A Dinuclear Ruthenium(II) Complex Excited by Near-Infrared Light through Two-Photon Absorption Induces Phototoxicity Deep within Hypoxic Regions of Melanoma Cancer Spheroids
Raza, Ahtasham, Archer, Stuart A, Fairbanks, Simon D, Smitten, Kirsty L, Botchway, Stanley W, Thomas, James A, MacNeil, Sheila, Haycock, John W
Published in Journal of the American Chemical Society (11.03.2020)
Published in Journal of the American Chemical Society (11.03.2020)
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Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria
Smitten, Kirsty L, Southam, Hannah M, de la Serna, Jorge Bernardino, Gill, Martin R, Jarman, Paul J, Smythe, Carl G. W, Poole, Robert K, Thomas, Jim A
Published in ACS nano (28.05.2019)
Published in ACS nano (28.05.2019)
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Mononuclear ruthenium() theranostic complexes that function as broad-spectrum antimicrobials in therapeutically resistant pathogens through interaction with DNA
Smitten, Kirsty L, Thick, Eleanor J, Southam, Hannah M, Bernardino de la Serna, Jorge, Foster, Simon J, Thomas, Jim A
Published in Chemical science (Cambridge) (30.07.2020)
Published in Chemical science (Cambridge) (30.07.2020)
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Ruthenium based antimicrobial theranostics - using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus
Smitten, Kirsty L, Fairbanks, Simon D, Robertson, Craig C, Bernardino de la Serna, Jorge, Foster, Simon J, Thomas, Jim A
Published in Chemical science (Cambridge) (07.01.2020)
Published in Chemical science (Cambridge) (07.01.2020)
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Phenazine Cations as Anticancer Theranostics
Noakes, Felicity F., Smitten, Kirsty L., Maple, Laura E. C., Bernardino de la Serna, Jorge, Robertson, Craig C., Pritchard, Dylan, Fairbanks, Simon D., Weinstein, Julia A., Smythe, Carl G. W., Thomas, Jim A.
Published in Journal of the American Chemical Society (08.05.2024)
Published in Journal of the American Chemical Society (08.05.2024)
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Transcriptomic Analysis of the Activity and Mechanism of Action of a Ruthenium(II)-Based Antimicrobial That Induces Minimal Evolution of Pathogen Resistance
Varney, Adam M, Smitten, Kirsty L, Thomas, Jim A, McLean, Samantha
Published in ACS pharmacology & translational science (12.02.2021)
Published in ACS pharmacology & translational science (12.02.2021)
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In Vitro and In Vivo Studies on a Mononuclear Ruthenium Complex Reveals It is a Highly Effective, Fast-Acting, Broad-Spectrum Antimicrobial in Physiologically Relevant Conditions
Varney, Adam M., Smitten, Kirsty L., Southam, Hannah M., Fairbanks, Simon D., Robertson, Craig C., Thomas, Jim A., McLean, Samantha
Published in ACS infectious diseases (13.09.2024)
Published in ACS infectious diseases (13.09.2024)
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Ruthenium based antimicrobial theranostics - using nanoscopy to identify therapeutic targets and resistance mechanisms in
Smitten, Kirsty L, Fairbanks, Simon D, Robertson, Craig C, Bernardino de la Serna, Jorge, Foster, Simon J, Thomas, Jim A
Published in Chemical science (Cambridge) (18.12.2019)
Published in Chemical science (Cambridge) (18.12.2019)
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Ruthenium based antimicrobial theranostics – using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus† †Electronic supplementary information (ESI) available. CCDC 1952088. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c9sc04710g
Smitten, Kirsty L., Fairbanks, Simon D., Robertson, Craig C., Bernardino de la Serna, Jorge, Foster, Simon J., Thomas, Jim A.
Published in Chemical science (Cambridge) (29.10.2019)
Published in Chemical science (Cambridge) (29.10.2019)
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