Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike – ACE2 complexes reveal distinct changes between both variants
Socher, Eileen, Heger, Lukas, Paulsen, Friedrich, Zunke, Friederike, Arnold, Philipp
Published in Computational and structural biotechnology journal (01.01.2022)
Published in Computational and structural biotechnology journal (01.01.2022)
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Journal Article
Mutations in the B.1.1.7 SARS-CoV-2 Spike Protein Reduce Receptor-Binding Affinity and Induce a Flexible Link to the Fusion Peptide
Socher, Eileen, Conrad, Marcus, Heger, Lukas, Paulsen, Friedrich, Sticht, Heinrich, Zunke, Friederike, Arnold, Philipp
Published in Biomedicines (08.05.2021)
Published in Biomedicines (08.05.2021)
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Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H
Schütz, Martin, Müller, Regina, Socher, Eileen, Wangen, Christina, Full, Florian, Wyler, Emanuel, Wong, Diana, Scherer, Myriam, Stamminger, Thomas, Chou, Sunwen, Rawlinson, William D., Hamilton, Stuart T., Sticht, Heinrich, Marschall, Manfred
Published in International journal of molecular sciences (01.10.2022)
Published in International journal of molecular sciences (01.10.2022)
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Journal Article
Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97
Schütz, Martin, Steingruber, Mirjam, Socher, Eileen, Müller, Regina, Wagner, Sabrina, Kögel, Merle, Sticht, Heinrich, Marschall, Manfred
Published in Viruses (27.06.2021)
Published in Viruses (27.06.2021)
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Understanding the Cytomegalovirus Cyclin-Dependent Kinase Ortholog pUL97 as a Multifaceted Regulator and an Antiviral Drug Target
Marschall, Manfred, Schütz, Martin, Wild, Markus, Socher, Eileen, Wangen, Christina, Dhotre, Kishore, Rawlinson, William D., Sticht, Heinrich
Published in Cells (Basel, Switzerland) (13.08.2024)
Published in Cells (Basel, Switzerland) (13.08.2024)
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Novel Homozygous FA2H Variant Causing the Full Spectrum of Fatty Acid Hydroxylase-Associated Neurodegeneration (SPG35)
German, Alexander, Jukic, Jelena, Laner, Andreas, Arnold, Philipp, Socher, Eileen, Mennecke, Angelika, Schmidt, Manuel A, Winkler, Jürgen, Abicht, Angela, Regensburger, Martin
Published in Genes (01.01.2024)
Published in Genes (01.01.2024)
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Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target
Tillmanns, Julia, Häge, Sigrun, Borst, Eva Maria, Wardin, Julia, Eickhoff, Jan, Klebl, Bert, Wagner, Sabrina, Wangen, Christina, Hahn, Friedrich, Socher, Eileen, Marschall, Manfred
Published in Cells (Basel, Switzerland) (01.04.2023)
Published in Cells (Basel, Switzerland) (01.04.2023)
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A New Immortalized Human Lacrimal Gland Cell Line
Gleixner, Sophie, Zahn, Ingrid, Dietrich, Jana, Singh, Swati, Drobny, Alice, Schneider, Yanni, Schwendner, Raphael, Socher, Eileen, Blavet, Nicolas, Bräuer, Lars, Gostian, Antoniu-Oreste, Balk, Matthias, Schulze-Tanzil, Gundula, Günther, Claudia, Paulsen, Friedrich, Arnold, Philipp
Published in Cells (Basel, Switzerland) (01.04.2024)
Published in Cells (Basel, Switzerland) (01.04.2024)
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Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins
Steingruber, Mirjam, Kraut, Alexandra, Socher, Eileen, Sticht, Heinrich, Reichel, Anna, Stamminger, Thomas, Amin, Bushra, Couté, Yohann, Hutterer, Corina, Marschall, Manfred
Published in Viruses (18.08.2016)
Published in Viruses (18.08.2016)
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Production and Secretion of Gelsolin by Both Human Macrophage- and Fibroblast-like Synoviocytes and GSN Modulation in the Synovial Fluid of Patients with Various Forms of Arthritis
Feldt, Jessica, Schicht, Martin, Welss, Jessica, Gelse, Kolja, Sesselmann, Stefan, Tsokos, Michael, Socher, Eileen, Garreis, Fabian, Müller, Thomas, Paulsen, Friedrich
Published in Biomedicines (21.03.2022)
Published in Biomedicines (21.03.2022)
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Journal Article
The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain
Steingruber, Mirjam, Socher, Eileen, Hutterer, Corina, Webel, Rike, Bergbrede, Tim, Lenac, Tihana, Sticht, Heinrich, Marschall, Manfred
Published in Viruses (11.08.2015)
Published in Viruses (11.08.2015)
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Computational decomposition reveals reshaping of the SARS‐CoV‐2–ACE2 interface among viral variants expressing the N501Y mutation
Socher, Eileen, Conrad, Marcus, Heger, Lukas, Paulsen, Friedrich, Sticht, Heinrich, Zunke, Friederike, Arnold, Philipp
Published in Journal of Cellular Biochemistry (01.12.2021)
Published in Journal of Cellular Biochemistry (01.12.2021)
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The role of triggering receptor expressed on myeloid cells 2 in Parkinson’s disease and other neurodegenerative disorders
Schwarz, Hannah, Bässler, Sarah, Balta, Denise, Socher, Eileen, Zunke, Friederike, Arnold, Philipp
Published in Behavioural brain research (05.09.2022)
Published in Behavioural brain research (05.09.2022)
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Journal Article
Cover Image, Volume 122, Number 12, December 2021
Socher, Eileen, Conrad, Marcus, Heger, Lukas, Paulsen, Friedrich, Sticht, Heinrich, Zunke, Friederike, Arnold, Philipp
Published in Journal of cellular biochemistry (01.12.2021)
Published in Journal of cellular biochemistry (01.12.2021)
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Journal Article
Structural and functional properties of meprin β metalloproteinase with regard to cell signaling
Li, Wenjia, Lückstädt, Wiebke, Wöhner, Birte, Bub, Simon, Schulz, Antonia, Socher, Eileen, Arnold, Philipp
Published in Biochimica et biophysica acta. Molecular cell research (01.01.2022)
Published in Biochimica et biophysica acta. Molecular cell research (01.01.2022)
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