Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD
Softic, Samir, Boucher, Jeremie, Solheim, Marie H, Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P, Winnay, Jonathon, Perez-Atayde, Antonio R, Kahn, C Ronald
Published in Diabetes (New York, N.Y.) (01.08.2016)
Published in Diabetes (New York, N.Y.) (01.08.2016)
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Journal Article
Inhibition of the PI 3-kinase pathway disrupts the unfolded protein response and reduces sensitivity to ER stress-dependent apoptosis
Winnay, Jonathon N, Solheim, Marie H, Sakaguchi, Masaji, Njølstad, Pål R, Kahn, C Ronald
Published in The FASEB journal (01.09.2020)
Published in The FASEB journal (01.09.2020)
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Journal Article
246-LB: Rare Noncoding Intronic HNF1A Sequence Variants Cause Aberrant mRNA Processing in MODY
SOLHEIM, MARIE H., KHAKIANI, MOJDEH NASROLLAHZADEH, MOLNES, JANNE, AUKRUST, INGVILD, NJøLSTAD, PåL RASMUS, JOHANSSON, STEFAN
Published in Diabetes (New York, N.Y.) (01.06.2019)
Published in Diabetes (New York, N.Y.) (01.06.2019)
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Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes
Svalastoga, Pernille, Kaci, Alba, Molnes, Janne, Solheim, Marie H., Johansson, Bente B., Krogvold, Lars, Skrivarhaug, Torild, Valen, Eivind, Johansson, Stefan, Molven, Anders, Sagen, Jørn V., Søfteland, Eirik, Bjørkhaug, Lise, Tjora, Erling, Aukrust, Ingvild, Njølstad, Pål R.
Published in Diabetologia (01.12.2023)
Published in Diabetologia (01.12.2023)
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Journal Article
PI3-kinase mutation linked to insulin and growth factor resistance in vivo
Winnay, Jonathon N, Solheim, Marie H, Dirice, Ercument, Sakaguchi, Masaji, Noh, Hye-Lim, Kang, Hee Joon, Takahashi, Hirokazu, Chudasama, Kishan K, Kim, Jason K, Molven, Anders, Kahn, C Ronald, Njølstad, Pål R
Published in The Journal of clinical investigation (01.04.2016)
Published in The Journal of clinical investigation (01.04.2016)
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Journal Article
Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD
Park, Se-Hyung, Helsley, Robert N., Fadhul, Taghreed, Willoughby, Jennifer L.S., Noetzli, Leila, Tu, Ho-Chou, Solheim, Marie H., Fujisaka, Shiho, Pan, Hui, Dreyfuss, Jonathan M., Bons, Joanna, Rose, Jacob, King, Christina D., Schilling, Birgit, Lusis, Aldons J., Pan, Calvin, Gupta, Manoj, Kulkarni, Rohit N., Fitzgerald, Kevin, Kern, Philip A., Divanovic, Senad, Kahn, C. Ronald, Softic, Samir
Published in Metabolism, clinical and experimental (01.08.2023)
Published in Metabolism, clinical and experimental (01.08.2023)
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Journal Article
Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes
Solheim, Marie H, Winnay, Jonathon N, Batista, Thiago M, Molven, Anders, Njølstad, Pål R, Kahn, C Ronald
Published in Diabetes (New York, N.Y.) (01.07.2018)
Published in Diabetes (New York, N.Y.) (01.07.2018)
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Journal Article
The E3 SUMO ligase PIASγ is a novel interaction partner regulating the activity of diabetes associated hepatocyte nuclear factor-1α
Kaci, Alba, Keindl, Magdalena, Solheim, Marie H., Njølstad, Pål R., Bjørkhaug, Lise, Aukrust, Ingvild
Published in Scientific reports (24.08.2018)
Published in Scientific reports (24.08.2018)
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Journal Article
Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase
Solheim, Marie H, Clermont, Allen C, Winnay, Jonathon N, Hallstensen, Erlend, Molven, Anders, Njølstad, Pål R, Rødahl, Eyvind, Kahn, C Ronald
Published in Investigative ophthalmology & visual science (01.06.2017)
Published in Investigative ophthalmology & visual science (01.06.2017)
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Journal Article
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice
Fjeld, Karianne, Gravdal, Anny, Brekke, Ranveig S., Alam, Jahedul, Wilhelm, Steven J., El Jellas, Khadija, Pettersen, Helene N., Lin, Jianguo, Solheim, Marie H., Steine, Solrun J., Johansson, Bente B., Njølstad, Pål R., Verbeke, Caroline S., Xiao, Xunjun, Lowe, Mark E., Molven, Anders
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
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Journal Article
Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD
Park, Se-Hyung, Helsley, Robert N, Fadhul, Taghreed, Willoughby, Jennifer L S, Noetzli, Leila, Tu, Ho-Chou, Solheim, Marie H, Fujisaka, Shiho, Pan, Hui, Dreyfuss, Jonathan M, Bons, Joanna, Rose, Jacob, King, Christina D, Schilling, Birgit, Lusis, Aldons J, Pan, Calvin, Gupta, Manoj, Kulkarni, Rohit N, Fitzgerald, Kevin, Kern, Philip A, Divanovic, Senad, Kahn, C Ronald, Softic, Samir
Published in bioRxiv (27.01.2023)
Published in bioRxiv (27.01.2023)
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GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation
Negahdar, Maria, Aukrust, Ingvild, Molnes, Janne, Solheim, Marie H., Johansson, Bente B., Sagen, Jørn V., Dahl-Jørgensen, Knut, Kulkarni, Rohit N., Søvik, Oddmund, Flatmark, Torgeir, Njølstad, Pål R., Bjørkhaug, Lise
Published in Molecular and cellular endocrinology (25.01.2014)
Published in Molecular and cellular endocrinology (25.01.2014)
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Journal Article
Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD
Softic, Samir, Boucher, Jeremie, Solheim, Marie H, Fujisaka, Shiho, Haering, Max-Felix, Homan, Erica P, Winnay, Jonathon, Perez-Atayde, Antonio R, Kahn, C Ronald
Published in Diabetes (New York, N.Y.) (01.08.2016)
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Published in Diabetes (New York, N.Y.) (01.08.2016)
Journal Article
P13-kinase mutation linked to insulin and growth factor resistance in vivo
Winnay, Jonathon N, Solheim, Marie H, Dirice, Ercument, Sakaguchi, Masaji, Noh, Hye-Lim, Kang, Hee Joon, Takahashi, Hirokazu, Chudasama, Kishan K, Kim, Jason K, Molven, Anders, Kahn, C. Ronald, Njolstad, Pal R
Published in The Journal of clinical investigation (01.04.2016)
Published in The Journal of clinical investigation (01.04.2016)
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Journal Article