2‑(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as Potent Transient Receptor Potential Vanilloid 1 (TRPV1) Antagonists: Structure–Activity Relationships of 2‑Amino Derivatives in the N‑(6-Trifluoromethylpyridin-3-ylmethyl) C‑Region
Kim, Myeong Seop, Ryu, HyungChul, Kang, Dong Wook, Cho, Seong-Hee, Seo, Sejin, Park, Young Soo, Kim, Mi-Yeon, Kwak, Eun Joo, Kim, Yong Soo, Bhondwe, Rahul S, Kim, Ho Shin, Park, Seul-gi, Son, Karam, Choi, Sun, DeAndrea-Lazarus, Ian A, Pearce, Larry V, Blumberg, Peter M, Frank, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Kögel, Babette Y, Schiene, Klaus, Christoph, Thomas, Lee, Jeewoo
Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
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Promiscuous gating modifiers target the voltage sensor of K(v)7.2, TRPV1, and H(v)1 cation channels
Kornilov, Polina, Peretz, Asher, Lee, Yoonji, Son, Karam, Lee, Jin Hee, Refaeli, Bosmat, Roz, Netta, Rehavi, Moshe, Choi, Sun, Attali, Bernard
Published in The FASEB journal (01.06.2014)
Published in The FASEB journal (01.06.2014)
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2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists: Structure activity relationships of the 2-oxy pyridine C-region
Thorat, Shivaji A., Kang, Dong Wook, Ryu, HyungChul, Kim, Myeong Seop, Kim, Ho Shin, Ann, Jihyae, Ha, Taehwan, Kim, Sung-Eun, Son, Karam, Choi, Sun, Blumberg, Peter M., Frank, Robert, Bahrenberg, Gregor, Schiene, Klaus, Christoph, Thomas, Lee, Jeewoo
Published in European journal of medicinal chemistry (01.06.2013)
Published in European journal of medicinal chemistry (01.06.2013)
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TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides
Ha, Tae-Hwan, Ryu, HyungChul, Kim, Sung-Eun, Kim, Ho Shin, Ann, Jihyae, Tran, Phuong-Thao, Hoang, Van-Hai, Son, Karam, Cui, Minghua, Choi, Sun, Blumberg, Peter M., Frank, Robert, Bahrenberg, Gregor, Schiene, Klaus, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry (01.11.2013)
Published in Bioorganic & medicinal chemistry (01.11.2013)
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2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists
Ryu, HyungChul, Seo, Sejin, Cho, Seong-Hee, Kim, Ho Shin, Jung, Aeran, Kang, Dong Wook, Son, Karam, Cui, Minghua, Hong, Sun-hye, Sharma, Pankaz Kumar, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Stockhausen, Hannelore, Schiene, Klaus, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
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2-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists
Ryu, HyungChul, Seo, Sejin, Kim, Myeong Seop, Kim, Mi-Yeon, Kim, Ho Shin, Ann, Jihyae, Tran, Phuong-Thao, Hoang, Van-Hai, Byun, Jieun, Cui, Minghua, Son, Karam, Sharma, Pankaz Kumar, Choi, Sun, Blumberg, Peter M., Frank-Foltyn, Robert, Bahrenberg, Gregor, Koegel, Babette-Yvonne, Christoph, Thomas, Frormann, Sven, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
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Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands
Kim, Myeong Seop, Ki, Yooran, Ahn, Song Yeon, Yoon, Suyoung, Kim, Sung-Eun, Park, Hyeung-Geun, Sun, Wei, Son, Karam, Cui, Minghua, Choi, Sun, Pearce, Larry V., Esch, Timothy E., DeAndrea-Lazarus, Ian A., Blumberg, Peter M., Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
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The carbonate analogues of 5′-halogenated resiniferatoxin as TRPV1 ligands
Lim, Kwang Su, Lee, Hobin, Kim, Sung Eun, Ha, Tae-Hwan, Ann, Jihyae, Son, Karam, Choi, Sun, Sun, Wei, Pearce, Larry V., DeAndrea-Lazarus, Ian A., Blumberg, Peter M., Lee, Jeewoo
Published in European journal of medicinal chemistry (01.10.2013)
Published in European journal of medicinal chemistry (01.10.2013)
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Structure-activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-Na2-[4-(methylsulfonylamino)benzy l] thiourea template for TRPV1 antagonism
Bhondwe, Rahul S, Kang, Dong Wook, Kim, Myeong Seop, Kim, Ho Shin, Park, Seul-gi, Son, Karam, Choi, Sun, Lang Kuhs, Krystle A, Pavlyukovets, Vladimir A, Pearce, Larry V, Blumberg, Peter M, Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (01.06.2012)
Published in Bioorganic & medicinal chemistry letters (01.06.2012)
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Journal Article
Structure–activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-N′-[4-(methylsulfonylamino)benzyl] thiourea template for TRPV1 antagonism
Bhondwe, Rahul S., Kang, Dong Wook, Kim, Myeong Seop, Kim, Ho Shin, Park, Seul-gi, Son, Karam, Choi, Sun, Lang Kuhs, Krystle A., Pavlyukovets, Vladimir A., Pearce, Larry V., Blumberg, Peter M., Lee, Jeewoo
Published in Bioorganic & medicinal chemistry letters (01.06.2012)
Published in Bioorganic & medicinal chemistry letters (01.06.2012)
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