A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1
Botello-Smith, Wesley M, Jiang, Wenjuan, Zhang, Han, Ozkan, Alper D, Lin, Yi-Chun, Pham, Christine N, Lacroix, Jérôme J, Luo, Yun
Published in Nature communications (03.10.2019)
Published in Nature communications (03.10.2019)
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Journal Article
Efficacy of therapeutic plasma exchange in the treatment of penn class 3 and 4 cytokine release syndrome complicating COVID-19
Gluck, W. Larry, Callahan, Sean P., Brevetta, Robert A., Stenbit, Antine E., Smith, Wesley M., Martin, Julie C., Blenda, Anna V., Arce, Sergio, Edenfield, W. Jeffery
Published in Respiratory medicine (01.12.2020)
Published in Respiratory medicine (01.12.2020)
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Journal Article
Molecular Mechanism of Resveratrol's Lipid Membrane Protection
Fei, Qinqin, Kent, David, Botello-Smith, Wesley M, Nur, Fariah, Nur, Saadia, Alsamarah, Abdelaziz, Chatterjee, Payal, Lambros, Maria, Luo, Yun
Published in Scientific reports (25.01.2018)
Published in Scientific reports (25.01.2018)
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Journal Article
Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1
Lacroix, Jerome J, Botello-Smith, Wesley M, Luo, Yun
Published in Nature communications (23.05.2018)
Published in Nature communications (23.05.2018)
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Journal Article
In silico prediction of ARB resistance: A first step in creating personalized ARB therapy
Anderson, Shane D, Tabassum, Asna, Yeon, Jae Kyung, Sharma, Garima, Santos, Priscilla, Soong, Tik Hang, Thu, Yin Win, Nies, Isaac, Kurita, Tomomi, Chandler, Andrew, Alsamarah, Abdelaziz, Kanassatega, Rhye-Samuel, Luo, Yun L, Botello-Smith, Wesley M, Andresen, Bradley T
Published in PLoS computational biology (25.11.2020)
Published in PLoS computational biology (25.11.2020)
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Journal Article
Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock
Botello-Smith, Wesley M, Alsamarah, Abdelaziz, Chatterjee, Payal, Xie, Chen, Lacroix, Jerome J, Hao, Jijun, Luo, Yun
Published in PLoS computational biology (01.08.2017)
Published in PLoS computational biology (01.08.2017)
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Journal Article
Robust Determination of Protein Allosteric Signaling Pathways
Botello-Smith, Wesley M, Luo, Yun
Published in Journal of chemical theory and computation (09.04.2019)
Published in Journal of chemical theory and computation (09.04.2019)
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Journal Article
Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs
Walther, Frans J, Waring, Alan J, Hernandez-Juviel, Jose M, Gordon, Larry M, Wang, Zhengdong, Jung, Chun-Ling, Ruchala, Piotr, Clark, Andrew P, Smith, Wesley M, Sharma, Shantanu, Notter, Robert H
Published in PloS one (13.01.2010)
Published in PloS one (13.01.2010)
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Journal Article
Can Relative Binding Free Energy Predict Selectivity of Reversible Covalent Inhibitors?
Chatterjee, Payal, Botello-Smith, Wesley M, Zhang, Han, Qian, Li, Alsamarah, Abdelaziz, Kent, David, Lacroix, Jerome J, Baudry, Michel, Luo, Yun
Published in Journal of the American Chemical Society (13.12.2017)
Published in Journal of the American Chemical Society (13.12.2017)
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Journal Article
Ion Pairing and Dielectric Decrement in Glycosaminoglycan Brushes
Sterling, James D, Jiang, Wenjuan, Botello-Smith, Wesley M, Luo, Yun L
Published in The journal of physical chemistry. B (18.03.2021)
Published in The journal of physical chemistry. B (18.03.2021)
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Journal Article
Acceleration of Linear Finite-Difference Poisson–Boltzmann Methods on Graphics Processing Units
Qi, Ruxi, Botello-Smith, Wesley M, Luo, Ray
Published in Journal of chemical theory and computation (11.07.2017)
Published in Journal of chemical theory and computation (11.07.2017)
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Journal Article
Numerical Poisson–Boltzmann model for continuum membrane systems
Botello-Smith, Wesley M., Liu, Xingping, Cai, Qin, Li, Zhilin, Zhao, Hongkai, Luo, Ray
Published in Chemical physics letters (03.01.2013)
Published in Chemical physics letters (03.01.2013)
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Journal Article
The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening
Valdez Capuccino, Juan M, Chatterjee, Payal, García, Isaac E, Botello-Smith, Wesley M, Zhang, Han, Harris, Andrew L, Luo, Yun, Contreras, Jorge E
Published in The Journal of general physiology (04.03.2019)
Published in The Journal of general physiology (04.03.2019)
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Journal Article
Alterations at Arg 76 of human connexin 46, a residue associated with cataract formation, cause loss of gap junction formation but preserve hemichannel function
Abrams, Charles K, Peinado, Alejandro, Mahmoud, Rola, Bocarsly, Matan, Zhang, Han, Chang, Paul, Botello-Smith, Wesley M, Freidin, Mona M, Luo, Yun
Published in American Journal of Physiology: Cell Physiology (01.11.2018)
Published in American Journal of Physiology: Cell Physiology (01.11.2018)
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Journal Article
Computer simulations of Piezo1 channel regulation by membrane and small molecule
Lyna Luo, Yun, Jiang, Wenjuan, Lin, YiChun, Zhang, Han, Botello-Smith, Wesley M.
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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