Loading…
Loading…
Diversification of the VH3‐53 immunoglobulin gene segment by somatic hypermutation results in neutralization of SARS‐CoV‐2 virus variants
Bruhn, Matthias, Obara, Maureen, Salam, Abdus, Costa, Bibiana, Ziegler, Annett, Waltl, Inken, Pavlou, Andreas, Hoffmann, Markus, Graalmann, Theresa, Pöhlmann, Stefan, Schambach, Axel, Kalinke, Ulrich
Published in European journal of immunology (01.07.2024)
Published in European journal of immunology (01.07.2024)
Get full text
Journal Article
Loading…
Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation
Beltrán, Eduardo, Obermeier, Birgit, Moser, Markus, Coret, Francisco, Simó-Castelló, María, Boscá, Isabel, Pérez-Miralles, Francisco, Villar, Luisa M., Senel, Makbule, Tumani, Hayrettin, Hohlfeld, Reinhard, Casanova, Bonaventura, Dornmair, Klaus
Published in Brain (London, England : 1878) (01.10.2014)
Published in Brain (London, England : 1878) (01.10.2014)
Get full text
Journal Article
Loading…
Sex-Biased Aging Effects on Ig Somatic Hypermutation Targeting
Cui, Ang, Chawla, Daniel G, Kleinstein, Steven H
Published in The Journal of immunology (1950) (01.01.2021)
Published in The Journal of immunology (1950) (01.01.2021)
Get full text
Journal Article
Loading…
Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint
Cantaert, Tineke, Schickel, Jean-Nicolas, Bannock, Jason M., Ng, Yen-Shing, Massad, Christopher, Delmotte, Fabien R., Yamakawa, Natsuko, Glauzy, Salome, Chamberlain, Nicolas, Kinnunen, Tuure, Menard, Laurence, Lavoie, Aubert, Walter, Jolan E., Notarangelo, Luigi D., Bruneau, Julie, Al-Herz, Waleed, Kilic, Sara Sebnem, Ochs, Hans D., Cunningham-Rundles, Charlotte, van der Burg, Mirjam, Kuijpers, Taco W., Kracker, Sven, Kaneko, Hideo, Sekinaka, Yujin, Nonoyama, Shigeaki, Durandy, Anne, Meffre, Eric
Published in The Journal of clinical investigation (01.11.2016)
Published in The Journal of clinical investigation (01.11.2016)
Get full text
Journal Article
Loading…
Sex-biased aging effects on immunoglobulin somatic hypermutation targeting
Cui, Ang, Chawla, Daniel G., Kleinstein, Steven H.
Published in The Journal of immunology (1950) (07.12.2020)
Published in The Journal of immunology (1950) (07.12.2020)
Get full text
Journal Article
Loading…
Targeting Of Somatic Hypermutation By immunoglobulin Enhancer And Enhancer-Like Sequences
Buerstedde, Jean-Marie, Alinikula, Jukka, Arakawa, Hiroshi, McDonald, Jessica J., Schatz, David G.
Published in PLoS biology (01.04.2014)
Published in PLoS biology (01.04.2014)
Get full text
Journal Article
Loading…
Polyreactivity and Somatic Hypermutation Analysis Reveals the Innate B Cell Origin of Human PF4/Heparin Reactive Antibodies
Zhu, Wen, Zhou, Lu, Zhao, Ting, Zheng, Yongwei, Yu, Mei, Wei, Jianhui, Padmanabhan, Anand, Aster, Richard H., Wang, Demin, Wen, Renren
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
Get full text
Journal Article
Loading…
Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting
Longo, Nancy S., Lugar, Patricia L., Yavuz, Sule, Zhang, Wen, Krijger, Peter H.L., Russ, Daniel E., Jima, Dereje D., Dave, Sandeep S., Grammer, Amrie C., Lipsky, Peter E.
Published in Blood (16.04.2009)
Published in Blood (16.04.2009)
Get full text
Journal Article
Loading…
Loading…
Loading…
De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease
Mattoo, Hamid, Mahajan, Vinay S., Della-Torre, Emanuel, Sekigami, Yurie, Carruthers, Mollie, Wallace, Zachary S., Deshpande, Vikram, Stone, John H., Pillai, Shiv
Published in Journal of allergy and clinical immunology (01.09.2014)
Published in Journal of allergy and clinical immunology (01.09.2014)
Get full text
Journal Article
Loading…
Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production
Chen, Yuezhou, Zuiani, Adam, Fischinger, Stephanie, Mullur, Jyotsna, Atyeo, Caroline, Travers, Meghan, Lelis, Felipe J.N., Pullen, Krista M., Martin, Hannah, Tong, Pei, Gautam, Avneesh, Habibi, Shaghayegh, Bensko, Jillian, Gakpo, Deborah, Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Cai, Yongfei, Burke, John S., Lin, Junrui, Lederer, James A., Lam, Evan Christopher, Lavine, Christy L., Seaman, Michael S., Chen, Bing, Schmidt, Aaron G., Balazs, Alejandro Benjamin, Lauffenburger, Douglas A., Alter, Galit, Wesemann, Duane R.
Published in Cell (10.12.2020)
Published in Cell (10.12.2020)
Get full text
Journal Article
Loading…
Commonality despite exceptional diversity in the baseline human antibody repertoire
Briney, Bryan, Inderbitzin, Anne, Joyce, Collin, Burton, Dennis R.
Published in Nature (London) (01.02.2019)
Published in Nature (London) (01.02.2019)
Get full text
Journal Article
Loading…
Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation
Seydoux, Emilie, Homad, Leah J., MacCamy, Anna J., Parks, K. Rachael, Hurlburt, Nicholas K., Jennewein, Madeleine F., Akins, Nicholas R., Stuart, Andrew B., Wan, Yu-Hsin, Feng, Junli, Whaley, Rachael E., Singh, Suruchi, Boeckh, Michael, Cohen, Kristen W., McElrath, M. Juliana, Englund, Janet A., Chu, Helen Y., Pancera, Marie, McGuire, Andrew T., Stamatatos, Leonidas
Published in Immunity (Cambridge, Mass.) (14.07.2020)
Published in Immunity (Cambridge, Mass.) (14.07.2020)
Get full text
Journal Article
Loading…
Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data
Gadala-Maria, Daniel, Gidoni, Moriah, Marquez, Susanna, Vander Heiden, Jason A., Kos, Justin T., Watson, Corey T., O'Connor, Kevin C., Yaari, Gur, Kleinstein, Steven H.
Published in Frontiers in immunology (13.02.2019)
Published in Frontiers in immunology (13.02.2019)
Get full text
Journal Article
Loading…
Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes
Li, Q.-Z, Zhou, J, Lian, Y, Zhang, B, Branch, V.K, Carr-Johnson, F, Karp, D.R, Mohan, C, Wakeland, E.K, Olsen, N.J
Published in Clinical and experimental immunology (01.03.2010)
Published in Clinical and experimental immunology (01.03.2010)
Get full text
Journal Article
Loading…
Antibody lineages with evidence of somatic hypermutation persisting for >4 years in a South African subject with broad neutralizing activity
Moody, M, Trama, AM, Bonsignori, M, Tsao, C, Drinker, MS, Gurley, TC, Amos, JD, Eudailey, JA, Armand, LC, Parks, R, Lloyd, KE, Wang, S, Seo, K, Lee, J, Jackson, KJ, Hoh, R, Pham, T, Roskin, KM, Boyd, SD, Fire, AZ, Gray, ES, Morris, L, Liao, H, Tomaras, GD, Kepler, TB, Kelsoe, G, Haynes, BF
Published in Retrovirology (13.09.2012)
Published in Retrovirology (13.09.2012)
Get full text
Journal Article
Loading…
Human B-cell isotype switching origins of IgE
Looney, Timothy J., Lee, Ji-Yeun, Roskin, Krishna M., Hoh, Ramona A., King, Jasmine, Glanville, Jacob, Liu, Yi, Pham, Tho D., Dekker, Cornelia L., Davis, Mark M., Boyd, Scott D.
Published in Journal of allergy and clinical immunology (01.02.2016)
Published in Journal of allergy and clinical immunology (01.02.2016)
Get full text
Journal Article
Loading…
Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination
Hoehn, Kenneth B., Vander Heiden, Jason A., Zhou, Julian Q., Lunter, Gerton, Pybus, Oliver G., Kleinstein, Steven H.
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
Get full text
Journal Article