and Serotonergic Properties in Rat Brain: A Scaffold-Jumping Approach
Mattsson, Cecilia, Andreasson, Theresa, Waters, Nicholas, Sonesson, Clas
Published in Journal of medicinal chemistry (26.11.2012)
Published in Journal of medicinal chemistry (26.11.2012)
Get full text
Journal Article
Synthesis and Evaluation of a Set of Para-Substituted 4-Phenylpiperidines and 4-Phenylpiperazines as Monoamine Oxidase (MAO) Inhibitors
Pettersson, Fredrik, Svensson, Peder, Waters, Susanna, Waters, Nicholas, Sonesson, Clas
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
Get full text
Journal Article
2-아민의 제약상 허용되는 염 및 그의 용도
REINE INESE, SONESSON CLAS, TEDROFF JOAKIM MIHKEL, WATERS ROSS NICHOLAS
Year of Publication 28.01.2022
Get full text
Year of Publication 28.01.2022
Patent
Synthesis and Evaluation of a Set of 4-Phenylpiperidines and 4-Phenylpiperazines as D-2 Receptor Ligands and the Discovery of the Dopaminergic Stabilizer 4[3-(Methylsulfonyl)phenyl]-1-propylpiperidine (Huntexil, Pridopidine, ACR16)
Pettersson, Fredrik, Ponten, Henrik, Waters, Nicholas, Waters, Susanna, Sonesson, Clas
Published in Journal of medicinal chemistry (25.03.2010)
Published in Journal of medicinal chemistry (25.03.2010)
Get full text
Journal Article
The dopaminergic stabilizers pridopidine (ACR16) and (−)-OSU6162 display dopamine D 2 receptor antagonism and fast receptor dissociation properties
Dyhring, Tino, Nielsen, Elsebet Ø., Sonesson, Clas, Pettersson, Fredrik, Karlsson, Jonas, Svensson, Peder, Christophersen, Palle, Waters, Nicholas
Published in European journal of pharmacology (25.02.2010)
Published in European journal of pharmacology (25.02.2010)
Get full text
Journal Article
Structure–activity relationship of 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole analogues as 5-HT6 receptor agonists
Mattsson, Cecilia, Svensson, Peder, Boettcher, Henning, Sonesson, Clas
Published in European journal of medicinal chemistry (01.05.2013)
Published in European journal of medicinal chemistry (01.05.2013)
Get full text
Journal Article
Synthesis, pharmacological evaluation and QSAR modeling of mono-substituted 4-phenylpiperidines and 4-phenylpiperazines
Pettersson, Fredrik, Svensson, Peder, Waters, Susanna, Waters, Nicholas, Sonesson, Clas
Published in European journal of medicinal chemistry (01.04.2013)
Published in European journal of medicinal chemistry (01.04.2013)
Get full text
Journal Article
A Phase 2a Trial Investigating the Safety and Tolerability of the Novel Cortical Enhancer IRL752 in Parkinson's Disease Dementia
Svenningsson, Per, Odin, Per, Dizdar, Nil, Johansson, Anders, Grigoriou, Sotirios, Tsitsi, Panagiota, Wictorin, Klas, Bergquist, Filip, Nyholm, Dag, Rinne, Juha, Hansson, Fredrik, Sonesson, Clas, Tedroff, Joakim, Andersson, Kristina, Sundgren, Mathias, Duzynski, Wojciech, Carlström, Christian
Published in Movement disorders (01.06.2020)
Published in Movement disorders (01.06.2020)
Get full text
Journal Article
Correction to Systematic in Vivo Screening of a Series of 1‑Propyl-4-arylpiperidines against Dopaminergic and Serotonergic Properties in Rat Brain: A Scaffold-Jumping Approach
Mattsson, Cecilia, Andreasson, Theresa, Waters, Nicholas, Sonesson, Clas
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
Get full text
Journal Article
The dopaminergic stabilizers pridopidine (ACR16) and (―)-OSU6162 display dopamine D2 receptor antagonism and fast receptor dissociation properties
DYHRING, Tino, NIELSEN, Elsebet O, SONESSON, Clas, PETTERSSON, Fredrik, KARLSSON, Jonas, SVENSSON, Peder, CHRISTOPHERSEN, Palle, WATERS, Nicholas
Published in European journal of pharmacology (25.02.2010)
Published in European journal of pharmacology (25.02.2010)
Get full text
Journal Article
2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists
Mattsson, Cecilia, Sonesson, Clas, Sandahl, Anna, Greiner, Hartmut E., Gassen, Michael, Plaschke, Jörg, Leibrock, Joachim, Böttcher, Henning
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
Get full text
Journal Article
First‐in‐Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Pirepemat, a Cortical Enhancer, in Healthy Volunteers
Rein‐Hedin, Erik, Sjöberg, Folke, Waters, Susanna, Sonesson, Clas, Waters, Nicholas, Huss, Fredrik, Tedroff, Joakim
Published in Clinical pharmacology in drug development (01.12.2021)
Published in Clinical pharmacology in drug development (01.12.2021)
Get full text
Journal Article
Potential anxiolytic properties of R-(+)-8-OSO2CF3-PAT, a 5-HT1A receptor agonist
BARF, T, KORTE, S. M, KORTE-BOWS, G, SONESSON, C, DAMSMA, G, BOHUS, B, WIKSTRÖM, H
Published in European journal of pharmacology (22.02.1996)
Published in European journal of pharmacology (22.02.1996)
Get full text
Journal Article