Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat
Park, Thomas J., Reznick, Jane, Peterson, Bethany L., Blass, Gregory, Omerbašić, Damir, Bennett, Nigel C., Kuich, P. Henning J. L., Zasada, Christin, Browe, Brigitte M., Hamann, Wiebke, Applegate, Daniel T., Radke, Michael H., Kosten, Tetiana, Lutermann, Heike, Gavaghan, Victoria, Eigenbrod, Ole, Bégay, Valérie, Amoroso, Vince G., Govind, Vidya, Minshall, Richard D., St. J. Smith, Ewan, Larson, John, Gotthardt, Michael, Kempa, Stefan, Lewin, Gary R.
Published in Science (American Association for the Advancement of Science) (21.04.2017)
Published in Science (American Association for the Advancement of Science) (21.04.2017)
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Journal Article
Regulation of miRNA strand selection: follow the leader?
Meijer, Hedda A, Smith, Ewan M, Bushell, Martin
Published in Biochemical Society transactions (01.08.2014)
Published in Biochemical Society transactions (01.08.2014)
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Journal Article
Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits
Parey, Elise, Fernandez-Aroca, Diego, Frost, Stephanie, Uribarren, Ainhoa, Park, Thomas J., Zöttl, Markus, St. John Smith, Ewan, Berthelot, Camille, Villar, Diego
Published in Genome research (01.09.2023)
Published in Genome research (01.09.2023)
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Journal Article
Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber)
Park, Thomas J, Lu, Ying, Jüttner, René, Smith, Ewan St J, Hu, Jing, Brand, Antje, Wetzel, Christiane, Milenkovic, Nevena, Erdmann, Bettina, Heppenstall, Paul A, Laurito, Charles E, Wilson, Steven P, Lewin, Gary R
Published in PLoS biology (01.01.2008)
Published in PLoS biology (01.01.2008)
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Journal Article
Single-cell RNAseq reveals seven classes of colonic sensory neuron
Hockley, James R F, Taylor, Toni S, Callejo, Gerard, Wilbrey, Anna L, Gutteridge, Alex, Bach, Karsten, Winchester, Wendy J, Bulmer, David C, McMurray, Gordon, Smith, Ewan St John
Published in Gut (01.04.2019)
Published in Gut (01.04.2019)
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Journal Article
A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons
Perez-Sanchez, Jimena, Middleton, Steven J, Pattison, Luke A, Hilton, Helen, Ali Awadelkareem, Mosab, Zuberi, Sana R, Renke, Maria B, Hu, Huimin, Yang, Xun, Clark, Alex J, St John Smith, Ewan, Bennett, David L
Published in Science translational medicine (04.10.2023)
Published in Science translational medicine (04.10.2023)
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Journal Article
Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair
Lu, Wei-Ting, Hawley, Ben R, Skalka, George L, Baldock, Robert A, Smith, Ewan M, Bader, Aldo S, Malewicz, Michal, Watts, Felicity Z, Wilczynska, Ania, Bushell, Martin
Published in Nature communications (07.02.2018)
Published in Nature communications (07.02.2018)
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Journal Article
Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes
Fatima, Iqra, Chen, Guodong, Botchkareva, Natalia V., Sharov, Andrey A., Thornton, Daniel, Wilkinson, Holly N., Hardman, Matthew J., Grutzkau, Andreas, Pedro de Magalhaes, Joao, Seluanov, Andrei, Smith, Ewan St.J., Gorbunova, Vera, Mardaryev, Andrei N., Faulkes, Chris G., Botchkarev, Vladimir A.
Published in Journal of investigative dermatology (01.11.2022)
Published in Journal of investigative dermatology (01.11.2022)
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Journal Article
The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat
St. John Smith, Ewan, Omerbašić, Damir, Lechner, Stefan G., Anirudhan, Gireesh, Lapatsina, Liudmila, Lewin, Gary R.
Published in Science (American Association for the Advancement of Science) (16.12.2011)
Published in Science (American Association for the Advancement of Science) (16.12.2011)
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Journal Article
Role of Human Mesenchymal Stem Cells and Derived Extracellular Vesicles in Reducing Sensory Neuron Hyperexcitability and Pain Behaviors in Murine Osteoarthritis
Ai, Minji, Hotham, William E., Pattison, Luke A., Ma, Qingxi, Henson, Frances M.D., Smith, Ewan St. John
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2023)
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Journal Article
Intraarticular Adeno‐Associated Virus Serotype AAV‐PHP.S–Mediated Chemogenetic Targeting of Knee‐Innervating Dorsal Root Ganglion Neurons Alleviates Inflammatory Pain in Mice
Chakrabarti, Sampurna, Pattison, Luke A., Doleschall, Balint, Rickman, Rebecca H., Blake, Helen, Callejo, Gerard, Heppenstall, Paul A., Smith, Ewan St. John
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2020)
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Journal Article
A Chemoreceptor That Detects Molecular Carbon Dioxide
Smith, Ewan St.John, Martinez-Velazquez, Luis, Ringstad, Niels
Published in The Journal of biological chemistry (27.12.2013)
Published in The Journal of biological chemistry (27.12.2013)
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Journal Article
Somatic mutation rates scale with lifespan across mammals
Cagan, Alex, Baez-Ortega, Adrian, Brzozowska, Natalia, Abascal, Federico, Coorens, Tim H H, Sanders, Mathijs A, Lawson, Andrew R J, Harvey, Luke M R, Bhosle, Shriram, Jones, David, Alcantara, Raul E, Butler, Timothy M, Hooks, Yvette, Roberts, Kirsty, Anderson, Elizabeth, Lunn, Sharna, Flach, Edmund, Spiro, Simon, Januszczak, Inez, Wrigglesworth, Ethan, Jenkins, Hannah, Dallas, Tilly, Masters, Nic, Perkins, Matthew W, Deaville, Robert, Druce, Megan, Bogeska, Ruzhica, Milsom, Michael D, Neumann, Björn, Gorman, Frank, Constantino-Casas, Fernando, Peachey, Laura, Bochynska, Diana, Smith, Ewan St John, Gerstung, Moritz, Campbell, Peter J, Murchison, Elizabeth P, Stratton, Michael R, Martincorena, Iñigo
Published in Nature (London) (21.04.2022)
Published in Nature (London) (21.04.2022)
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