Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
Sathasivam, Kirupa, Neueder, Andreas, Gipson, Theresa A., Landles, Christian, Benjamin, Agnesska C., Bondulich, Marie K., Smith, Donna L., Faull, Richard L. M., Roos, Raymund A. C., Howland, David, Detloff, Peter J., Housman, David E., Bates, Gillian P.
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2013)
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HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration
Mielcarek, Michal, Landles, Christian, Weiss, Andreas, Bradaia, Amyaouch, Seredenina, Tamara, Inuabasi, Linda, Osborne, Georgina F, Wadel, Kristian, Touller, Chrystelle, Butler, Rachel, Robertson, Janette, Franklin, Sophie A, Smith, Donna L, Park, Larry, Marks, Paul A, Wanker, Erich E, Olson, Eric N, Luthi-Carter, Ruth, van der Putten, Herman, Beaumont, Vahri, Bates, Gillian P
Published in PLoS biology (01.11.2013)
Published in PLoS biology (01.11.2013)
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SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease
Mielcarek, Michal, Benn, Caroline L, Franklin, Sophie A, Smith, Donna L, Woodman, Ben, Marks, Paul A, Bates, Gillian P
Published in PloS one (28.11.2011)
Published in PloS one (28.11.2011)
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Dysfunction of the CNS-heart axis in mouse models of Huntington's disease
Mielcarek, Michal, Inuabasi, Linda, Bondulich, Marie K, Muller, Thomas, Osborne, Georgina F, Franklin, Sophie A, Smith, Donna L, Neueder, Andreas, Rosinski, Jim, Rattray, Ivan, Protti, Andrea, Bates, Gillian P
Published in PLoS genetics (01.08.2014)
Published in PLoS genetics (01.08.2014)
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SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
Luthi-Carter, Ruth, Taylor, David M, Pallos, Judit, Lambert, Emmanuel, Amore, Allison, Parker, Alex, Moffitt, Hilary, Smith, Donna L, Runne, Heike, Gokce, Ozgun, Kuhn, Alexandre, Xiang, Zhongmin, Maxwell, Michele M, Reeves, Steven A, Bates, Gillian P, Neri, Christian, Thompson, Leslie M, Marsh, J. Lawrence, Kazantsev, Aleksey G
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
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Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell‐type‐specific
Jansen, Anne H.P., van Hal, Maurik, op den Kelder, Ilse C., Meier, Romy T., de Ruiter, Anna‐Aster, Schut, Menno H., Smith, Donna L., Grit, Corien, Brouwer, Nieske, Kamphuis, Willem, Boddeke, H.W.G.M., den Dunnen, Wilfred F.A., van Roon, Willeke M.C., Bates, Gillian P., Hol, Elly M., Reits, Eric A.
Published in Glia (01.01.2017)
Published in Glia (01.01.2017)
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SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice
Tulino, Raffaella, Benjamin, Agnesska C, Jolinon, Nelly, Smith, Donna L, Chini, Eduardo N, Carnemolla, Alisia, Bates, Gillian P
Published in PloS one (27.01.2016)
Published in PloS one (27.01.2016)
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Characterisation of immune cell function in fragment and full-length Huntington's disease mouse models
Träger, Ulrike, Andre, Ralph, Magnusson-Lind, Anna, Miller, James R.C, Connolly, Colúm, Weiss, Andreas, Grueninger, Stephan, Silajdžić, Edina, Smith, Donna L, Leavitt, Blair R, Bates, Gillian P, Björkqvist, Maria, Tabrizi, Sarah J
Published in Neurobiology of disease (01.01.2015)
Published in Neurobiology of disease (01.01.2015)
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A Potent Small Molecule Inhibits Polyglutamine Aggregation in Huntington's Disease Neurons and Suppresses Neurodegeneration in vivo
Zhang, Xiaoqian, Smith, Donna L., Meriin, Anatoli B., Engemann, Sabine, Russel, Deborah E., Roark, Margo, Washington, Shetia L., Maxwell, Michele M., Marsh, J. Lawrence, Thompson, Leslie Michels, Wanker, Erich E., Young, Anne B., Housman, David E., Bates, Gillian P., Sherman, Michael Y., Kazantsev, Aleksey G.
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2005)
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Journal Article
Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington’s disease mice
Bondulich, Marie K., Jolinon, Nelly, Osborne, Georgina F., Smith, Edward J., Rattray, Ivan, Neueder, Andreas, Sathasivam, Kirupa, Ahmed, Mhoriam, Ali, Nadira, Benjamin, Agnesska C., Chang, Xiaoli, Dick, James R. T., Ellis, Matthew, Franklin, Sophie A., Goodwin, Daniel, Inuabasi, Linda, Lazell, Hayley, Lehar, Adam, Richard-Londt, Angela, Rosinski, Jim, Smith, Donna L., Wood, Tobias, Tabrizi, Sarah J., Brandner, Sebastian, Greensmith, Linda, Howland, David, Munoz-Sanjuan, Ignacio, Lee, Se-Jin, Bates, Gillian P.
Published in Scientific reports (27.10.2017)
Published in Scientific reports (27.10.2017)
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Suberoylanilide Hydroxamic Acid, a Histone Deacetylase Inhibitor, Ameliorates Motor Deficits in a Mouse Model of Huntington's Disease
Hockly, Emma, Richon, Victoria M., Woodman, Benjamin, Smith, Donna L., Zhou, Xianbo, Rosa, Eddie, Sathasivam, Kirupa, Ghazi-Noori, Shabnam, Mahal, Amarbirpal, Philip A. S. Lowden, Steffan, Joan S., Marsh, J. Lawrence, Thompson, Leslie M., Lewis, Cathryn M., Marks, Paul A., Bates, Gillian P.
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2003)
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Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivo
Beconi, Maria, Aziz, Omar, Matthews, Kim, Moumné, Lara, O'Connell, Catherine, Yates, Dawn, Clifton, Steven, Pett, Hannah, Vann, Julie, Crowley, Lynsey, Haughan, Alan F, Smith, Donna L, Woodman, Ben, Bates, Gillian P, Brookfield, Fred, Bürli, Roland W, McAllister, George, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Beaumont, Vahri
Published in PloS one (04.09.2012)
Published in PloS one (04.09.2012)
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Journal Article
Correction: SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice
Tulino, Raffaella, Benjamin, Agnesska C, Jolinon, Nelly, Smith, Donna L, Chini, Eduardo N, Carnemolla, Alisia, Bates, Gillian P
Published in PloS one (26.02.2016)
Published in PloS one (26.02.2016)
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A Web-Based, Population-Based Cirrhosis Identification and Management System for Improving Cirrhosis Care: Qualitative Formative Evaluation
Javier, Sarah J, Wu, Justina, Smith, Donna L, Kanwal, Fasiha, Martin, Lindsey A, Clark, Jack, Midboe, Amanda M
Published in JMIR formative research (09.11.2021)
Published in JMIR formative research (09.11.2021)
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Workplace model for physical therapists and occupational therapists
I.J. Wagner, Joan, Warren, Sharon, Cummings, Greta, L. Smith, Donna, K. Olson, Joanne
Published in Journal of health organization and management (01.01.2014)
Published in Journal of health organization and management (01.01.2014)
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Ciprofloxacin-Resistant Gram-Negative Bacilli in the Fecal Microflora of Children
XUAN QIN, RAZIA, Yasmin, TARR, Phillip I, JOHNSON, James R, STAPP, Jennifer R, BOSTER, Daniel R, TSOSIE, Treva, SMITH, Donna L, BRADEN, Christopher R, GAY, Kathryn, ANGULO, Frederick J
Published in Antimicrobial Agents and Chemotherapy (01.10.2006)
Published in Antimicrobial Agents and Chemotherapy (01.10.2006)
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Palladium-catalyzed hydroacyloxylation of ynamides
Smith, Donna L., Goundry, William R. F., Lam, Hon Wai
Published in Chemical communications (Cambridge, England) (01.02.2012)
Published in Chemical communications (Cambridge, England) (01.02.2012)
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Intuitive Global Insight Into COVID-19 Clinical Research Activities-The "COVID-19 Map of Hope"
Ries, Markus, Mechler, Konstantin, Smith, Donna L, Herfort, Benjamin, Visintini, Johannes, Santana, Amon Veiga, Zipf, Alexander, Lautenbach, Sven
Published in Journal of clinical pharmacology (01.07.2020)
Published in Journal of clinical pharmacology (01.07.2020)
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