Photoactivatable metal complexes: from theory to applications in biotechnology and medicine
Smith, Nichola A., Sadler, Peter J.
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (28.07.2013)
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (28.07.2013)
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Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity
Smith, Nichola A, Zhang, Pingyu, Greenough, Simon E, Horbury, Michael D, Clarkson, Guy J, McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G, Dowson, Christopher G, Sadler, Peter J
Published in Chemical science (Cambridge) (01.01.2017)
Published in Chemical science (Cambridge) (01.01.2017)
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In Vivo Selectivity and Localization of Reactive Oxygen Species (ROS) Induction by Osmium Anticancer Complexes That Circumvent Platinum Resistance
Coverdale, James P. C, Bridgewater, Hannah E, Song, Ji-Inn, Smith, Nichola A, Barry, Nicolas P. E, Bagley, Ian, Sadler, Peter J, Romero-Canelón, Isolda
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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Ultrafast photo-induced ligand solvolysis of cis-[Ru(bipyridine)2(nicotinamide)2](2+): experimental and theoretical insight into its photoactivation mechanism
Greenough, Simon E, Roberts, Gareth M, Smith, Nichola A, Horbury, Michael D, McKinlay, Russell G, Żurek, Justyna M, Paterson, Martin J, Sadler, Peter J, Stavros, Vasilios G
Published in Physical chemistry chemical physics : PCCP (28.09.2014)
Published in Physical chemistry chemical physics : PCCP (28.09.2014)
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Excited-State Dynamics of a Two-Photon-Activatable Ruthenium Prodrug
Greenough, Simon E., Horbury, Michael D., Smith, Nichola A., Sadler, Peter J., Paterson, Martin J., Stavros, Vasilios G.
Published in Chemphyschem (18.01.2016)
Published in Chemphyschem (18.01.2016)
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Journal Article
Ultrafast photo-induced ligand solvolysis of cis-[Ru(bipyridine) 2 (nicotinamide) 2 ] 2+ : experimental and theoretical insight into its photoactivation mechanism
Greenough, Simon E., Roberts, Gareth M., Smith, Nichola A., Horbury, Michael D., McKinlay, Russell G., Żurek, Justyna M., Paterson, Martin J., Sadler, Peter J., Stavros, Vasilios G.
Published in Physical chemistry chemical physics : PCCP (2014)
Published in Physical chemistry chemical physics : PCCP (2014)
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Journal Article
Introduction: Photoactivatable metal complexes: from theory to applications in biotechnology and medicine
Smith, Nichola A., Sadler, Peter J.
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (28.07.2013)
Get full text
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (28.07.2013)
Journal Article
Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activityElectronic supplementary information (ESI) available: Experimental details include materials, instrumentation, synthesis and characterization, photoactivity against bacteria, transient electronic absorption spectroscopy and computational analysis. Table S1-S5 show the data of X-ray structures and DFT analysis, Fig. S1-S12 give X-ray crystal structures and dark stability of the comp
Smith, Nichola A, Zhang, Pingyu, Greenough, Simon E, Horbury, Michael D, Clarkson, Guy J, McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G, Dowson, Christopher G, Sadler, Peter J
Year of Publication 19.12.2016
Year of Publication 19.12.2016
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Journal Article
Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity† †Electronic supplementary information (ESI) available: Experimental details include materials, instrumentation, synthesis and characterization, photoactivity against bacteria, transient electronic absorption spectroscopy and computational analysis. Table S1–S5 show the data of X-ray structures and DFT analysis, Fig. S1–S12 give X-ray crystal structures and dark stability of the c
Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G., Sadler, Peter J.
Published in Chemical science (Cambridge) (30.08.2016)
Published in Chemical science (Cambridge) (30.08.2016)
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Journal Article
Ultrafast photo-induced ligand solvolysis of cis-[Ru(bipyridine)2(nicotinamide)2]2+: experimental and theoretical insight into its photoactivation mechanismElectronic supplementary information (ESI) available: Electrospray ionization mass spectrum, calculated molecular orbitals for the [Ru(bpy)2(NA)(H2O)]2+ photoproduct, ultrafast and static transient UV/Vis absorption spectra of [Ru(bpy)2(NA)2]2+ in acetone, further kinetic analysis details and enlarged figures of complex structures. See DOI: 1
Greenough, Simon E, Roberts, Gareth M, Smith, Nichola A, Horbury, Michael D, McKinlay, Russell G, urek, Justyna M, Paterson, Martin J, Sadler, Peter J, Stavros, Vasilios G
Year of Publication 20.08.2014
Year of Publication 20.08.2014
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Ultrafast photo-induced ligand solvolysis of cis-[Ru(bipyridine) sub(2)(nicoti namide) sub(2)] super(2+): experimental and theoretical insight into its photoactivation mechanism
Greenough, Simon E, Roberts, Gareth M, Smith, Nichola A, Horbury, Michael D, McKinlay, Russell G, Zurek, Justyna M, Paterson, Martin J, Sadler, Peter J, Stavros, Vasilios G
Published in Physical chemistry chemical physics : PCCP (01.08.2014)
Published in Physical chemistry chemical physics : PCCP (01.08.2014)
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SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE
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Year of Publication 21.01.2022
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Year of Publication 21.01.2022
Patent
NLRP3 INFLAMMASOME INHIBITORS
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Year of Publication 10.12.2021
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Year of Publication 10.12.2021
Patent
Substituted 1,3-phenyl heteroaryl derivatives and their use in the treatment of disease
AXFORD, JAKE, STANLEY, EMILY, SOLOVAY, CATHERINE FOOKS, ADCOCK, CLAIRE, HOU, YING, SUNG, MOO JE, MAZZACANI, ALESSANDRO, SMITH, NICHOLA, WHITEHEAD, LEWIS, SHEN, YI-PING, KIM, HYUNGUL, LIGHTFOOT, MEGAN
Year of Publication 16.06.2021
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Year of Publication 16.06.2021
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NLRP3 inflammasome inhibitors
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Year of Publication 16.03.2021
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Year of Publication 16.03.2021
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PYRAZINE DERIVATIVES AS ENAC BLOCKERS
SMITH NICHOLA, EDWARDS LEE, HUNT PETER, BHALAY GURDIP, HOWSHAM CATHERINE
Year of Publication 30.03.2016
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Year of Publication 30.03.2016
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Pyrazine derivatives as enac blockers
HOWSHAM, CATHERINE, HUNT, PETER, EDWARDS, LEE, SMITH, NICHOLA, BHALAY, GURDIP
Year of Publication 01.03.2016
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Year of Publication 01.03.2016
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Carboxamide derivatives
WRIGGLESWORTH, JOE, TAYLOR, JESSICA LOUISE, TROXLER, THOMAS JOSEF, EDWARDS, ANNE-MARIE, PORTER, DAVID, BALA, KAMLESH JAGDIS, PULZ, ROBERT ALEXANDER, TAYLOR, ROGER JOHN, SANDHAM, DAVID ANDREW, AHMED, MAHBUB, SHAW, DUNCAN, SMITH, NICHOLA, BREARLEY, ANDREW, ROONEY, LISA ANN, DALE, JAMES
Year of Publication 01.01.2021
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Year of Publication 01.01.2021
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