Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events
Sabatine, Marc S, Giugliano, Robert P, Wiviott, Stephen D, Raal, Frederick J, Blom, Dirk J, Robinson, Jennifer, Ballantyne, Christie M, Somaratne, Ransi, Legg, Jason, Wasserman, Scott M, Scott, Robert, Koren, Michael J, Stein, Evan A
Published in The New England journal of medicine (16.04.2015)
Published in The New England journal of medicine (16.04.2015)
Get full text
Journal Article
Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial
Hirschfield, Gideon M., Chazouillères, Olivier, Drenth, Joost P., Thorburn, Douglas, Harrison, Stephen A., Landis, Charles S., Mayo, Marlyn J., Muir, Andrew J., Trotter, James F., Leeming, Diana J., Karsdal, Morten A., Jaros, Mark J., Ling, Lei, Kim, Kathline H., Rossi, Stephen J., Somaratne, Ransi M., DePaoli, Alex M., Beuers, Ulrich
Published in Journal of hepatology (01.03.2019)
Published in Journal of hepatology (01.03.2019)
Get full text
Journal Article
PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial
Raal, Frederick J, Prof, Stein, Evan A, Prof, Dufour, Robert, MD, Turner, Traci, MD, Civeira, Fernando, MD, Burgess, Lesley, Prof, Langslet, Gisle, MD, Scott, Russell, Prof, Olsson, Anders G, Prof, Sullivan, David, MD, Hovingh, G Kees, MD, Cariou, Bertrand, MD, Gouni-Berthold, Ioanna, MD, Somaratne, Ransi, MD, Bridges, Ian, MSc, Scott, Rob, MD, Wasserman, Scott M, MD, Gaudet, Daniel, Prof
Published in The Lancet (British edition) (24.01.2015)
Published in The Lancet (British edition) (24.01.2015)
Get full text
Journal Article
Effect of Evolocumab on Coronary Plaque Composition
Nicholls, Stephen J., Puri, Rishi, Anderson, Todd, Ballantyne, Christie M., Cho, Leslie, Kastelein, John J.P., Koenig, Wolfgang, Somaratne, Ransi, Kassahun, Helina, Yang, Jingyuan, Wasserman, Scott M., Honda, Satoshi, Shishikura, Daisuke, Scherer, Daniel J., Borgman, Marilyn, Brennan, Danielle M., Wolski, Kathy, Nissen, Steven E.
Published in Journal of the American College of Cardiology (23.10.2018)
Published in Journal of the American College of Cardiology (23.10.2018)
Get full text
Journal Article
PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role[S]
Raal, Frederick J., Giugliano, Robert P., Sabatine, Marc S., Koren, Michael J., Blom, Dirk, Seidah, Nabil G., Honarpour, Narimon, Lira, Armando, Xue, Allen, Chiruvolu, Padmaja, Jackson, Simon, Di, Mei, Peach, Matthew, Somaratne, Ransi, Wasserman, Scott M., Scott, Rob, Stein, Evan A.
Published in Journal of lipid research (01.06.2016)
Published in Journal of lipid research (01.06.2016)
Get full text
Journal Article
Factorial Effects of Evolocumab and Atorvastatin on Lipoprotein Metabolism
Watts, Gerald F, Chan, Dick C, Dent, Ricardo, Somaratne, Ransi, Wasserman, Scott M, Scott, Rob, Burrows, Sally, R. Barrett, P Hugh
Published in Circulation (New York, N.Y.) (24.01.2017)
Published in Circulation (New York, N.Y.) (24.01.2017)
Get full text
Journal Article
Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): a randomised, placebo-controlled, dose-ranging, phase 2 study
Giugliano, Robert P, Dr, Desai, Nihar R, MD, Kohli, Payal, MD, Rogers, William J, Prof, Somaratne, Ransi, MD, Huang, Fannie, MS, Liu, Thomas, PhD, Mohanavelu, Satishkumar, MS, Hoffman, Elaine B, PhD, McDonald, Shannon T, BSN, Abrahamsen, Timothy E, BA, Wasserman, Scott M, MD, Scott, Robert, MD, Sabatine, Marc S, MD
Published in The Lancet (British edition) (08.12.2012)
Published in The Lancet (British edition) (08.12.2012)
Get full text
Journal Article
Pooled Safety Analysis of Evolocumab in Over 6000 Patients From Double-Blind and Open-Label Extension Studies
Toth, Peter P, Descamps, Olivier, Genest, Jacques, Sattar, Naveed, Preiss, David, Dent, Ricardo, Djedjos, Constantine, Wu, Yuna, Geller, Michelle, Uhart, Magdalena, Somaratne, Ransi, Wasserman, Scott M
Published in Circulation (New York, N.Y.) (09.05.2017)
Published in Circulation (New York, N.Y.) (09.05.2017)
Get full text
Journal Article
Relationship Between Low-Density Lipoprotein Cholesterol and Lipoprotein(a) Lowering in Response to PCSK9 Inhibition With Evolocumab
Shapiro, Michael D, Minnier, Jessica, Tavori, Hagai, Kassahun, Helina, Flower, Andrea, Somaratne, Ransi, Fazio, Sergio
Published in Journal of the American Heart Association (19.02.2019)
Published in Journal of the American Heart Association (19.02.2019)
Get full text
Journal Article
Lipid-lowering efficacy of the PCSK9 inhibitor evolocumab (AMG 145) in patients with type 2 diabetes: a meta-analysis of individual patient data
Sattar, Naveed, Prof, Preiss, David, PhD, Robinson, Jennifer G, MD, Djedjos, C Stephen, MD, Elliott, Mary, MSc, Somaratne, Ransi, MD, Wasserman, Scott M, MD, Raal, Frederick J, PhD
Published in The lancet. Diabetes & endocrinology (01.05.2016)
Published in The lancet. Diabetes & endocrinology (01.05.2016)
Get full text
Journal Article
Effect of Evolocumab on Lipoprotein Particles
Toth, Peter P., Sattar, Naveed, Blom, Dirk J., Martin, Seth S., Jones, Steven R., Monsalvo, Maria Laura, Elliott, Mary, Davis, Mike, Somaratne, Ransi, Preiss, David
Published in The American journal of cardiology (01.02.2018)
Published in The American journal of cardiology (01.02.2018)
Get full text
Journal Article
AMG 145, a Monoclonal Antibody Against PCSK9, Facilitates Achievement of National Cholesterol Education Program–Adult Treatment Panel III Low-Density Lipoprotein Cholesterol Goals Among High-Risk Patients
Desai, Nihar R., MD, MPH, Giugliano, Robert P., MD, SM, Zhou, Jing, MS, Kohli, Payal, MD, Somaratne, Ransi, MD, Hoffman, Elaine, PhD, Liu, Thomas, PhD, Scott, Robert, MD, Wasserman, Scott M., MD, Sabatine, Marc S., MD, MPH
Published in Journal of the American College of Cardiology (11.02.2014)
Published in Journal of the American College of Cardiology (11.02.2014)
Get full text
Journal Article
Effect of evolocumab on cholesterol synthesis and absorption[S]
Peach, Matthew, Xu, Ren, Fitzpatrick, Dan, Hamilton, Lisa, Somaratne, Ransi, Scott, Robert, Wasserman, Scott M., Djedjos, C. Stephen
Published in Journal of lipid research (01.12.2016)
Published in Journal of lipid research (01.12.2016)
Get full text
Journal Article
Residual risk for coronary heart disease events and mortality despite intensive medical management after myocardial infarction
Brown, Todd M., Bittner, Vera, Colantonio, Lisandro D., Deng, Luqin, Farkouh, Michael E., Limdi, Nita, Monda, Keri L., Rosenson, Robert S., Serban, Maria-Corina, Somaratne, Ransi M., Zhao, Hong, Woodward, Mark, Muntner, Paul
Published in Journal of clinical lipidology (01.03.2020)
Published in Journal of clinical lipidology (01.03.2020)
Get full text
Journal Article
C-reactive protein levels and plaque regression with evolocumab: Insights from GLAGOV
Nelson, Adam J., Puri, Rishi, Brennan, Danielle M., Anderson, Todd J., Cho, Leslie, Ballantyne, Christie M., Kastelein, John JP, Koenig, Wolfgang, Kassahun, Helina, Somaratne, Ransi M., Wasserman, Scott M., Nissen, Steven E., Nicholls, Stephen J.
Published in American journal of preventive cardiology (01.09.2020)
Published in American journal of preventive cardiology (01.09.2020)
Get full text
Journal Article
Erratum to “C-Reactive Protein Levels and Plaque Regression with Evolocumab: Insights From GLAGOV” [American Journal of Preventive Cardiology 3C (2020) 100091]
Nelson, Adam J., Puri, Rishi, Brennan, Danielle M., Anderson, Todd J., Cho, Leslie, Ballantyne, Christie M., Kastelein, John JP, Koenig, Wolfgang, Kassahun, Helina, Somaratne, Ransi M., Wasserman, Scott M., Nissen, Steven E., Nicholls, Stephen J.
Published in American journal of preventive cardiology (01.06.2021)
Published in American journal of preventive cardiology (01.06.2021)
Get full text
Journal Article
A Comparison of Ezetimibe and Evolocumab for Atherogenic Lipid Reduction in Four Patient Populations: A Pooled Efficacy and Safety Analysis of Three Phase 3 Studies
Koren, Michael J., Jones, Peter H., Robinson, Jennifer G., Sullivan, David, Cho, Leslie, Hucko, Thomas, Lopez, J. Antonio G., Fleishman, Alex N., Somaratne, Ransi, Stroes, Erik
Published in Cardiology and Therapy (01.12.2020)
Published in Cardiology and Therapy (01.12.2020)
Get full text
Journal Article
Efficacy and Safety of AMG 145, a Fully Human Monoclonal Antibody to PCSK9: Data from Four Phase 2 Studies in Over 1200 Patients
Raal, Frederick, MD, MMED, PhD, Giugliano, Robert, MD, SM, Koren, Michael J., MD, Sullivan, David, MD, Roth, Eli, MD, Weiss, Robert, MD, Kim, Jae B., MD, Somaratne, Ransi, MD, Yang, Jingyuan, PhD, Liu, Thomas, PhD, Albizem, Moetaz, MD, Scott, Rob, MD, Wasserman, Scott M., MD, Sabatine, Marc, MD, MPH, Stein, Evan, MD, PhD
Published in Journal of clinical lipidology (01.05.2013)
Published in Journal of clinical lipidology (01.05.2013)
Get full text
Journal Article