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Finan, Brian, Yang, Bin, Ottaway, Nickki, Smiley, David L, Ma, Tao, Clemmensen, Christoffer, Chabenne, Joe, Zhang, Lianshan, Habegger, Kirk M, Fischer, Katrin, Campbell, Jonathan E, Sandoval, Darleen, Seeley, Randy J, Bleicher, Konrad, Uhles, Sabine, Riboulet, William, Funk, Jürgen, Hertel, Cornelia, Belli, Sara, Sebokova, Elena, Conde-Knape, Karin, Konkar, Anish, Drucker, Daniel J, Gelfanov, Vasily, Pfluger, Paul T, Müller, Timo D, Perez-Tilve, Diego, DiMarchi, Richard D, Tschöp, Matthias H
Published in Nature medicine (01.01.2015)
Published in Nature medicine (01.01.2015)
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Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors
Heppner, Kristy M, Piechowski, Carolin L, Müller, Anne, Ottaway, Nickki, Sisley, Stephanie, Smiley, David L, Habegger, Kirk M, Pfluger, Paul T, Dimarchi, Richard, Biebermann, Heike, Tschöp, Matthias H, Sandoval, Darleen A, Perez-Tilve, Diego
Published in Diabetes (New York, N.Y.) (01.01.2014)
Published in Diabetes (New York, N.Y.) (01.01.2014)
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Ghrelin-induced adiposity is independent of orexigenic effects
Perez-Tilve, Diego, Heppner, Kristy, Kirchner, Henriette, Lockie, Sarah H, Woods, Stephen C, Smiley, David L, Tschöp, Matthias, Pfluger, Paul
Published in The FASEB journal (01.08.2011)
Published in The FASEB journal (01.08.2011)
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A Novel Human-Based Receptor Antagonist of Sustained Action Reveals Body Weight Control by Endogenous GLP-1
Patterson, James T, Ottaway, Nickki, Gelfanov, Vasily M, Smiley, David L, Perez-Tilve, Diego, Pfluger, Paul T, Tschöp, Matthias H, DiMarchi, Richard D
Published in ACS chemical biology (18.02.2011)
Published in ACS chemical biology (18.02.2011)
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Acylation Type Determines Ghrelin's Effects on Energy Homeostasis in Rodents
Heppner, Kristy M, Chaudhary, Nilika, Müller, Timo D, Kirchner, Henriette, Habegger, Kirk M, Ottaway, Nickki, Smiley, David L, DiMarchi, Richard, Hofmann, Susanna M, Woods, Stephen C, Sivertsen, Bjørn, Holst, Birgitte, Pfluger, Paul T, Perez-Tilve, Diego, Tschöp, Matthias H
Published in Endocrinology (Philadelphia) (01.10.2012)
Published in Endocrinology (Philadelphia) (01.10.2012)
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Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans
Finan, Brian, Ma, Tao, Ottaway, Nickki, Müller, Timo D, Habegger, Kirk M, Heppner, Kristy M, Kirchner, Henriette, Holland, Jenna, Hembree, Jazzminn, Raver, Christine, Lockie, Sarah H, Smiley, David L, Gelfanov, Vasily, Yang, Bin, Hofmann, Susanna, Bruemmer, Dennis, Drucker, Daniel J, Pfluger, Paul T, Perez-Tilve, Diego, Gidda, Jaswant, Vignati, Louis, Zhang, Lianshan, Hauptman, Jonathan B, Lau, Michele, Brecheisen, Mathieu, Uhles, Sabine, Riboulet, William, Hainaut, Emmanuelle, Sebokova, Elena, Conde-Knape, Karin, Konkar, Anish, DiMarchi, Richard D, Tschöp, Matthias H
Published in Science translational medicine (30.10.2013)
Published in Science translational medicine (30.10.2013)
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Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells
Kuna, Ramya S, Girada, Shravan Babu, Asalla, Suman, Vallentyne, Joyprashant, Maddika, Subbareddy, Patterson, James T, Smiley, David L, DiMarchi, Richard D, Mitra, Prasenjit
Published in American journal of physiology: endocrinology and metabolism (15.07.2013)
Published in American journal of physiology: endocrinology and metabolism (15.07.2013)
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Design and synthesis of statine-containing BACE inhibitors
JINGDAN HU, CWI, Cynthia L, MCCARTHY, James R, SMILEY, David L, TIMM, David, ERICKSON, Jon A, MCGEE, James E, YANG, Hsiu-Chiung, MENDEL, David, MAY, Patrick C, SHAPIRO, Mike
Published in Bioorganic & medicinal chemistry letters (15.12.2003)
Published in Bioorganic & medicinal chemistry letters (15.12.2003)
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A new quorum‐sensing system (TprA/PhrA) for Streptococcus pneumoniae D39 that regulates a lantibiotic biosynthesis gene cluster
Hoover, Sharon E., Perez, Amilcar J., Tsui, Ho‐Ching T., Sinha, Dhriti, Smiley, David L., DiMarchi, Richard D., Winkler, Malcolm E., Lazazzera, Beth A.
Published in Molecular microbiology (01.07.2015)
Published in Molecular microbiology (01.07.2015)
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Neuropeptide Y-Y2 receptors mediate anxiety in the amygdala
Sajdyk, Tammy J, Schober, Douglas A, Smiley, David L, Gehlert, Donald R
Published in Pharmacology, biochemistry and behavior (01.03.2002)
Published in Pharmacology, biochemistry and behavior (01.03.2002)
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A Novel and Selective β-Melanocyte-Stimulating Hormone-Derived Peptide Agonist for Melanocortin 4 Receptor Potently Decreased Food Intake and Body Weight Gain in Diet-Induced Obese Rats
Hsiung, Hansen M, Hertel, JeAnne, Zhang, Xing-yue, Smith, Dennis P, Smiley, David L, Heiman, Mark L, Yang, Derek D, Husain, Saba, Mayer, John P, Zhang, Lianshan, Mo, Huaping, Yan, Liang Zeng
Published in Endocrinology (Philadelphia) (01.12.2005)
Published in Endocrinology (Philadelphia) (01.12.2005)
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Discovery of a β-MSH-Derived MC-4R Selective Agonist
Mayer, John P, Hsiung, Hansen M, Flora, David B, Edwards, Patrick, Smith, Dennis P, Zhang, Xing-Yue, Gadski, Robert A, Heiman, Mark L, Hertel, JeAnne L, Emmerson, Paul J, Husain, Saba, O'Brien, Thomas P, Kahl, Steven D, Smiley, David L, Zhang, Lianshan, DiMarchi, Richard D, Yan, Liang Zeng
Published in Journal of medicinal chemistry (05.05.2005)
Published in Journal of medicinal chemistry (05.05.2005)
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Europium-labeled melanin-concentrating hormone analogues: ligands for measuring binding to melanin-concentrating hormone receptors 1 and 2
Gao, Xiaoying, Hsu, Chiun-King, Heinz, Lawrence J, Morin, John, Shi, Yuguang, Shukla, Nikhil K, Smiley, David L, Xu, Jie, Zhong, Boyu, Slieker, Lawrence J
Published in Analytical biochemistry (15.05.2004)
Published in Analytical biochemistry (15.05.2004)
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Potent peptide agonists for human melanocortin 3 and 4 receptors derived from enzymatic cleavages of human β-MSH(5–22) by dipeptidyl peptidase I and dipeptidyl peptidase IV
Hsiung, Hansen M., Smiley, David L., Zhang, Xing-yue, Zhang, Lianshan, Yan, Liang Zeng, Craft, Libbey, Heiman, Mark L., Smith, Dennis P.
Published in Peptides (New York, N.Y. : 1980) (01.10.2005)
Published in Peptides (New York, N.Y. : 1980) (01.10.2005)
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Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold
Yan, Liang Z., Flora, David, Edwards, Patrick, Smiley, David L., Emmerson, Paul J., Hsiung, Hansen M., Gadski, Robert, Hertel, JeAnne, Heiman, Mark L., Husain, Saba, O’Brien, Thomas P., Kahl, Steven D., Zhang, Lianshan, DiMarchi, Richard D., Mayer, John P.
Published in Bioorganic & medicinal chemistry letters (15.10.2005)
Published in Bioorganic & medicinal chemistry letters (15.10.2005)
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GLUCAGON ANALOGS EXHIBITING ENHANCED SOLUBILITY AND STABILITY IN PHYSIOLOGICAL pH BUFFERS
SMILEY DAVID L, DIMARCHI RICHARD D, CHABENNE JOSEPH, DAY JONATHAN, DIMARCHI MARIA
Year of Publication 20.08.2015
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Year of Publication 20.08.2015
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