The Trypanocidal Activity of Amidine Compounds Does Not Correlate with Their Binding Affinity to Trypanosoma cruzi Kinetoplast DNA
DALIRY, A, PIRES, M. Q, AKAY, S, SOM, P, HU, Q, BOYKIN, D. W, WILSON, W. D, DE CASTRO, S. L, SOEIRO, M. N. C, SILVA, C. F, PACHECO, R. S, MUNDE, M, STEPHENS, C. E, KUMAR, A, ISMAIL, M. A, LIU, Z, FARAHAT, A. A
Published in Antimicrobial Agents and Chemotherapy (01.10.2011)
Published in Antimicrobial Agents and Chemotherapy (01.10.2011)
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Cellular Effects of Reversed Amidines on Trypanosoma cruzi
SILVA, C. F, MEUSER, M. B, DE SOUZA, E. M, MEIRELLES, M. N. L, STEPHENS, C. E, SOM, P, BOYKIN, D. W, SOEIRO, M. N. C
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
Published in Antimicrobial Agents and Chemotherapy (01.11.2007)
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Repurposing Strategy of Atorvastatin against Trypanosoma cruzi: In Vitro Monotherapy and Combined Therapy with Benznidazole Exhibit Synergistic Trypanocidal Activity
Araujo-Lima, C F, Peres, R B, Silva, P B, Batista, M M, Aiub, C A F, Felzenszwalb, I, Soeiro, M N C
Published in Antimicrobial agents and chemotherapy (01.09.2018)
Published in Antimicrobial agents and chemotherapy (01.09.2018)
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Antitrypanosomal Activity of Sterol 14α-Demethylase (CYP51) Inhibitors VNI and VFV in the Swiss Mouse Models of Chagas Disease Induced by the Trypanosoma cruzi Y Strain
Guedes-da-Silva, F H, Batista, D G J, Da Silva, C F, De Araújo, J S, Pavão, B P, Simões-Silva, M R, Batista, M M, Demarque, K C, Moreira, O C, Britto, C, Lepesheva, G I, Soeiro, M N C
Published in Antimicrobial agents and chemotherapy (01.04.2017)
Published in Antimicrobial agents and chemotherapy (01.04.2017)
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In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines
Nefertiti, A S G, Batista, M M, Da Silva, P B, Batista, D G J, Da Silva, C F, Peres, R B, Torres-Santos, E C, Cunha-Junior, E F, Holt, E, Boykin, D W, Brun, R, Wenzler, T, Soeiro, M N C
Published in Antimicrobial agents and chemotherapy (01.02.2018)
Published in Antimicrobial agents and chemotherapy (01.02.2018)
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Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi
Simões-Silva, M R, Nefertiti, A S G, De Araújo, J S, Batista, M M, Da Silva, P B, Bahia, M T, Menna-Barreto, R S, Pavão, B P, Green, J, Farahat, A A, Kumar, A, Boykin, D W, Soeiro, M N C
Published in Antimicrobial agents and chemotherapy (01.08.2016)
Published in Antimicrobial agents and chemotherapy (01.08.2016)
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In Vitro and In Vivo Trypanosomicidal Action of Novel Arylimidamides against Trypanosoma cruzi
Guedes-da-Silva, F H, Batista, D G J, Meuser, M B, Demarque, K C, Fulco, T O, Araújo, J S, Da Silva, P B, Da Silva, C F, Patrick, D A, Bakunova, S M, Bakunov, S A, Tidwell, R R, Oliveira, G M, Britto, C, Moreira, O C, Soeiro, M N C
Published in Antimicrobial agents and chemotherapy (01.04.2016)
Published in Antimicrobial agents and chemotherapy (01.04.2016)
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In Vitro and In Vivo Studies of the Biological Activity of Novel Arylimidamides against Trypanosoma cruzi
DE ARAUJO, J. S, DA SILVA, C. F, STEPHENS, C. E, KUMAR, A, BOYKIN, D. W, SOEIRO, M. N. C, BATISTA, D. G. J, DA SILVA, P. B, MEUSER, M. B, AIUB, C. A. F, DA SILVA, M. F. V, ARAUJO-LIMA, C. F, BANERJEE, M, FARAHAT, A. A
Published in Antimicrobial agents and chemotherapy (01.07.2014)
Published in Antimicrobial agents and chemotherapy (01.07.2014)
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Biological, ultrastructural effect and subcellular localization of aromatic diamidines in Trypanosoma cruzi
BATISTA, D. G. J., PACHECO, M. G. O., KUMAR, A., BRANOWSKA, D., ISMAIL, M. A., HU, L., BOYKIN, D. W., SOEIRO, M. N. C.
Published in Parasitology (01.02.2010)
Published in Parasitology (01.02.2010)
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Novel amidines and analogues as promising agents against intracellular parasites: a systematic review
SOEIRO, M. N. C., WERBOVETZ, K., BOYKIN, D. W., WILSON, W. D., WANG, M. Z., HEMPHILL, A.
Published in Parasitology (01.07.2013)
Published in Parasitology (01.07.2013)
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Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi
De Souza, E.M., da Silva, P.B., Nefertiti, A.S.G., Ismail, M.A., Arafa, R.K., Tao, B., Nixon-Smith, C.K., Boykin, D.W., Soeiro, M.N.C.
Published in Experimental parasitology (01.02.2011)
Published in Experimental parasitology (01.02.2011)
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Antiparasitic activity of aromatic diamidines is related to apoptosis-like death in Trypanosoma cruzi
DE SOUZA, E. M., MENNA-BARRETO, R., ARAÚJO-JORGE, T. C., KUMAR, A., HU, Q., BOYKIN, D. W., SOEIRO, M. N. C.
Published in Parasitology (01.07.2006)
Published in Parasitology (01.07.2006)
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Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi
Simões-Silva, M. R., De Araújo, J. S., Peres, R. B., Da Silva, P. B., Batista, M. M., De Azevedo, L. D., Bastos, M. M., Bahia, M. T., Boechat, N., Soeiro, M. N. C.
Published in Parasitology (01.07.2019)
Published in Parasitology (01.07.2019)
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Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy
Simões-Silva, M.R., De Araújo, J.S., Oliveira, G.M., Demarque, K.C., Peres, R.B., D'Almeida-Melo, I., Batista, D.G.J., Da Silva, C.F., Cardoso-Santos, C., Da Silva, P.B., Batista, M.M., Bahia, M.T., Soeiro, M.N.C.
Published in Biochemical pharmacology (01.12.2017)
Published in Biochemical pharmacology (01.12.2017)
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Increased Trypanosoma cruzi Invasion and Heart Fibrosis Associated with High Transforming Growth Factor β Levels in Mice Deficient in α2-Macroglobulin
WAGHABI, M. C, COUTINHO, C. M. L. M, SOEIRO, M. N. C, PEREIRA, M. C. S, FEIGE, J.-J, KERAMIDAS, M, COSSON, A, MINOPRIO, P, VAN LEUVEN, F, ARAUJO-JORGE, T. C
Published in Infection and Immunity (01.09.2002)
Published in Infection and Immunity (01.09.2002)
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The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I
Schmidt, T J, Khalid, S A, Romanha, A J, Alves, T Ma, Biavatti, M W, Brun, R, Da Costa, F B, de Castro, S L, Ferreira, V F, de Lacerda, M V G, Lago, J H G, Leon, L L, Lopes, N P, das Neves Amorim, R C, Niehues, M, Ogungbe, I V, Pohlit, A M, Scotti, M T, Setzer, W N, de N C Soeiro, M, Steindel, M, Tempone, A G
Published in Current medicinal chemistry (01.05.2012)
Published in Current medicinal chemistry (01.05.2012)
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The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part II
Schmidt, T J, Khalid, S A, Romanha, A J, Alves, T Ma, Biavatti, M W, Brun, R, Da Costa, F B, de Castro, S L, Ferreira, V F, de Lacerda, M V G, Lago, J H G, Leon, L L, Lopes, N P, das Neves Amorim, R C, Niehues, M, Ogungbe, I V, Pohlit, A M, Scotti, M T, Setzer, W N, de N C Soeiro, M, Steindel, M, Tempone, A G
Published in Current medicinal chemistry (01.05.2012)
Published in Current medicinal chemistry (01.05.2012)
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In vitro investigation of the efficacy of novel diamidines against Trypanosoma cruzi
TIMM, B. L., DA SILVA, P. B., BATISTA, M. M., FARAHAT, A. A., KUMAR, A., BOYKIN, D. W., SOEIRO, M. N. C.
Published in Parasitology (01.09.2014)
Published in Parasitology (01.09.2014)
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