Administration of mucuna beans (Mucuna pruriences (L.) DC. var. utilis) improves cognition and neuropathology of 3 × Tg-AD mice
Konishi, Fumiko, Furusho, Tadasu, Soeda, Yoshiyuki, Yamauchi, Jun, Kobayashi, Shoko, Ito, Masatoshi, Araki, Takuma, Kogure, Sarasa, Takashima, Akihiko, Takekoshi, Susumu
Published in Scientific reports (19.01.2022)
Published in Scientific reports (19.01.2022)
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Journal Article
Enhanced Tau Protein Translation by Hyper-Excitation
Kobayashi, Shunsuke, Tanaka, Toru, Soeda, Yoshiyuki, Takashima, Akihiko
Published in Frontiers in aging neuroscience (20.11.2019)
Published in Frontiers in aging neuroscience (20.11.2019)
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Journal Article
A novel monoclonal antibody generated by immunization with granular tau oligomers binds to tau aggregates at 423-430 amino acid sequence
Soeda, Yoshiyuki, Hayashi, Emi, Nakatani, Naoko, Ishigaki, Shinsuke, Takaichi, Yuta, Tachibana, Taro, Riku, Yuichi, Chambers, James K, Koike, Riki, Mohammad, Moniruzzaman, Takashima, Akihiko
Published in Scientific reports (26.07.2024)
Published in Scientific reports (26.07.2024)
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Journal Article
Identification of key amino acids responsible for the distinct aggregation properties of microtubule‐associated protein 2 and tau
Xie, Ce, Soeda, Yoshiyuki, Shinzaki, Yuki, In, Yasuko, Tomoo, Koji, Ihara, Yasuo, Miyasaka, Tomohiro
Published in Journal of neurochemistry (01.10.2015)
Published in Journal of neurochemistry (01.10.2015)
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Journal Article
Research on the molecular mechanism of singularity phenomenon in neurological disorders
Bannai, Hiroko, Takashima, Akihiko, Soeda, Yoshiyuki, Yoshimura, Hideaki, Matsumoto, Gen, Sahara, Naruhiko, Hiroshima, Michio, Hattori, Mitsuru, Nagai, Takeharu
Published in Biophysics and Physicobiology (01.01.2024)
Published in Biophysics and Physicobiology (01.01.2024)
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Journal Article
Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory
Yoshikawa, Misato, Soeda, Yoshiyuki, Michikawa, Makoto, Almeida, Osborne F X, Takashima, Akihiko
Published in Frontiers in neuroscience (01.03.2018)
Published in Frontiers in neuroscience (01.03.2018)
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Journal Article
PE859, a novel tau aggregation inhibitor, reduces aggregated tau and prevents onset and progression of neural dysfunction in vivo
Okuda, Michiaki, Hijikuro, Ichiro, Fujita, Yuki, Wu, Xiaofeng, Nakayama, Shinichi, Sakata, Yoko, Noguchi, Yuji, Ogo, Makoto, Akasofu, Shigeru, Ito, Yoshimasa, Soeda, Yoshiyuki, Tsuchiya, Nobuhiko, Tanaka, Naoki, Takahashi, Takashi, Sugimoto, Hachiro
Published in PloS one (06.02.2015)
Published in PloS one (06.02.2015)
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Journal Article
Amyloid β and tau pathology in brains of aged pinniped species (sea lion, seal, and walrus)
Takaichi, Yuta, Chambers, James K, Takahashi, Kei, Soeda, Yoshiyuki, Koike, Riki, Katsumata, Etsuko, Kita, Chiaki, Matsuda, Fuko, Haritani, Makoto, Takashima, Akihiko, Nakayama, Hiroyuki, Uchida, Kazuyuki
Published in Acta neuropathologica communications (07.01.2021)
Published in Acta neuropathologica communications (07.01.2021)
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Journal Article
A novel plasma p-tau181 assay as a specific biomarker of tau pathology in Alzheimer's disease
Tagai, Kenji, Tatebe, Harutsugu, Matsuura, Sayo, Hong, Zhang, Kokubo, Naomi, Matsuoka, Kiwamu, Endo, Hironobu, Oyama, Asaka, Hirata, Kosei, Shinotoh, Hitoshi, Kataoka, Yuko, Matsumoto, Hideki, Oya, Masaki, Kurose, Shin, Takahata, Keisuke, Ichihashi, Masanori, Kubota, Manabu, Seki, Chie, Shimada, Hitoshi, Takado, Yuhei, Kawamura, Kazunori, Zhang, Ming-Rong, Soeda, Yoshiyuki, Takashima, Akihiko, Higuchi, Makoto, Tokuda, Takahiko
Published in Translational neurodegeneration (03.09.2024)
Published in Translational neurodegeneration (03.09.2024)
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Journal Article
Modification of Tau by 8-Nitroguanosine 3′,5′-Cyclic Monophosphate (8-Nitro-cGMP)
Yoshitake, Jun, Soeda, Yoshiyuki, Ida, Tomoaki, Sumioka, Akio, Yoshikawa, Misato, Matsushita, Kenji, Akaike, Takaaki, Takashima, Akihiko
Published in The Journal of biological chemistry (01.10.2016)
Published in The Journal of biological chemistry (01.10.2016)
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Journal Article
Impact of Transgenic Overexpression of SH2-Containing Inositol 5′-Phosphatase 2 on Glucose Metabolism and Insulin Signaling in Mice
Kagawa, Syota, Soeda, Yoshiyuki, Ishihara, Hajime, Oya, Takeshi, Sasahara, Masakiyo, Yaguchi, Saori, Oshita, Ryo, Wada, Tsutomu, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Published in Endocrinology (Philadelphia) (01.02.2008)
Published in Endocrinology (Philadelphia) (01.02.2008)
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Journal Article
The Inositol Phosphatase SHIP2 Negatively Regulates Insulin/IGF-I Actions Implicated in Neuroprotection and Memory Function in Mouse Brain
Soeda, Yoshiyuki, Tsuneki, Hiroshi, Muranaka, Hayato, Mori, Norihiko, Hosoh, Shuji, Ichihara, Yoshinori, Kagawa, Syota, Wang, Xu, Toyooka, Naoki, Takamura, Yusaku, Uwano, Teruko, Nishijo, Hisao, Wada, Tsutomu, Sasaoka, Toshiyasu
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2010)
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2010)
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Journal Article
Adaptive responses to alloxan‐induced mild oxidative stress ameliorate certain tauopathy phenotypes
Yoshiike, Yuji, Yamashita, Shunji, Mizoroki, Tatsuya, Maeda, Sumihiro, Murayama, Miyuki, Kimura, Tetsuya, Sahara, Naruhiko, Soeda, Yoshiyuki, Takashima, Akihiko
Published in Aging cell (01.02.2012)
Published in Aging cell (01.02.2012)
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Journal Article
Methylene Blue Inhibits Formation of Tau Fibrils but not of Granular Tau Oligomers: A Plausible Key to Understanding Failure of a Clinical Trial for Alzheimer's Disease
Soeda, Yoshiyuki, Saito, Marino, Maeda, Sumihiro, Ishida, Kohki, Nakamura, Akira, Kojima, Shuichi, Takashima, Akihiko
Published in Journal of Alzheimer's disease (01.01.2019)
Published in Journal of Alzheimer's disease (01.01.2019)
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Journal Article
Intracellular tau fragment droplets serve as seeds for tau fibrils
Soeda, Yoshiyuki, Yoshimura, Hideaki, Bannai, Hiroko, Koike, Riki, Shiiba, Isshin, Takashima, Akihiko
Published in Structure (London) (12.07.2024)
Published in Structure (London) (12.07.2024)
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Journal Article