AGI-1067: A Multifunctional Phenolic Antioxidant, Lipid Modulator, Anti-Inflammatory and Antiatherosclerotic Agent
Sundell, Cynthia L, Somers, Patricia K, Meng, Charles Q, Hoong, Lee K, Suen, Ki-Ling, Hill, Russell R, Landers, Laura K, Chapman, Angela, Butteiger, Dustie, Jones, Moira, Edwards, David, Daugherty, Alan, Wasserman, Martin A, Alexander, R Wayne, Medford, Russell M, Saxena, Uday
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
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Discovery of Novel Phenolic Antioxidants as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases
Meng, Charles Q, Somers, Patricia K, Hoong, Lee K, Zheng, X. Sharon, Ye, Zhihong, Worsencroft, Kimberly J, Simpson, Jacob E, Hotema, Martha R, Weingarten, M. David, MacDonald, Mathew L, Hill, Russell R, Marino, Elaine M, Suen, Ki-Ling, Luchoomun, Jayraz, Kunsch, Charles, Landers, Laura K, Stefanopoulos, Dimitria, Howard, Randy B, Sundell, Cynthia L, Saxena, Uday, Wasserman, Martin A, Sikorski, James A
Published in Journal of medicinal chemistry (02.12.2004)
Published in Journal of medicinal chemistry (02.12.2004)
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Dithiocarbamates: effects on lipid hydroperoxides and vascular inflammatory gene expression
Somers, Patricia K, Medford, Russell M, Saxena, Uday
Published in Free radical biology & medicine (15.05.2000)
Published in Free radical biology & medicine (15.05.2000)
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Journal Article
Total synthesis of the immunosuppressive agent (-)-discodermolide
Nerenberg, Jennie B, Hung, Deborah T, Somers, Patricia K, Schreiber, Stuart L
Published in Journal of the American Chemical Society (01.12.1993)
Published in Journal of the American Chemical Society (01.12.1993)
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AGIX-4207 [2-[4-[[1-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic Acid], a Novel Antioxidant and Anti-Inflammatory Compound: Cellular and Biochemical Characterization of Antioxidant Activity and Inhibition of Redox-Sensitive Inflammatory Gene Expression
Kunsch, Charles, Luchoomun, Jayraz, Chen, Xi-Lin, Dodd, Geraldine L, Karu, Kanika S, Meng, Charles Q, Marino, Elaine M, Olliff, Lyn K, Piper, J Daniel, Qiu, Fei-Hua, Sikorski, James A, Somers, Patricia K, Suen, Ki-Ling, Thomas, Suzanne, Whalen, Anne M, Wasserman, Martin A, Sundell, Cynthia L
Published in The Journal of pharmacology and experimental therapeutics (01.05.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2005)
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Journal Article
Synthesis and analysis of 506BD, a high-affinity ligand for the immunophilin FKBP
Somers, Patricia K, Wandless, Thomas J, Schreiber, Stuart L
Published in Journal of the American Chemical Society (01.10.1991)
Published in Journal of the American Chemical Society (01.10.1991)
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Lead discovery of α,β-Unsaturated sulfones from a combinatorial library as inhibitors of inducible VCAM-1 expression
Ni, Liming, Zheng, X.Sharon, Somers, Patricia K., Hoong, Lee K., Hill, Russell R., Marino, Elaine M., Suen, Ki-Ling, Saxena, Uday, Meng, Charles Q.
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
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Journal Article
Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis
Meng, Charles Q., Somers, Patricia K., Rachita, Carolyn L., Holt, Lisa A., Hoong, Lee K., Zheng, X.Sharon, Simpson, Jacob E., Hill, Russell R., Olliff, Lynda K., Kunsch, Charles, Sundell, Cynthia L., Parthasarathy, Sampath, Saxena, Uday, Sikorski, James A., Wasserman, Martin A.
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
Published in Bioorganic & medicinal chemistry letters (16.09.2002)
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Journal Article
Total Synthesis of Brevetoxin A: Part 1: First Generation Strategy and Construction of BCD Ring System
Nicolaou, K. C., Bunnage, Mark E., McGarry, Daniel G., Shi, Shuhao, Somers, Patricia K., Wallace, Paul A., Chu, Xin-Jie, Agrios, Konstantinos A., Gunzner, Janet L., Yang, Zhen
Published in Chemistry : a European journal (01.02.1999)
Published in Chemistry : a European journal (01.02.1999)
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Journal Article
Effects of AGI-1096, a novel antioxidant compound with anti-inflammatory and antiproliferative properties, on rodent allograft arteriosclerosis
Murata, Seiichiro, Sundell, Cynthia L, Lijkwan, Maarten A, Balsam, Leora B, Hammainen, Pekka, Coleman, Caroline, York, Chris, Luchoomun, Jayraz, Suen, Ki-Ling, Howard, Randy, Somers, Patricia K, Morris, Randall E, Robbins, Robert C
Published in Transplantation (27.05.2004)
Published in Transplantation (27.05.2004)
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Nitrobenzene compounds inhibit expression of VCAM-1
MENG, Charles Q, ZHENG, X. Sharon, HOLT, Lisa A, HOONG, Lee K, SOMERS, Patricia K, HILL, Russell R, SAXENA, Uday
Published in Bioorganic & medicinal chemistry letters (23.07.2001)
Published in Bioorganic & medicinal chemistry letters (23.07.2001)
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