The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
Lukhele, Sabelo, Rabbo, Diala Abd, Guo, Mengdi, Shen, Jian, Elsaesser, Heidi J., Quevedo, Rene, Carew, Madeleine, Gadalla, Ramy, Snell, Laura M., Mahesh, Lawanya, Ciudad, M. Teresa, Snow, Bryan E., You-Ten, Annick, Haight, Jillian, Wakeham, Andrew, Ohashi, Pamela S., Mak, Tak W., Cui, Weiguo, McGaha, Tracy L., Brooks, David G.
Published in Immunity (Cambridge, Mass.) (13.12.2022)
Published in Immunity (Cambridge, Mass.) (13.12.2022)
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Journal Article
CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity
Snell, Laura M., MacLeod, Bethany L., Law, Jaclyn C., Osokine, Ivan, Elsaesser, Heidi J., Hezaveh, Kebria, Dickson, Russell J., Gavin, Marc A., Guidos, Cynthia J., McGaha, Tracy L., Brooks, David G.
Published in Immunity (Cambridge, Mass.) (16.10.2018)
Published in Immunity (Cambridge, Mass.) (16.10.2018)
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Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence
Cunningham, Cameron R, Champhekar, Ameya, Tullius, Michael V, Dillon, Barbara Jane, Zhen, Anjie, de la Fuente, Justin Rafael, Herskovitz, Jonathan, Elsaesser, Heidi, Snell, Laura M, Wilson, Elizabeth B, de la Torre, Juan Carlos, Kitchen, Scott G, Horwitz, Marcus A, Bensinger, Steven J, Smale, Stephen T, Brooks, David G
Published in PLoS pathogens (01.01.2016)
Published in PLoS pathogens (01.01.2016)
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Journal Article
Networking at the Level of Host Immunity: Immune Cell Interactions during Persistent Viral Infections
Ng, Cherie T., Snell, Laura M., Brooks, David G., Oldstone, Michael B.A.
Published in Cell host & microbe (12.06.2013)
Published in Cell host & microbe (12.06.2013)
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Journal Article
Overcoming CD4 Th1 Cell Fate Restrictions to Sustain Antiviral CD8 T Cells and Control Persistent Virus Infection
Snell, Laura M., Osokine, Ivan, Yamada, Douglas H., De la Fuente, Justin Rafael, Elsaesser, Heidi J., Brooks, David G.
Published in Cell reports (Cambridge) (20.09.2016)
Published in Cell reports (Cambridge) (20.09.2016)
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Journal Article
Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection
Osokine, Ivan, Snell, Laura M., Cunningham, Cameron R., Yamada, Douglas H., Wilson, Elizabeth B., Elsaesser, Heidi J., de la Torre, Juan Carlos, Brooks, David
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2014)
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Journal Article
Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection
Snell, Laura M., Xu, Wenxi, Abd-Rabbo, Diala, Boukhaled, Giselle, Guo, Mengdi, Macleod, Bethany L., Elsaesser, Heidi J., Hezaveh, Kebria, Alsahafi, Nirmin, Lukhele, Sabelo, Nejat, Sara, Prabhakaran, Ramanandan, Epelman, Slava, McGaha, Tracy L., Brooks, David G.
Published in Nature immunology (01.12.2021)
Published in Nature immunology (01.12.2021)
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Journal Article
Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection
Xu, Wenxi, Snell, Laura M., Guo, Mengdi, Boukhaled, Giselle, Macleod, Bethany L., Li, Ming, Tullius, Michael V., Guidos, Cynthia J., Tsao, Ming-Sound, Divangahi, Maziar, Horwitz, Marcus A., Liu, Jun, Brooks, David G.
Published in Immunity (Cambridge, Mass.) (09.03.2021)
Published in Immunity (Cambridge, Mass.) (09.03.2021)
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Journal Article
Breast implant-associated EBV-positive diffuse large B-cell lymphoma: Two case reports and literature review
Morgan, Sarah, Tremblay-LeMay, Rosemarie, Lipa, Joan E., Sur, Monalisa, Delabie, Jan, Imrie, Kevin, Crump, Michael, Snell, Laura J., Ghorab, Zeina
Published in Pathology, research and practice (01.10.2021)
Published in Pathology, research and practice (01.10.2021)
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Journal Article
Opposing Roles for TRAF1 in the Alternative versus Classical NF-κB Pathway in T Cells
McPherson, Ann J., Snell, Laura M., Mak, Tak W., Watts, Tania H.
Published in The Journal of biological chemistry (29.06.2012)
Published in The Journal of biological chemistry (29.06.2012)
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Journal Article
Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
Guo, Mengdi, Abd-Rabbo, Diala, Bertol, Bruna C., Carew, Madeleine, Lukhele, Sabelo, Snell, Laura M., Xu, Wenxi, Boukhaled, Giselle M., Elsaesser, Heidi, Halaby, Marie Jo, Hirano, Naoto, McGaha, Tracy L., Brooks, David G.
Published in Cell reports (Cambridge) (26.09.2023)
Published in Cell reports (Cambridge) (26.09.2023)
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Journal Article
Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection
Elsaesser, Heidi J., Mohtashami, Mahmood, Osokine, Ivan, Snell, Laura M., Cunningham, Cameron R., Boukhaled, Giselle M., McGavern, Dorian B., Zúñiga-Pflücker, Juan Carlos, Brooks, David G.
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (10.03.2020)
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Journal Article
A viral-specific CD4 + T cell response protects female mice from Coxsackievirus B3 infection
Pattnaik, Aryamav, Dhalech, Adeeba H, Condotta, Stephanie A, Corn, Caleb, Richer, Martin J, Snell, Laura M, Robinson, Christopher M
Published in Frontiers in immunology (11.01.2024)
Published in Frontiers in immunology (11.01.2024)
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Journal Article
T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy
Snell, Laura M., Lin, Gloria H. Y., McPherson, Ann J., Moraes, Theo J., Watts, Tania H.
Published in Immunological reviews (01.11.2011)
Published in Immunological reviews (01.11.2011)
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Journal Article
A network of immune and microbial modifications underlies viral persistence in the gastrointestinal tract
Macleod, Bethany L, Elsaesser, Heidi J, Snell, Laura M, Dickson, Russell J, Guo, Mengdi, Hezaveh, Kebria, Xu, Wenxi, Kothari, Akash, McGaha, Tracy L, Guidos, Cynthia J, Brooks, David G
Published in The Journal of experimental medicine (07.12.2020)
Published in The Journal of experimental medicine (07.12.2020)
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Journal Article
CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection
Snell, Laura M, McPherson, Ann J, Lin, Gloria H Y, Sakaguchi, Shimon, Pandolfi, Pier Paolo, Riccardi, Carlo, Watts, Tania H
Published in The Journal of immunology (1950) (15.12.2010)
Published in The Journal of immunology (1950) (15.12.2010)
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