Restriction of intestinal stem cell expansion and the regenerative response by YAP
Barry, Evan R., Morikawa, Teppei, Butler, Brian L., Shrestha, Kriti, de la Rosa, Rosemarie, Yan, Kelley S., Fuchs, Charles S., Magness, Scott T., Smits, Ron, Ogino, Shuji, Kuo, Calvin J., Camargo, Fernando D.
Published in Nature (London) (03.01.2013)
Published in Nature (London) (03.01.2013)
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Journal Article
Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization
Formentini, Laura, Santacatterina, Fulvio, Núñez de Arenas, Cristina, Stamatakis, Konstantinos, López-Martínez, David, Logan, Angela, Fresno, Manuel, Smits, Ron, Murphy, Michael P., Cuezva, José M.
Published in Cell reports (Cambridge) (09.05.2017)
Published in Cell reports (Cambridge) (09.05.2017)
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Journal Article
The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition
Yu, Jia, Yusoff, Permeen A Mohamed, Woutersen, Daniëlle T J, Goh, Pamela, Harmston, Nathan, Smits, Ron, Epstein, David M, Virshup, David M, Madan, Babita
Published in Cancer research (Chicago, Ill.) (15.12.2020)
Published in Cancer research (Chicago, Ill.) (15.12.2020)
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Journal Article
LGR5 marks targetable tumor-initiating cells in mouse liver cancer
Cao, Wanlu, Li, Meng, Liu, Jiaye, Zhang, Shaoshi, Noordam, Lisanne, Verstegen, Monique M. A., Wang, Ling, Ma, Buyun, Li, Shan, Wang, Wenshi, Bolkestein, Michiel, Doukas, Michael, Chen, Kan, Ma, Zhongren, Bruno, Marco, Sprengers, Dave, Kwekkeboom, Jaap, van der Laan, Luc J. W., Smits, Ron, Peppelenbosch, Maikel P., Pan, Qiuwei
Published in Nature communications (23.04.2020)
Published in Nature communications (23.04.2020)
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Journal Article
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD
Baarsma, Hoeke A, Skronska-Wasek, Wioletta, Mutze, Kathrin, Ciolek, Florian, Wagner, Darcy E, John-Schuster, Gerrit, Heinzelmann, Katharina, Günther, Andreas, Bracke, Ken R, Dagouassat, Maylis, Boczkowski, Jorge, Brusselle, Guy G, Smits, Ron, Eickelberg, Oliver, Yildirim, Ali Ö, Königshoff, Melanie
Published in The Journal of experimental medicine (01.01.2017)
Published in The Journal of experimental medicine (01.01.2017)
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Journal Article
Issues with RNF43 antibodies to reliably detect intracellular location
Li, Shanshan, Zhang, Ruyi, Lavrijsen, Marla, van den Bosch, Thierry P P, Peppelenbosch, Maikel P, Smits, Ron
Published in PloS one (06.04.2023)
Published in PloS one (06.04.2023)
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Journal Article
Human branching cholangiocyte organoids recapitulate functional bile duct formation
Roos, Floris J.M., van Tienderen, Gilles S., Wu, Haoyu, Bordeu, Ignacio, Vinke, Dina, Albarinos, Laura Muñoz, Monfils, Kathryn, Niesten, Sabrah, Smits, Ron, Willemse, Jorke, Rosmark, Oskar, Westergren-Thorsson, Gunilla, Kunz, Daniel J., de Wit, Maurice, French, Pim J., Vallier, Ludovic, IJzermans, Jan N.M., Bartfai, Richard, Marks, Hendrik, Simons, Ben D., van Royen, Martin E., Verstegen, Monique M.A., van der Laan, Luc J.W.
Published in Cell stem cell (05.05.2022)
Published in Cell stem cell (05.05.2022)
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Journal Article
Modeling liver cancer and therapy responsiveness using organoids derived from primary mouse liver tumors
Cao, Wanlu, Liu, Jiaye, Wang, Ling, Li, Meng, Verstegen, Monique M A, Yin, Yuebang, Ma, Buyun, Chen, Kan, Bolkestein, Michiel, Sprengers, Dave, van der Laan, Luc J W, Doukas, Michael, Kwekkeboom, Jaap, Smits, Ron, Peppelenbosch, Maikel P, Pan, Qiuwei
Published in Carcinogenesis (New York) (12.03.2019)
Published in Carcinogenesis (New York) (12.03.2019)
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Journal Article
Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury
Cao, Wanlu, Chen, Kan, Bolkestein, Michiel, Yin, Yuebang, Verstegen, Monique M.A., Bijvelds, Marcel J.C., Wang, Wenshi, Tuysuz, Nesrin, ten Berge, Derk, Sprengers, Dave, Metselaar, Herold J., van der Laan, Luc J.W., Kwekkeboom, Jaap, Smits, Ron, Peppelenbosch, Maikel P., Pan, Qiuwei
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2017)
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Journal Article
Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines
Wang, Wenhui, Liu, Pengyu, Lavrijsen, Marla, Li, Shan, Zhang, Ruyi, Li, Shanshan, van de Geer, Wesley S., van de Werken, Harmen J. G., Peppelenbosch, Maikel P., Smits, Ron
Published in Scientific reports (02.04.2021)
Published in Scientific reports (02.04.2021)
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Journal Article
APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression
Janssen, Klaus-Peter, Alberici, Paola, Fsihi, Hafida, Gaspar, Claudia, Breukel, Cor, Franken, Patrick, Rosty, Christophe, Abal, Miguel, El Marjou, Fatima, Smits, Ron, Louvard, Daniel, Fodde, Riccardo, Robine, Sylvie
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2006)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2006)
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Journal Article
HOXA13 in etiology and oncogenic potential of Barrett’s esophagus
Janmaat, Vincent T., Nesteruk, Kateryna, Spaander, Manon C. W., Verhaar, Auke P., Yu, Bingting, Silva, Rodrigo A., Phillips, Wayne A., Magierowski, Marcin, van de Winkel, Anouk, Stadler, H. Scott, Sandoval-Guzmán, Tatiana, van der Laan, Luc J. W., Kuipers, Ernst J., Smits, Ron, Bruno, Marco J., Fuhler, Gwenny M., Clemons, Nicholas J., Peppelenbosch, Maikel P.
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Journal Article
Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron
Lindström, Nils O, Lawrence, Melanie L, Burn, Sally F, Johansson, Jeanette A, Bakker, Elvira R M, Ridgway, Rachel A, Chang, C-Hong, Karolak, Michele J, Oxburgh, Leif, Headon, Denis J, Sansom, Owen J, Smits, Ron, Davies, Jamie A, Hohenstein, Peter
Published in eLife (03.02.2015)
Published in eLife (03.02.2015)
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Journal Article
Role of CLASP2 in Microtubule Stabilization and the Regulation of Persistent Motility
Drabek, Ksenija, van Ham, Marco, Stepanova, Tatiana, Draegestein, Katharina, van Horssen, Remco, Sayas, Carmen Laura, Akhmanova, Anna, ten Hagen, Timo, Smits, Ron, Fodde, Riccardo, Grosveld, Frank, Galjart, Niels
Published in Current biology (21.11.2006)
Published in Current biology (21.11.2006)
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Journal Article
Sox2 regulates the emergence of lung basal cells by directly activating the transcription of Trp63
Ochieng, Joshua K, Schilders, Kim, Kool, Heleen, Boerema-De Munck, Anne, Buscop-Van Kempen, Marjon, Gontan, Cristina, Smits, Ron, Grosveld, Frank G, Wijnen, Rene M H, Tibboel, Dick, Rottier, Robbert J
Published in American journal of respiratory cell and molecular biology (01.08.2014)
Published in American journal of respiratory cell and molecular biology (01.08.2014)
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Journal Article
A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis
Gaspar, Claudia, Franken, Patrick, Molenaar, Lia, Breukel, Cor, van der Valk, Martin, Smits, Ron, Fodde, Riccardo
Published in PLoS genetics (01.07.2009)
Published in PLoS genetics (01.07.2009)
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