Born to run: control of transcription elongation by RNA polymerase II
Chen, Fei Xavier, Smith, Edwin R., Shilatifard, Ali
Published in Nature reviews. Molecular cell biology (01.07.2018)
Published in Nature reviews. Molecular cell biology (01.07.2018)
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Journal Article
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
Chen, Fei Xavier, Woodfin, Ashley R., Gardini, Alessandro, Rickels, Ryan A., Marshall, Stacy A., Smith, Edwin R., Shiekhattar, Ramin, Shilatifard, Ali
Published in Cell (27.08.2015)
Published in Cell (27.08.2015)
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Journal Article
AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia
Lin, Chengqi, Smith, Edwin R., Takahashi, Hidehisa, Lai, Ka Chun, Martin-Brown, Skylar, Florens, Laurence, Washburn, Michael P., Conaway, Joan W., Conaway, Ronald C., Shilatifard, Ali
Published in Molecular cell (12.02.2010)
Published in Molecular cell (12.02.2010)
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Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation
Douillet, Delphine, Sze, Christie C., Ryan, Caila, Piunti, Andrea, Shah, Avani P., Ugarenko, Michal, Marshall, Stacy A., Rendleman, Emily J., Zha, Didi, Helmin, Kathryn A., Zhao, Zibo, Cao, Kaixiang, Morgan, Marc A., Singer, Benjamin D., Bartom, Elizabeth T., Smith, Edwin R., Shilatifard, Ali
Published in Nature genetics (01.06.2020)
Published in Nature genetics (01.06.2020)
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Journal Article
Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability
Rickels, Ryan, Herz, Hans-Martin, Sze, Christie C, Cao, Kaixiang, Morgan, Marc A, Collings, Clayton K, Gause, Maria, Takahashi, Yoh-hei, Wang, Lu, Rendleman, Emily J, Marshall, Stacy A, Krueger, Annika, Bartom, Elizabeth T, Piunti, Andrea, Smith, Edwin R, Abshiru, Nebiyu A, Kelleher, Neil L, Dorsett, Dale, Shilatifard, Ali
Published in Nature genetics (01.11.2017)
Published in Nature genetics (01.11.2017)
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Journal Article
Zic2 Is an Enhancer-Binding Factor Required for Embryonic Stem Cell Specification
Luo, Zhuojuan, Gao, Xin, Lin, Chengqi, Smith, Edwin R., Marshall, Stacy A., Swanson, Selene K., Florens, Laurence, Washburn, Michael P., Shilatifard, Ali
Published in Molecular cell (19.02.2015)
Published in Molecular cell (19.02.2015)
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Journal Article
Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
Liang, Kaiwei, Smith, Edwin R., Aoi, Yuki, Stoltz, Kristen L., Katagi, Hiroaki, Woodfin, Ashley R., Rendleman, Emily J., Marshall, Stacy A., Murray, David C., Wang, Lu, Ozark, Patrick A., Mishra, Rama K., Hashizume, Rintaro, Schiltz, Gary E., Shilatifard, Ali
Published in Cell (18.10.2018)
Published in Cell (18.10.2018)
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Journal Article
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy
Wang, Lu, Zhao, Zibo, Ozark, Patrick A., Fantini, Damiano, Marshall, Stacy A., Rendleman, Emily J., Cozzolino, Kira A., Louis, Nundia, He, Xingyao, Morgan, Marc A., Takahashi, Yoh-hei, Collings, Clayton K., Smith, Edwin R., Ntziachristos, Panagiotis, Savas, Jeffrey N., Zou, Lihua, Hashizume, Rintaro, Meeks, Joshua J., Shilatifard, Ali
Published in Nature medicine (01.06.2018)
Published in Nature medicine (01.06.2018)
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Journal Article
Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors
Takahashi, Hidehisa, Parmely, Tari J., Sato, Shigeo, Tomomori-Sato, Chieri, Banks, Charles A.S., Kong, Stephanie E., Szutorisz, Henrietta, Swanson, Selene K., Martin-Brown, Skylar, Washburn, Michael P., Florens, Laurence, Seidel, Chris W., Lin, Chengqi, Smith, Edwin R., Shilatifard, Ali, Conaway, Ronald C., Conaway, Joan W.
Published in Cell (08.07.2011)
Published in Cell (08.07.2011)
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An “EAR” on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure–Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters
Blackwell, Brett R, Ankley, Gerald T, Corsi, Steven R, DeCicco, Laura A, Houck, Keith A, Judson, Richard S, Li, Shibin, Martin, Matthew T, Murphy, Elizabeth, Schroeder, Anthony L, Smith, Edwin R, Swintek, Joe, Villeneuve, Daniel L
Published in Environmental science & technology (01.08.2017)
Published in Environmental science & technology (01.08.2017)
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Journal Article
PAF1 regulation of promoter-proximal pause release via enhancer activation
Chen, Fei Xavier, Xie, Peng, Collings, Clayton K., Cao, Kaixiang, Aoi, Yuki, Marshall, Stacy A., Rendleman, Emily J., Ugarenko, Michal, Ozark, Patrick A., Zhang, Anda, Shiekhattar, Ramin, Smith, Edwin R., Zhang, Michael Q., Shilatifard, Ali
Published in Science (American Association for the Advancement of Science) (22.09.2017)
Published in Science (American Association for the Advancement of Science) (22.09.2017)
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Journal Article
Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II
Wang, Pengfei, Lin, Chengqi, Smith, Edwin R., Guo, Hong, Sanderson, Brian W., Wu, Min, Gogol, Madelaine, Alexander, Tara, Seidel, Christopher, Wiedemann, Leanne M., Ge, Kai, Krumlauf, Robb, Shilatifard, Ali
Published in Molecular and Cellular Biology (01.11.2009)
Published in Molecular and Cellular Biology (01.11.2009)
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Journal Article
The COMPASS Family of H3K4 Methylases in Drosophila
Mohan, Man, Herz, Hans-Martin, Smith, Edwin R., Zhang, Ying, Jackson, Jessica, Washburn, Michael P., Florens, Laurence, Eissenberg, Joel C., Shilatifard, Ali
Published in Molecular and Cellular Biology (01.11.2011)
Published in Molecular and Cellular Biology (01.11.2011)
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Journal Article
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia
Liang, Kaiwei, Volk, Andrew G., Haug, Jeffrey S., Marshall, Stacy A., Woodfin, Ashley R., Bartom, Elizabeth T., Gilmore, Joshua M., Florens, Laurence, Washburn, Michael P., Sullivan, Kelly D., Espinosa, Joaquin M., Cannova, Joseph, Zhang, Jiwang, Smith, Edwin R., Crispino, John D., Shilatifard, Ali
Published in Cell (12.01.2017)
Published in Cell (12.01.2017)
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Journal Article
Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC)
Lin, Chengqi, Garrett, Alexander S, De Kumar, Bony, Smith, Edwin R, Gogol, Madelaine, Seidel, Christopher, Krumlauf, Robb, Shilatifard, Ali
Published in Genes & development (15.07.2011)
Published in Genes & development (15.07.2011)
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Journal Article
The Little Elongation Complex Functions at Initiation and Elongation Phases of snRNA Gene Transcription
Hu, Deqing, Smith, Edwin R., Garruss, Alexander S., Mohaghegh, Nima, Varberg, Joseph M., Lin, Chengqi, Jackson, Jessica, Gao, Xin, Saraf, Anita, Florens, Laurence, Washburn, Michael P., Eissenberg, Joel C., Shilatifard, Ali
Published in Molecular cell (22.08.2013)
Published in Molecular cell (22.08.2013)
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Journal Article
The Little Elongation Complex Regulates Small Nuclear RNA Transcription
Smith, Edwin R., Lin, Chengqi, Garrett, Alexander S., Thornton, Janet, Mohaghegh, Nima, Hu, Deqing, Jackson, Jessica, Saraf, Anita, Swanson, Selene K., Seidel, Christopher, Florens, Laurence, Washburn, Michael P., Eissenberg, Joel C., Shilatifard, Ali
Published in Molecular cell (23.12.2011)
Published in Molecular cell (23.12.2011)
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Journal Article
Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity
Luo, Zhuojuan, Lin, Chengqi, Woodfin, Ashley R, Bartom, Elizabeth T, Gao, Xin, Smith, Edwin R, Shilatifard, Ali
Published in Genes & development (01.01.2016)
Published in Genes & development (01.01.2016)
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