Characterization of Differential Tissue Abundance of Major Non-CYP Enzymes in Human
Basit, Abdul, Neradugomma, Naveen K, Wolford, Christopher, Fan, Peter W, Murray, Bernard, Takahashi, Ryan H, Khojasteh, S. Cyrus, Smith, Bill J, Heyward, Scott, Totah, Rheem A, Kelly, Edward J, Prasad, Bhagwat
Published in Molecular pharmaceutics (02.11.2020)
Published in Molecular pharmaceutics (02.11.2020)
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Progress in Brain Penetration Evaluation in Drug Discovery and Development
Liu, Xingrong, Chen, Cuiping, Smith, Bill J
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
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Journal Article
Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells
Li, Ruidong, Liclican, Albert, Xu, Yili, Pitts, Jared, Niu, Congrong, Zhang, Jingyu, Kim, Cynthia, Zhao, Xiaofeng, Soohoo, Daniel, Babusis, Darius, Yue, Qin, Ma, Bin, Murray, Bernard P, Subramanian, Raju, Xie, Xuping, Zou, Jing, Bilello, John P, Li, Li, Schultz, Brian E, Sakowicz, Roman, Smith, Bill J, Shi, Pei-Yong, Murakami, Eisuke, Feng, Joy Y
Published in Antimicrobial agents and chemotherapy (17.08.2021)
Published in Antimicrobial agents and chemotherapy (17.08.2021)
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Characterization of Seasonal Pharmacokinetic Variability in Woodchucks
Zheng, Jim, Balsitis, Scott, Santos, Rex, Smith, Bill J, Subramanian, Raju
Published in Drug metabolism and disposition (01.11.2020)
Published in Drug metabolism and disposition (01.11.2020)
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Journal Article
Regional proteomic quantification of clinically relevant non-cytochrome P450 enzymes along the human small intestine
Zhang, Haeyoung, Wolford, Chris, Basit, Abdul, Li, Albert P, Fan, Peter W, Takahashi, Ryan H, Khojasteh, S Cyrus, Smith, Bill J, Murray, Bernard P, Thummel, Kenneth, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.07.2020)
Published in Drug metabolism and disposition (01.07.2020)
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Comparison of Tissue Abundance of Non-Cytochrome P450 Drug-Metabolizing Enzymes by Quantitative Proteomics between Humans and Laboratory Animal Species
Basit, Abdul, Fan, Peter W, Khojasteh, S Cyrus, Murray, Bernard P, Smith, Bill J, Heyward, Scott, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.03.2022)
Published in Drug metabolism and disposition (01.03.2022)
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18O‑Enabled High-Throughput Acyl Glucuronide Stability Assay
Yu, Zaikuan Josh, Le, Hoa, Tang, Jennifer, Yue, Qin, Zhang, Jingyu, Murray, Bernard, Liu, Xingrong, Smith, Bill J., Subramanian, Raju
Published in Chemical research in toxicology (15.08.2022)
Published in Chemical research in toxicology (15.08.2022)
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Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches
Hosea, Natilie A, Collard, Wendy T, Cole, Susan, Maurer, Tristan S, Fang, Rick X, Jones, Hannah, Kakar, Shefali M, Nakai, Yasuhiro, Smith, Bill J, Webster, Rob, Beaumont, Kevin
Published in Journal of clinical pharmacology (01.05.2009)
Published in Journal of clinical pharmacology (01.05.2009)
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Human and nonclinical disposition of [14C]bictegravir, a potent integrase strand-transfer inhibitor for the treatment of HIV-1 infection
Subramanian, Raju, Ling, John, Wang, Jianhong, Wang, Kelly, Hao, Jia, Jin, Haolun, Lai, Yurong, Murray, Bernard, Wijaya, Samantha, Zhang, Heather, Smith, Bill J.
Published in Xenobiotica (02.11.2022)
Published in Xenobiotica (02.11.2022)
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Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent
Subramanian, Raju, Tang, Jennifer, Zheng, Jim, Lu, Bing, Wang, Kelly, Yant, Stephen R, Stepan, George J, Mulato, Andrew, Yu, Helen, Schroeder, Scott, Shaik, Naveed, Singh, Renu, Wolckenhauer, Scott, Chester, Anne, Tse, Winston C, Chiu, Anna, Rhee, Martin, Cihlar, Tomas, Rowe, William, Smith, Bill J
Published in Molecular pharmaceutics (04.12.2023)
Published in Molecular pharmaceutics (04.12.2023)
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Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs
Subash, Sandhya, Singh, Dilip K, Ahire, Deepak S, Khojasteh, S Cyrus, Murray, Bernard P, Zientek, Michael A, Jones, Robert S, Kulkarni, Priyanka, Smith, Bill J, Heyward, Scott, Cronin, Ciarán N, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.10.2023)
Published in Drug metabolism and disposition (01.10.2023)
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Social cognitive determinants of nutrition and physical activity among web-health users enrolling in an online intervention: the influence of social support, self-efficacy, outcome expectations, and self-regulation
Anderson-Bill, Eileen Smith, Winett, Richard A, Wojcik, Janet R
Published in Journal of medical Internet research (17.03.2011)
Published in Journal of medical Internet research (17.03.2011)
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Ontogeny of Human Liver Aldehyde Oxidase: Developmental Changes and Implications for Drug Metabolism
Subash, Sandhya, Singh, Dilip K., Ahire, Deepak, Khojasteh, S. Cyrus, Murray, Bernard P., Zientek, Michael A., Jones, Robert S., Kulkarni, Priyanka, Zubair, Faizan, Smith, Bill J., Heyward, Scott, Leeder, J. Steven, Prasad, Bhagwat
Published in Molecular pharmaceutics (03.06.2024)
Published in Molecular pharmaceutics (03.06.2024)
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Human pharmacokinetics prediction with an in vitro-in vivo correction factor approach and in vitro drug-drug interaction profile of bictegravir, a potent integrase-strand transfer inhibitor component in approved biktarvy® for the treatment of HIV-1 infection
Subramanian, Raju, Wang, Jianhong, Murray, Bernard, Custodio, Joseph, Hao, Jia, Lazerwith, Scott, MacLennan Staiger, Kelly, Mwangi, Judy, Sun, Hailing, Tang, Jennifer, Wang, Kelly, Rhodes, Gerry, Wijaya, Samantha, Zhang, Heather, Smith, Bill J.
Published in Xenobiotica (02.12.2022)
Published in Xenobiotica (02.12.2022)
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Journal Article
Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development
Zheng, Jim, Xin, Yan, Zhang, Jingyu, Subramanian, Raju, Murray, Bernard P, Whitney, J Andrew, Warr, Matthew R, Ling, John, Moorehead, Lisa, Kwan, Ellen, Hemenway, Jeffrey, Smith, Bill J, Silverman, Jeffrey A
Published in Drug metabolism and disposition (01.03.2018)
Published in Drug metabolism and disposition (01.03.2018)
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Journal Article
Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection
Pitts, Jared, Babusis, Darius, Vermillion, Meghan S., Subramanian, Raju, Barrett, Kim, Lye, Diane, Ma, Bin, Zhao, Xiaofeng, Riola, Nicholas, Xie, Xuping, Kajon, Adriana, Lu, Xianghan, Bannister, Roy, Shi, Pei-Yong, Toteva, Maria, Porter, Danielle P., Smith, Bill J., Cihlar, Tomas, Mackman, Richard, Bilello, John P.
Published in Antiviral research (01.07.2022)
Published in Antiviral research (01.07.2022)
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Pharmacokinetic/pharmacodynamic modeling of crizotinib for anaplastic lymphoma kinase inhibition and antitumor efficacy in human tumor xenograft mouse models
Yamazaki, Shinji, Vicini, Paolo, Shen, Zhongzhou, Zou, Helen Y, Lee, Joseph, Li, Qiuhua, Christensen, James G, Smith, Bill J, Shetty, Bhasker
Published in The Journal of pharmacology and experimental therapeutics (01.03.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2012)
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