Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
Flaveny, Colin A., Griffett, Kristine, El-Gendy, Bahaa El-Dien M., Kazantzis, Melissa, Sengupta, Monideepa, Amelio, Antonio L., Chatterjee, Arindam, Walker, John, Solt, Laura A., Kamenecka, Theodore M., Burris, Thomas P.
Published in Cancer cell (13.07.2015)
Published in Cancer cell (13.07.2015)
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A molecular switch regulating transcriptional repression and activation of PPARγ
Shang, Jinsai, Mosure, Sarah A., Zheng, Jie, Brust, Richard, Bass, Jared, Nichols, Ashley, Solt, Laura A., Griffin, Patrick R., Kojetin, Douglas J.
Published in Nature communications (19.02.2020)
Published in Nature communications (19.02.2020)
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Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1
de Vera, Ian Mitchelle S, Giri, Pankaj K, Munoz-Tello, Paola, Brust, Richard, Fuhrmann, Jakob, Matta-Camacho, Edna, Shang, Jinsai, Campbell, Sean, Wilson, Henry D, Granados, Juan, Gardner, William J, Creamer, Trevor P, Solt, Laura. A, Kojetin, Douglas J
Published in ACS chemical biology (15.07.2016)
Published in ACS chemical biology (15.07.2016)
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Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders
Wang, Ran, Campbell, Sean, Amir, Mohammed, Mosure, Sarah A., Bassette, Molly A., Eliason, Amber, Sundrud, Mark S., Kamenecka, Theodore M., Solt, Laura A.
Published in Nature communications (04.01.2021)
Published in Nature communications (04.01.2021)
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Editorial: Immunometabolism of T cells in skin infection, autoimmunity and cancer biology
Peng, Lu, Chen, Ling, Solt, Laura A, Dominical, Venina Marcela, Shen, Zhu
Published in Frontiers in immunology (30.06.2023)
Published in Frontiers in immunology (30.06.2023)
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Perfect timing: circadian rhythms, sleep, and immunity - an NIH workshop summary
Haspel, Jeffrey A, Anafi, Ron, Brown, Marishka K, Cermakian, Nicolas, Depner, Christopher, Desplats, Paula, Gelman, Andrew E, Haack, Monika, Jelic, Sanja, Kim, Brian S, Laposky, Aaron D, Lee, Yvonne C, Mongodin, Emmanuel, Prather, Aric A, Prendergast, Brian J, Reardon, Colin, Shaw, Albert C, Sengupta, Shaon, Szentirmai, Éva, Thakkar, Mahesh, Walker, Wendy E, Solt, Laura A
Published in JCI insight (16.01.2020)
Published in JCI insight (16.01.2020)
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Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle
Amador, Ariadna, Campbell, Sean, Kazantzis, Melissa, Lan, Gary, Burris, Thomas P, Solt, Laura A
Published in PloS one (03.05.2018)
Published in PloS one (03.05.2018)
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Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating SOCS3-dependent inflammation
Sun, Ye, Liu, Chi-Hsiu, SanGiovanni, John Paul, Evans, Lucy P., Tian, Katherine T., Zhang, Bing, Stahl, Andreas, Pu, William T., Kamenecka, Theodore M., Solt, Laura A., Chen, Jing
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (18.08.2015)
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The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis
Solt, Laura A, Kojetin, Douglas J, Burris, Thomas P
Published in Future medicinal chemistry (01.04.2011)
Published in Future medicinal chemistry (01.04.2011)
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Regulation of p53 stability and apoptosis by a ROR agonist
Wang, Yongjun, Solt, Laura A, Kojetin, Douglas J, Burris, Thomas P
Published in PloS one (11.04.2012)
Published in PloS one (11.04.2012)
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Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation
Zhao, Jing, Zhang, Lei, Mu, Xiaodong, Doebelin, Christelle, Nguyen, William, Wallace, Callen, Reay, Daniel P, McGowan, Sara J, Corbo, Lana, Clemens, Paula R, Wilson, Gabriela Mustata, Watkins, Simon C, Solt, Laura A, Cameron, Michael D, Huard, Johnny, Niedernhofer, Laura J, Kamenecka, Theodore M, Robbins, Paul D
Published in PLoS biology (01.06.2018)
Published in PLoS biology (01.06.2018)
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Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity
Hanson, Eric P., MD, Monaco-Shawver, Linda, BA, Solt, Laura A., BS, Madge, Lisa A., PhD, Banerjee, Pinaki P., PhD, May, Michael J., PhD, Orange, Jordan S., MD, PhD
Published in Journal of allergy and clinical immunology (2008)
Published in Journal of allergy and clinical immunology (2008)
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REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2
Huang, Shuo, Liu, Chi-Hsiu, Wang, Zhongxiao, Fu, Zhongjie, Britton, William R., Blomfield, Alexandra K., Kamenecka, Theodore M., Dunaief, Joshua L., Solt, Laura A., Chen, Jing
Published in Redox biology (01.05.2022)
Published in Redox biology (01.05.2022)
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Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells
Wang, Qianli, Robinette, Michelle L, Billon, Cyrielle, Collins, Patrick L, Bando, Jennifer K, Fachi, José Luís, Sécca, Cristiane, Porter, Sofia I, Saini, Ankita, Gilfillan, Susan, Solt, Laura A, Musiek, Erik S, Oltz, Eugene M, Burris, Thomas P, Colonna, Marco
Published in Science immunology (04.10.2019)
Published in Science immunology (04.10.2019)
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Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation
Amador, Ariadna, Huitron-Resendiz, Salvador, Roberts, Amanda J, Kamenecka, Theodore M, Solt, Laura A, Burris, Thomas P
Published in PloS one (07.09.2016)
Published in PloS one (07.09.2016)
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Regulation of Adipogenesis by Natural and Synthetic REV-ERB Ligands
Kumar, Naresh, Solt, Laura A, Wang, Yongjun, Rogers, Pamela M, Bhattacharyya, Gargi, Kamenecka, Theodore M, Stayrook, Keith R, Crumbley, Christine, Floyd, Z. Elizabeth, Gimble, Jeffrey M, Griffin, Patrick R, Burris, Thomas P
Published in Endocrinology (Philadelphia) (01.07.2010)
Published in Endocrinology (Philadelphia) (01.07.2010)
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