Structural basis for mouse LAG3 interactions with the MHC class II molecule I-Ab
Ming, Qianqian, Antfolk, Daniel, Price, David A., Manturova, Anna, Medina, Elliot, Singh, Srishti, Mason, Charlotte, Tran, Timothy H., Smalley, Keiran S. M., Leung, Daisy W., Luca, Vincent C.
Published in Nature communications (29.08.2024)
Published in Nature communications (29.08.2024)
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Journal Article
HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis
Emmons, Michael F, Bennett, Richard L, Riva, Alberto, Gupta, Kanchan, Carvalho, Larissa Anastasio Da Costa, Zhang, Chao, Macaulay, Robert, Dupéré-Richér, Daphne, Fang, Bin, Seto, Edward, Koomen, John M, Li, Jiannong, Chen, Y Ann, Forsyth, Peter A, Licht, Jonathan D, Smalley, Keiran S M
Published in Nature communications (29.11.2023)
Published in Nature communications (29.11.2023)
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Journal Article
Metabolomics of primary cutaneous melanoma and matched adjacent extratumoral microenvironment
Taylor, Nicholas J, Gaynanova, Irina, Eschrich, Steven A, Welsh, Eric A, Garrett, Timothy J, Beecher, Chris, Sharma, Ritin, Koomen, John M, Smalley, Keiran S M, Messina, Jane L, Kanetsky, Peter A
Published in PloS one (27.10.2020)
Published in PloS one (27.10.2020)
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Journal Article
Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase with Potent Antimelanoma Activity
Tsai, James, Lee, John T., Wang, Weiru, Zhang, Jiazhong, Cho, Hanna, Mamo, Shumeye, Bremer, Ryan, Gillette, Sam, Kong, Jun, Haass, Nikolas K., Sproesser, Katrin, Li, Ling, Smalley, Keiran S. M., Fong, Daniel, Zhu, Yong-Liang, Marimuthu, Adhirai, Nguyen, Hoa, Lam, Billy, Liu, Jennifer, Cheung, Ivana, Rice, Julie, Suzuki, Yoshihisa, Luu, Catherine, Settachatgul, Calvin, Shellooe, Rafe, Cantwell, John, Kim, Sung-Hou, Schlessinger, Joseph, Zhang, Kam Y. J., West, Brian L., Powell, Ben, Habets, Gaston, Zhang, Chao, Ibrahim, Prabha N., Hirth, Peter, Artis, Dean R., Herlyn, Meenhard, Bollag, Gideon
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
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Journal Article
Fibroblasts Contribute to Melanoma Tumor Growth and Drug Resistance
Flach, Edward H, Rebecca, Vito W, Herlyn, Meenhard, Smalley, Keiran S. M, Anderson, Alexander R. A
Published in Molecular pharmaceutics (05.12.2011)
Published in Molecular pharmaceutics (05.12.2011)
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Journal Article
The anti-melanoma activity of dinaciclib, a cyclin-dependent kinase inhibitor, is dependent on p53 signaling
Desai, Brijal M, Villanueva, Jessie, Nguyen, Thierry-Thien K, Lioni, Mercedes, Xiao, Min, Kong, Jun, Krepler, Clemens, Vultur, Adina, Flaherty, Keith T, Nathanson, Katherine L, Smalley, Keiran S M, Herlyn, Meenhard
Published in PloS one (18.03.2013)
Published in PloS one (18.03.2013)
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Journal Article
LIFE ISN'T FLAT: TAKING CANCER BIOLOGY TO THE NEXT DIMENSION
SMALLEY, KEIRAN S. M, LIONI, MERCEDES, HERLYN, MEENHARD
Published in In vitro cellular & developmental biology. Animal (01.09.2006)
Published in In vitro cellular & developmental biology. Animal (01.09.2006)
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Journal Article
Novel Anti-Melanoma Compounds Are Efficacious in A375 Cell Line Xenograft Melanoma Model in Nude Mice
Velayutham, Sadeeshkumar, Seerattan, Ryan, Sultan, Maab, Seal, Trisha, Danthurthy, Samaya, Chinnappan, Baskaran, Landi, Jessica, Pearl, Kaitlyn, Singh, Aveta, Smalley, Keiran S M, Zaias, Julia, Choi, Jun Yong, Minond, Dmitriy
Published in Biomolecules (Basel, Switzerland) (22.08.2023)
Published in Biomolecules (Basel, Switzerland) (22.08.2023)
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Journal Article
An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells
SMALLEY, Keiran S. M, CONTRACTOR, Rooha, HERLYN, Meenhard, HAASS, Nikolas K, KULP, Angela N, EKIN ATILLA-GOKCUMEN, G, WILLIAMS, Douglas S, BREGMAN, Howard, FLAHERTY, Keith T, SOENGAS, Maria S, MEGGERS, Eric
Published in Cancer research (Chicago, Ill.) (2007)
Published in Cancer research (Chicago, Ill.) (2007)
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Journal Article
Modeling Melanoma Heterogeneity In Vitro: Redox, Resistance and Pigmentation Profiles
Carvalho, Larissa Anastacio da Costa, Noma, Isabella Harumi Yonehara, Uehara, Adriana Hiromi, Siena, Ádamo Davi Diógenes, Osaki, Luciana Harumi, Mori, Mateus Prates, Pinto, Nadja Cristhina de Souza, Freitas, Vanessa Morais, Junior, Wilson Araújo Silva, Smalley, Keiran S M, Maria-Engler, Silvya Stuchi
Published in Antioxidants (01.05.2024)
Published in Antioxidants (01.05.2024)
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Journal Article
Drepmel—A Multi-Omics Melanoma Drug Repurposing Resource for Prioritizing Drug Combinations and Understanding Tumor Microenvironment
Thompson, Zachary J, Teer, Jamie K, Li, Jiannong, Chen, Zhihua, Welsh, Eric A, Zhang, Yonghong, Ayoubi, Noura, Eroglu, Zeynep, Tan, Aik Choon, Smalley, Keiran S. M, Chen, Yian Ann
Published in Cells (Basel, Switzerland) (01.09.2022)
Published in Cells (Basel, Switzerland) (01.09.2022)
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Journal Article
Long-term effects of BRAF inhibitors in melanoma treatment: friend or foe?
Sloot, Sarah, Fedorenko, Inna V, Smalley, Keiran S M, Gibney, Geoffrey T
Published in Expert opinion on pharmacotherapy (01.04.2014)
Published in Expert opinion on pharmacotherapy (01.04.2014)
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Journal Article
Molecular Pathways: Targeting NRAS in Melanoma and Acute Myelogenous Leukemia
JOHNSON, Douglas B, SMALLEY, Keiran S. M, SOSMAN, Jeffrey A
Published in Clinical cancer research (15.08.2014)
Published in Clinical cancer research (15.08.2014)
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Journal Article
Paradoxical oncogenesis--the long-term effects of BRAF inhibition in melanoma
Gibney, Geoffrey T, Messina, Jane L, Fedorenko, Inna V, Sondak, Vernon K, Smalley, Keiran S M
Published in Nature reviews. Clinical oncology (01.07.2013)
Published in Nature reviews. Clinical oncology (01.07.2013)
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Journal Article
Defining the Conditions for the Generation of Melanocytes from Human Embryonic Stem Cells
Fang, Dong, Leishear, Kim, Nguyen, Thiennga K., Finko, Rena, Cai, Kun, Fukunaga, Mizuho, Li, Ling, Brafford, Patricia A., Kulp, Angela N., Xu, Xiaowei, Smalley, Keiran S. M., Herlyn, Meenhard
Published in Stem cells (Dayton, Ohio) (01.07.2006)
Published in Stem cells (Dayton, Ohio) (01.07.2006)
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Journal Article
PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression
PARAISO, Kim H. T, YUN XIANG, RIBAS, Antoni, DALLA PALMA, Maurizia, NATHANSON, Katherine L, KOOMEN, John M, MESSINA, Jane L, SMALLEY, Keiran S. M, REBECCA, Vito W, ABEL, Ethan V, CHEN, Y. Ann, MUNKO, A. Cecilia, WOOD, Elizabeth, FEDORENKO, Inna V, SONDAK, Vernon K, ANDERSON, Alexander R. A
Published in Cancer research (Chicago, Ill.) (01.04.2011)
Published in Cancer research (Chicago, Ill.) (01.04.2011)
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Journal Article
A Mutational Survey of Acral Nevi
Smalley, Keiran S M, Teer, Jamie K, Chen, Y Ann, Wu, Jheng-Yu, Yao, Jiqiang, Koomen, John M, Chen, Wei-Shen, Rodriguez-Waitkus, Paul, Karreth, Florian A, Messina, Jane L
Published in JAMA dermatology (Chicago, Ill.) (01.07.2021)
Published in JAMA dermatology (Chicago, Ill.) (01.07.2021)
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Journal Article
GP100 expression is variable in intensity in melanoma
Mann, Jacqueline E., Hasson, Nitzan, Su, David G., Adeniran, Adebowale J., Smalley, Keiran S. M., Djureinovic, Dijana, Jilaveanu, Lucia B., Schoenfeld, David A., Kluger, Harriet M.
Published in Cancer Immunology, Immunotherapy : CII (06.08.2024)
Published in Cancer Immunology, Immunotherapy : CII (06.08.2024)
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Journal Article
Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma
Fedorenko, Inna V., Paraiso, Kim H.T., Smalley, Keiran S.M.
Published in Biochemical pharmacology (01.08.2011)
Published in Biochemical pharmacology (01.08.2011)
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