Directed evolution to re-adapt a co-evolved network within an enzyme
Strafford, John, Payongsri, Panwajee, Hibbert, Edward G., Morris, Phattaraporn, Batth, Sukhjeet S., Steadman, David, Smith, Mark E.B., Ward, John M., Hailes, Helen C., Dalby, Paul A.
Published in Journal of biotechnology (01.01.2012)
Published in Journal of biotechnology (01.01.2012)
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Directed evolution of transketolase activity on non-phosphorylated substrates
Hibbert, Edward G., Senussi, Tarik, Costelloe, Sean J., Lei, Wenling, Smith, Mark E.B., Ward, John M., Hailes, Helen C., Dalby, Paul A.
Published in Journal of biotechnology (30.09.2007)
Published in Journal of biotechnology (30.09.2007)
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Journal Article
novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells
Ho, Ka-Kei, Rosivatz, Evelyn, Gunn, Richard M, Smith, Mark E.B, Stavropoulou, Alexandra V, Rosivatz, Erika, Numbere, Macba G, Wong, John B, Lafitte, Valerie G.H, Behrendt, Jonathan M, Myatt, Stephen S, Hailes, Helen C, Woscholski, Rüdiger, Lam, Eric W.-F
Published in The FEBS journal (01.08.2009)
Published in The FEBS journal (01.08.2009)
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Journal Article
In vitro metabolism of ceftiofur in bovine tissues
Olson, S.C., Beconi-Barker, M.G., Smith, E.B., Martin, R.A., Vidmar, T.J., Adams, L.D.
Published in Journal of veterinary pharmacology and therapeutics (01.04.1998)
Published in Journal of veterinary pharmacology and therapeutics (01.04.1998)
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Journal Article
Use of hydrolases for the synthesis of cyclic amino acids
Lloyd, Richard C, Lloyd, Michael C, Smith, Mark E.B, Holt, Karen E, Swift, Jonathan P, Keene, Philip A, Taylor, Stephen J.C, McCague, Raymond
Published in Tetrahedron (01.01.2004)
Published in Tetrahedron (01.01.2004)
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Journal Article
Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides
Smith, Mark E. B, Schumacher, Felix F, Ryan, Chris P, Tedaldi, Lauren M, Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R
Published in Journal of the American Chemical Society (17.02.2010)
Published in Journal of the American Chemical Society (17.02.2010)
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An integrated modeling approach to simulate human-crop-groundwater interactions in intensively irrigated regions
Nozari, Soheil, Bailey, Ryan T., Rad, Mani Rouhi, Smith, Garvey E.B., Andales, Allan A., Zambreski, Zachary T., Tavakoli-Kivi, Saman, Sharda, Vaishali, Kisekka, Isaya, Gowda, Prasanna, Schipanski, Meagan E.
Published in Environmental modelling & software : with environment data news (01.08.2024)
Published in Environmental modelling & software : with environment data news (01.08.2024)
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Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging
Schumacher, Felix F., Nunes, Joao P. M., Maruani, Antoine, Chudasama, Vijay, Smith, Mark E. B., Chester, Kerry A., Baker, James R., Caddick, Stephen
Published in Organic & biomolecular chemistry (07.10.2014)
Published in Organic & biomolecular chemistry (07.10.2014)
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Journal Article
Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody-drug conjugate (ADC)
Nunes, João P M, Morais, Maurício, Vassileva, Vessela, Robinson, Eifion, Rajkumar, Vineeth S, Smith, Mark E B, Pedley, R Barbara, Caddick, Stephen, Baker, James R, Chudasama, Vijay
Published in Chemical communications (Cambridge, England) (07.07.2015)
Published in Chemical communications (Cambridge, England) (07.07.2015)
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Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis
Morais, Mauricio, Nunes, Joao P. M., Karu, Kersti, Forte, Nafsika, Benni, Irene, Smith, Mark E. B., Caddick, Stephen, Chudasama, Vijay, Baker, James R.
Published in Organic & biomolecular chemistry (05.04.2017)
Published in Organic & biomolecular chemistry (05.04.2017)
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