Pathogenicity of Influenza Viruses with Genes from the 1918 Pandemic Virus: Functional Roles of Alveolar Macrophages and Neutrophils in Limiting Virus Replication and Mortality in Mice
Tumpey, Terrence M, García-Sastre, Adolfo, Taubenberger, Jeffery K, Palese, Peter, Swayne, David E, Pantin-Jackwood, Mary J, Schultz-Cherry, Stacey, Solórzano, Alicia, Van Rooijen, Nico, Katz, Jacqueline M, Basler, Christopher F
Published in Journal of Virology (01.12.2005)
Published in Journal of Virology (01.12.2005)
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Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
Leppek, Kathrin, Byeon, Gun Woo, Kladwang, Wipapat, Wayment-Steele, Hannah K., Kerr, Craig H., Xu, Adele F., Kim, Do Soon, Topkar, Ved V., Choe, Christian, Rothschild, Daphna, Tiu, Gerald C., Wellington-Oguri, Roger, Fujii, Kotaro, Sharma, Eesha, Watkins, Andrew M., Nicol, John J., Romano, Jonathan, Tunguz, Bojan, Diaz, Fernando, Cai, Hui, Guo, Pengbo, Wu, Jiewei, Meng, Fanyu, Shi, Shuai, Participants, Eterna, Dormitzer, Philip R., Solórzano, Alicia, Barna, Maria, Das, Rhiju
Published in Nature communications (22.03.2022)
Published in Nature communications (22.03.2022)
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Hemagglutinin (HA) Proteins from H1 and H3 Serotypes of Influenza A Viruses Require Different Antigen Designs for the Induction of Optimal Protective Antibody Responses as Studied by Codon-Optimized HA DNA Vaccines
Wang, Shixia, Taaffe, Jessica, Parker, Christopher, Solórzano, Alicia, Cao, Hong, García-Sastre, Adolfo, Lu, Shan
Published in Journal of Virology (01.12.2006)
Published in Journal of Virology (01.12.2006)
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Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility
Hai, Rong, Schmolke, Mirco, Leyva-Grado, Victor H., Thangavel, Rajagowthamee R., Margine, Irina, Jaffe, Eric L., Krammer, Florian, Solórzano, Alicia, García-Sastre, Adolfo, Palese, Peter, Bouvier, Nicole M.
Published in Nature communications (10.12.2013)
Published in Nature communications (10.12.2013)
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Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza
STEEL, John, LOWEN, Anice C, PENA, Lindomar, ANGEL, Matthew, SOLORZANO, Alicia, ALBRECHT, Randy, PEREZ, Daniel R, GARCIA-SASTRE, Adolfo, PALESE, Peter
Published in Journal of Virology (15.02.2009)
Published in Journal of Virology (15.02.2009)
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Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission
Tumpey, Terrence M, Maines, Taronna R, Van Hoeven, Neal, Glaser, Laurel, Solórzano, Alicia, Pappas, Claudia, Cox, Nancy J, Swayne, David E, Palese, Peter, Katz, Jacqueline M, García-Sastre, Adolfo
Published in Science (American Association for the Advancement of Science) (02.02.2007)
Published in Science (American Association for the Advancement of Science) (02.02.2007)
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A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial
Nachbagauer, Raffael, Feser, Jodi, Naficy, Abdollah, Bernstein, David I., Guptill, Jeffrey, Walter, Emmanuel B., Berlanda-Scorza, Franceso, Stadlbauer, Daniel, Wilson, Patrick C., Aydillo, Teresa, Behzadi, Mohammad Amin, Bhavsar, Disha, Bliss, Carly, Capuano, Christina, Carreño, Juan Manuel, Chromikova, Veronika, Claeys, Carine, Coughlan, Lynda, Freyn, Alec W., Gast, Christopher, Javier, Andres, Jiang, Kaijun, Mariottini, Chiara, McMahon, Meagan, McNeal, Monica, Solórzano, Alicia, Strohmeier, Shirin, Sun, Weina, Van der Wielen, Marie, Innis, Bruce L., García-Sastre, Adolfo, Palese, Peter, Krammer, Florian
Published in Nature medicine (01.01.2021)
Published in Nature medicine (01.01.2021)
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Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus
Tumpey, Terrence M, Basler, Christopher F, Aguilar, Patricia V, Zeng, Hui, Solórzano, Alicia, Swayne, David E, Cox, Nancy J, Katz, Jacqueline M, Taubenberger, Jeffery K, Palese, Peter, García-Sastre, Adolfo
Published in Science (American Association for the Advancement of Science) (07.10.2005)
Published in Science (American Association for the Advancement of Science) (07.10.2005)
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Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model
Liu, Wen-Chun, Nachbagauer, Raffael, Stadlbauer, Daniel, Solórzano, Alicia, Berlanda-Scorza, Francesco, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Albrecht, Randy A
Published in Frontiers in immunology (10.04.2019)
Published in Frontiers in immunology (10.04.2019)
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Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial
Bernstein, David I, Guptill, Jeffrey, Naficy, Abdollah, Nachbagauer, Raffael, Berlanda-Scorza, Francesco, Feser, Jodi, Wilson, Patrick C, Solórzano, Alicia, Van der Wielen, Marie, Walter, Emmanuel B, Albrecht, Randy A, Buschle, Kristen N, Chen, Yao-qing, Claeys, Carine, Dickey, Michelle, Dugan, Haley L, Ermler, Megan E, Freeman, Debra, Gao, Min, Gast, Christopher, Guthmiller, Jenna J, Hai, Rong, Henry, Carole, Lan, Linda Yu-Ling, McNeal, Monica, Palm, Anna-Karin E, Shaw, Dustin G, Stamper, Christopher T, Sun, Weina, Sutton, Victoria, Tepora, Micah E, Wahid, Rahnuma, Wenzel, Heather, Wohlbold, Teddy John, Innis, Bruce L, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian
Published in The Lancet infectious diseases (01.01.2020)
Published in The Lancet infectious diseases (01.01.2020)
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Mutations in the NS1 Protein of Swine Influenza Virus Impair Anti-Interferon Activity and Confer Attenuation in Pigs
Solorzano, Alicia, Webby, Richard J, Lager, Kelly M, Janke, Bruce H, Garcia-Sastre, Adolfo, Richt, Jurgen A
Published in Journal of Virology (01.06.2005)
Published in Journal of Virology (01.06.2005)
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Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility
Hai, Rong, Schmolke, Mirco, Leyva-Grado, Victor H., Thangavel, Rajagowthamee R., Margine, Irina, Jaffe, Eric L., Krammer, Florian, Solórzano, Alicia, García-Sastre, Adolfo, Palese, Peter, Bouvier, Nicole M.
Published in Nature communications (10.12.2013)
Published in Nature communications (10.12.2013)
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Reactogenicity, safety, and immunogenicity of chimeric haemagglutinin influenza split-virion vaccines, adjuvanted with AS01 or AS03 or non-adjuvanted: a phase 1–2 randomised controlled trial
Folschweiller, Nicolas, Vanden Abeele, Carline, Chu, Laurence, Van Damme, Pierre, García-Sastre, Adolfo, Krammer, Florian, Nachbagauer, Raffael, Palese, Peter, Solórzano, Alicia, Bi, Dan, David, Marie-Pierre, Friel, Damien, Innis, Bruce L, Koch, Juliane, Mallett, Corey P, Rouxel, Ronan Nicolas, Salaun, Bruno, Vantomme, Valerie, Verheust, Céline, Struyf, Frank
Published in The Lancet infectious diseases (01.07.2022)
Published in The Lancet infectious diseases (01.07.2022)
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Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
Grimm, Daniel, Staeheli, Peter, Hufbauer, Martin, Koerner, Iris, Martínez-Sobrido, Luis, Solórzano, Alicia, García-Sastre, Adolfo, Haller, Otto, Kochs, Georg
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2007)
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Vaccination of Pigs against Swine Influenza Viruses by Using an NS1-Truncated Modified Live-Virus Vaccine
Richt, J.A, Lekcharoensuk, P, Lager, K.M, Vincent, A.L, Loiacono, C.M, Janke, B.H, Wu, W.H, Yoon, K.J, Webby, R.J, Solorzano, A
Published in Journal of Virology (01.11.2006)
Published in Journal of Virology (01.11.2006)
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Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus
Pappas, Claudia, Aguilar, Patricia V, Basler, Christopher F, Solórzano, Alicia, Zeng, Hui, Perrone, Lucy A, Palese, Peter, García-Sastre, Adolfo, Katz, Jacqueline M, Tumpey, Terrence M
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
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A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies
Nachbagauer, Raffael, Liu, Wen-Chun, Choi, Angela, Wohlbold, Teddy John, Atlas, Talia, Rajendran, Madhusudan, Solórzano, Alicia, Berlanda-Scorza, Francesco, García-Sastre, Adolfo, Palese, Peter, Albrecht, Randy A., Krammer, Florian
Published in npj vaccines (14.09.2017)
Published in npj vaccines (14.09.2017)
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Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model
Liu, Wen-Chun, Nachbagauer, Raffael, Stadlbauer, Daniel, Strohmeier, Shirin, Solórzano, Alicia, Berlanda-Scorza, Francesco, Innis, Bruce L, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Albrecht, Randy A
Published in Vaccines (Basel) (11.01.2021)
Published in Vaccines (Basel) (11.01.2021)
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Heterologous HA DNA vaccine prime—inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 or H3 serotype influenza viruses
Wang, Shixia, Parker, Chris, Taaffe, Jessica, Solórzano, Alicia, García-Sastre, Adolfo, Lu, Shan
Published in Vaccine (04.07.2008)
Published in Vaccine (04.07.2008)
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