Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects
Dymond, Angela W., MSc, Howes, Colin, PhD, Pattison, Christine, MChem (Hons), So, Karen, MD, Mariani, Gabriella, MD, Savage, Mark, BSc, Mair, Stuart, MBChB, Ford, Gill, BSc, Martin, Paul, PhD
Published in Clinical therapeutics (01.11.2016)
Published in Clinical therapeutics (01.11.2016)
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Evaluation of the Effect of Selumetinib on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled Crossover QT/QTc Study in Healthy Subjects
Zhou, Diansong, PhD, So, Karen, MD, Dymond, Angela W., MSc, Vik, Torbjorn, MD, Al-Huniti, Nidal, PhD, Mariani, Gabriella, MD, Zorenyi, Gyorgy, MD, Huang, Yifan, PhD, Holmes, Victoria, PhD, Severin, Paul, BSc, Rasmussen, Scott, MD, Martin, Paul, PhD
Published in Clinical therapeutics (01.12.2016)
Published in Clinical therapeutics (01.12.2016)
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Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-Label Studies
Dirix, Luc, MD, PhD, Swaisland, Helen, Verheul, Henk M.W., MD, PhD, Rottey, Sylvie, MD, PhD, Leunen, Karin, MD, Jerusalem, Guy, MD, PhD, Rolfo, Christian, MD, PhD, Nielsen, Dorte, MD, DMSc, Molife, L. Rhoda, BMedSci, BM BS, MRCP, MD, MSc, Kristeleit, Rebecca, BSc, MRCP, PhD, Vos-Geelen, Judith de, MD, PhD, Mau-Sørensen, Morten, MD, PhD, Soetekouw, Patricia, MD, van Herpen, Carla, MD, PhD, Fielding, Anitra, MBChB, So, Karen, MBBS, MRCS, MD, Bannister, Wendy, Plummer, Ruth, MD, D.Phil, FRCP
Published in Clinical therapeutics (01.10.2016)
Published in Clinical therapeutics (01.10.2016)
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