Search Results - "Smyth, Timothy P" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

In Vitro Activities of Synthetic Host Defense Propeptides Processed by Neutrophil Elastase against Cystic Fibrosis Pathogens

In Vitro Activities of Synthetic Host Defense Propeptides Processed by Neutrophil Elastase against Cystic Fibrosis Pathogens

by DESGRANGES, Stephane, LE PRIEULT, Florie, MCELVANEY, Noel G, SMYTH, Timothy P, FITZGERALD-HUGHES, Deirdre, HUMPHREYS, Hilary, DEVOCELLE, Marc, DALY, Alan, LYDON, Jennifer, BRENNAN, Marian, RAI, Dilip K, SUBASINGHAGE, Anusha P, HEWAGE, Chandralal M, CRYAN, Sally-Ann, GREENE, Catherine
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)

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Toward a Clean Alternative to Friedel−Crafts Acylation: In Situ Formation, Observation, and Reaction of an Acyl Bis(trifluoroacetyl)phosphate and Related Structures

Toward a Clean Alternative to Friedel−Crafts Acylation: In Situ Formation, Observation, and Reaction of an Acyl Bis(trifluoroacetyl)phosphate and Related Structures

by Smyth, Timothy P, Corby, Brian W
Published in Journal of organic chemistry (27.11.1998)

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A substrate variant as a high-affinity, reversible inhibitor: insight from the X-ray structure of cilastatin bound to membrane dipeptidase

A substrate variant as a high-affinity, reversible inhibitor: insight from the X-ray structure of cilastatin bound to membrane dipeptidase

by Smyth, Timothy P, Wall, J.Gerard, Nitanai, Yasushi
Published in Bioorganic & medicinal chemistry (20.03.2003)

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Exploring the chemistry of penicillin as a beta-lactamase-dependent prodrug

Exploring the chemistry of penicillin as a beta-lactamase-dependent prodrug

by Ruddle, Carol C., Smyth, Timothy P.
Published in Organic & biomolecular chemistry (01.01.2007)

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Substrate variants versus transition state analogues as noncovalent reversible enzyme inhibitors

Substrate variants versus transition state analogues as noncovalent reversible enzyme inhibitors

by Smyth, Timothy P
Published in Bioorganic & medicinal chemistry (01.08.2004)

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Toward the Development of a Cephalosporin-Based Dual-Release Prodrug for Use in ADEPT

Toward the Development of a Cephalosporin-Based Dual-Release Prodrug for Use in ADEPT

by Grant, Jonathan W, Smyth, Timothy P
Published in Journal of organic chemistry (12.11.2004)

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Penicillins as beta-lactamase-dependent prodrugs: enabling role of a vinyl ester exocyclic to the lactam ring

Penicillins as beta-lactamase-dependent prodrugs: enabling role of a vinyl ester exocyclic to the lactam ring

by Ruddle, CC, Smyth, TP
Published in Chemical communications (Cambridge, England) (21.10.2004)

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Clean-Chemistry Synthesis of 2-Tetralones in a Single-Stage Acylation−Cycloalkylation Process

Clean-Chemistry Synthesis of 2-Tetralones in a Single-Stage Acylation−Cycloalkylation Process

by Gray, Anthony D, Smyth, Timothy P
Published in Journal of organic chemistry (19.10.2001)

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Extending the β-Lactamase-Dependent Prodrug Armory: S-Aminosulfeniminocephalosporins as Dual-Release Prodrugs

Extending the β-Lactamase-Dependent Prodrug Armory: S-Aminosulfeniminocephalosporins as Dual-Release Prodrugs

by Smyth, Timothy P, O'Conno, Michael J, O'Donnell, Michael E
Published in Journal of organic chemistry (30.04.1999)

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Industrially Viable Alternative to the Friedel−Crafts Acylation Reaction: Tamoxifen Case Study

Industrially Viable Alternative to the Friedel−Crafts Acylation Reaction: Tamoxifen Case Study

by Smyth, Timothy P, Corby, Brian W
Published in Organic process research & development (01.07.1997)

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S-Aminosulfeniminopenicillins: Multimode β-Lactamase Inhibitors and Template Structures for Penicillin-Based β-Lactamase Substrates as Prodrugs

S-Aminosulfeniminopenicillins: Multimode β-Lactamase Inhibitors and Template Structures for Penicillin-Based β-Lactamase Substrates as Prodrugs

by Smyth, Timothy P, O'Donnell, Michael E, O'Conno, Michael J, St Ledger, James O
Published in Journal of organic chemistry (30.10.1998)

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β-Lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria

β-Lactam-host defence peptide conjugates as antibiotic prodrug candidates targeting resistant bacteria

by Desgranges, Stéphane, Ruddle, Carol C., Burke, Liam P., McFadden, Tara M., O'Brien, John E., Fitzgerald-Hughes, Deirdre, Humphreys, Hilary, Smyth, Timothy P., Devocelle, Marc
Published in RSC advances (01.01.2012)

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Modular synthesis of pyrrolo[2,1-b]thiazoles and related monocyclic pyrrolo structures

Modular synthesis of pyrrolo[2,1-b]thiazoles and related monocyclic pyrrolo structures

by O'Dwyer, Emma E., Mullane, Nessa S., Smyth, Timothy P.
Published in Journal of heterocyclic chemistry (01.03.2011)

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β-Lactamase-Dependent Prodrugs—Recent Developments

β-Lactamase-Dependent Prodrugs—Recent Developments

by Smyth, Timothy P., O'Donnell, Michael E., O'Connor, Michael J., St Ledger, James O.
Published in Tetrahedron (28.07.2000)

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Inexpensive, active KF for nucleophilic aromatic displacement reactions

Inexpensive, active KF for nucleophilic aromatic displacement reactions

by Smyth, Timothy P., Carey, Aedin, Hodnett, B.K.
Published in Tetrahedron (29.05.1995)

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ChemInform Abstract: Modular Synthesis of Pyrrolo[2,1-b]thiazoles and Related Monocyclic Pyrrolo Structures

ChemInform Abstract: Modular Synthesis of Pyrrolo[2,1-b]thiazoles and Related Monocyclic Pyrrolo Structures

by O'Dwyer, Emma E., Mullane, Nessa S., Smyth, Timothy P.
Published in ChemInform (26.07.2011)

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Clean-chemistry sulfonation of aromatics

Clean-chemistry sulfonation of aromatics

by Corby, BW, Gray, AD, Meaney, PJ, Falvey, MJ, Lawrence, GP, Smyth, TP
Published in Journal of chemical research (01.07.2002)

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Clean-Chemistry Sulfonation of Aromatics

Clean-Chemistry Sulfonation of Aromatics

by Corby, Brian W., Gray, Anthony D., Meaney, Padraig J., Falvey, Michael J., Lawrence, Gregory P., Smyth, Timothy P.
Published in ChemInform (07.01.2003)

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