The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells
Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Solé, Sònia, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Muñoz-Pinedo, Cristina, Yoldi, Guillermo, Abad, Jose L, Segura, Miguel F, Moran, Teresa, Romeo, Margarita, Bosch-Barrera, Joaquim, Oaknin, Ana, Alfón, Jose, Domènech, Carles, Fabriàs, Gemma, Velasco, Guillermo, Lizcano, Jose M
Published in Autophagy (03.06.2021)
Published in Autophagy (03.06.2021)
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Journal Article
The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer
López‐Plana, Anna, Fernández‐Nogueira, Patricia, Muñoz‐Guardiola, Pau, Solé‐Sánchez, Sònia, Megías‐Roda, Elisabet, Pérez‐Montoyo, Héctor, Jauregui, Patricia, Yeste‐Velasco, Marc, Gómez‐Ferreria, Mariana, Erazo, Tatiana, Ametller, Elisabet, Recalde‐Percaz, Leire, Moragas‐Garcia, Núria, Noguera‐Castells, Aleix, Mancino, Mario, Morán, Teresa, Nadal, Ernest, Alfón, José, Domènech, Carles, Gascon, Pere, Lizcano, Jose M., Fuster, Gemma, Bragado, Paloma
Published in International journal of cancer (15.08.2020)
Published in International journal of cancer (15.08.2020)
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Journal Article
ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple‐negative breast cancer models
Polonio‐Alcalá, Emma, Solé‐Sánchez, Sònia, Muñoz‐Guardiola, Pau, Megías‐Roda, Elisabet, Perez‐Montoyo, Héctor, Yeste‐Velasco, Marc, Alfón, Jose, Lizcano, Jose Miguel, Domènech, Carles, Ruiz‐Martínez, Santiago, Puig, Teresa
Published in Cancer communications (London, England) (01.06.2022)
Published in Cancer communications (London, England) (01.06.2022)
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Journal Article
Neutrophil Infiltration Increases Matrix Metalloproteinase-9 in the Ischemic Brain after Occlusion/Reperfusion of the Middle Cerebral Artery in Rats
Justicia, Carles, Panés, Julián, Solé, Sónia, Cervera, Álvaro, Deulofeu, Ramon, Chamorro, Ángel, Planas, Anna M.
Published in Journal of cerebral blood flow and metabolism (01.12.2003)
Published in Journal of cerebral blood flow and metabolism (01.12.2003)
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Journal Article
A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer
Martínez-Høyer, Sergio, Solé-Sánchez, Sònia, Aguado, Fernando, Martínez-Martínez, Sara, Serrano-Candelas, Eva, Hernández, José Luis, Iglesias, Mar, Redondo, Juan Miguel, Casanovas, Oriol, Messeguer, Ramon, Pérez-Riba, Mercè
Published in Carcinogenesis (New York) (01.07.2015)
Published in Carcinogenesis (New York) (01.07.2015)
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Journal Article
Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer
Felip, Isidre, Moiola, Cristian Pablo, Megino-Luque, Cristina, Lopez-Gil, Carlos, Cabrera, Silvia, Solé-Sánchez, Sonia, Muñoz-Guardiola, Pau, Megias-Roda, Elisabet, Pérez-Montoyo, Héctor, Alfon, José, Yeste-Velasco, Marc, Santacana, María, Dolcet, Xavier, Reques, Armando, Oaknin, Ana, Rodríguez-Freixinos, Victor, Lizcano, José Miguel, Domènech, Carles, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Colas, Eva, Eritja, Nuria
Published in Gynecologic oncology (01.05.2019)
Published in Gynecologic oncology (01.05.2019)
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Journal Article
Development of TRIB3 as a novel preclinical and clinical pharmacodynamic biomarker for ABTL0812
Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Solé-Sánchez, Sònia, Bragado, Paloma, Colàs-Ortega, Eva, Eritja, Nuria, Lopez-Plana, Anna, Fernandez-Nogueira, Patricia, Muñoz-Guardiola, Pau, Megías-Roda, Elisabet, Moiola, Cristian, Felip, Isidre, Nadal-Alforja, Ernest, Gil Martin, Marta, Romeo, Margarita, Moran, Teresa, Gil-Moreno, Antonio, Matias-Guiu, Xavier, Domenech, Carles, Lizcano, Jose M
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Estimation of Gelatinase Content in Rat Brain: Effect of Focal Ischemia
Planas, Anna M., Solé, Sònia, Justicia, Carles, Farré, Eduard Rodríguez
Published in Biochemical and biophysical research communications (30.11.2000)
Published in Biochemical and biophysical research communications (30.11.2000)
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Journal Article
Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation
Fiorentino, Francesco Paolo, Tokgün, Elvan, Solé-Sánchez, Sònia, Giampaolo, Sabrina, Tokgün, Onur, Jauset, Toni, Kohno, Takashi, Perucho, Manuel, Soucek, Laura, Yokota, Jun
Published in Oncotarget (24.05.2016)
Published in Oncotarget (24.05.2016)
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Journal Article
Certain Forms of Matrix Metalloproteinase-9 Accumulate in the Extracellular Space After Microdialysis Probe Implantation and Middle Cerebral Artery Occlusion/Reperfusion
Planas, Anna M., Justicia, Carles, Solé, Sònia, Friguls, Bibiana, Cervera, Álvaro, Adell, Albert, Chamorro, Ángel
Published in Journal of cerebral blood flow and metabolism (01.08.2002)
Published in Journal of cerebral blood flow and metabolism (01.08.2002)
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Journal Article
A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer
Martínez-Høyer, Sergio, Solé-Sánchez, Sònia, Aguado, Fernando, Martínez-Martínez, Sara, Serrano-Candelas, Eva, Hernández, José Luis, Iglesias, Mar, Redondo, Juan Miguel, Casanovas, Oriol, Messeguer, Ramon, Pérez-Riba, Mercè
Published in Carcinogenesis (New York) (01.07.2015)
Published in Carcinogenesis (New York) (01.07.2015)
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Journal Article
RCAN 1 and 3 proteins regulate thymic positive selection
Serrano-Candelas, Eva, Alemán-Muench, Germán, Solé-Sánchez, Sònia, Aubareda, Anna, Martínez-Høyer, Sergio, Adán, Jaume, Aranguren-Ibáñez, Álvaro, Pritchard, Melanie A., Soldevila, Gloria, Pérez-Riba, Mercè
Published in Biochemical and biophysical research communications (01.05.2015)
Published in Biochemical and biophysical research communications (01.05.2015)
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Journal Article
Abstract 1234: The anticancer drug ABTL0812 induces cancer cell death by impairing Akt/mTORC1 axis and inducing ER stress-mediated cytotoxic autophagy
Muñoz-Guardiola, Pau, Casas, Josefina, Megías-Roda, Elisabet, Perez-Montoyo, Hector, Solé-Sánchez, Sonia, Yeste-Velasco, Marc, Erazo, Tatiana, Diéguez-Martínez, Nora, Espinosa-Gil, Sergio, Yoldi, Guillermo, Muñoz-Pinedo, Cristina, Segura, Miguel F., Alfon, Jose, Fabriàs, Gemma, Velasco, Guillermo, Domenech, Carles, Lizcano, Jose M.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
The first-in-class anti-cancer agent ABTL0812 is effective in preclinical models of human endometrial cancer
Colàs, Eva Colàs, Eritja, Nuria, Muñoz-Guardiola, Pau, Sole-Sanchez, Sonia, Moiola, Cristian, Felip, Isidre, Gil-Moreno, Antonio, Perez-Montoyo, Hector, Alfon, Jose Alberto, Domenech, Carles, Lizcano, Jose M, Matias-Guiu, Xavier
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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