Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase
Miller-Fleming, Leonor, Antas, Pedro, Pais, Teresa Faria, Smalley, Joshua L., Giorgini, Flaviano, Outeiro, Tiago Fleming
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (13.05.2014)
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Journal Article
Adaptive and Behavioral Changes in Kynurenine 3-monooxygenase Knockout Mice: Relevance to Psychotic Disorders
Erhardt, Sophie, Pocivavsek, Ana, Repici, Mariaelena, Liu, Xi-Cong, Imbeault, Sophie, Maddison, Daniel C, Thomas, Marian A.R, Smalley, Joshua L, Larsson, Markus K, Muchowski, Paul J, Giorgini, Flaviano, Schwarcz, Robert
Published in Biological psychiatry (1969) (15.11.2017)
Published in Biological psychiatry (1969) (15.11.2017)
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Journal Article
Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures
Nathanson, Anna J., Zhang, Yihui, Smalley, Joshua L., Ollerhead, Thomas A., Rodriguez Santos, Miguel A., Andrews, Peter M., Wobst, Heike J., Moore, Yvonne E., Brandon, Nicholas J., Hines, Rochelle M., Davies, Paul A., Moss, Stephen J.
Published in Cell reports (Cambridge) (16.07.2019)
Published in Cell reports (Cambridge) (16.07.2019)
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Journal Article
Analyzing the mechanisms that facilitate the subtype-specific assembly of γ -aminobutyric acid type A receptors
Choi, Catherine, Smalley, Joshua L, Lemons, Abigail H S, Ren, Qiu, Bope, Christopher E, Dengler, Jake S, Davies, Paul A, Moss, Stephen J
Published in Frontiers in molecular neuroscience (03.10.2022)
Published in Frontiers in molecular neuroscience (03.10.2022)
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Journal Article
Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy
Kelley, Matt R., Cardarelli, Ross A., Smalley, Joshua L., Ollerhead, Thomas A., Andrew, Peter M., Brandon, Nicholas J., Deeb, Tarek Z., Moss, Stephen J.
Published in EBioMedicine (01.06.2018)
Published in EBioMedicine (01.06.2018)
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Journal Article
Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes
Smalley, Joshua L., Kontou, Georgina, Choi, Catherine, Ren, Qiu, Albrecht, David, Abiraman, Krithika, Santos, Miguel A. Rodriguez, Bope, Christopher E., Deeb, Tarek Z., Davies, Paul A., Brandon, Nicholas J., Moss, Stephen J.
Published in Frontiers in molecular neuroscience (22.10.2020)
Published in Frontiers in molecular neuroscience (22.10.2020)
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Journal Article
The brain-specific kinase LMTK3 regulates neuronal excitability by decreasing KCC2-dependent neuronal Cl− extrusion
Cho, Noell, Kontou, Georgina, Smalley, Joshua L., Bope, Christopher, Dengler, Jacob, Montrose, Kristopher, Deeb, Tarek Z., Brandon, Nicholas J., Yamamoto, Tadashi, Davies, Paul A., Giamas, Georgios, Moss, Stephen J.
Published in iScience (19.04.2024)
Published in iScience (19.04.2024)
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Journal Article
Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis
Varadarajan, Shankar, Tanaka, Kayoko, Smalley, Joshua L, Bampton, Edward T W, Pellecchia, Maurizio, Dinsdale, David, Willars, Gary B, Cohen, Gerald M
Published in PloS one (15.02.2013)
Published in PloS one (15.02.2013)
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Journal Article
Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses
Smalley, Joshua L., Cho, Noell, Ng, Shu Fun Josephine, Choi, Catherine, Lemons, Abigail H. S., Chaudry, Saad, Bope, Christopher E., Dengler, Jake S., Zhang, Chuansheng, Rasband, Matthew N., Davies, Paul A., Moss, Stephen J.
Published in Communications biology (05.01.2023)
Published in Communications biology (05.01.2023)
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Journal Article
The PDE4 inhibitor apremilast modulates ethanol responses in Gabrb1-S409A knock-in mice via PKA-dependent and independent mechanisms
Blednov, Yuri A., Shawlot, William, Homanics, Gregg E., Osterndorff-Kahanek, Elizabeth A., Mason, Sonia, Mayfield, Jody, Smalley, Joshua L., Moss, Stephen J., Messing, Robert O.
Published in Neuropharmacology (01.10.2024)
Published in Neuropharmacology (01.10.2024)
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Journal Article
Glucose and lactate as metabolic constraints on presynaptic transmission at an excitatory synapse
Lucas, Sarah J., Michel, Christophe B., Marra, Vincenzo, Smalley, Joshua L., Hennig, Matthias H., Graham, Bruce P., Forsythe, Ian D.
Published in The Journal of physiology (01.05.2018)
Published in The Journal of physiology (01.05.2018)
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Journal Article
Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes
Madjroh, Nawid, Davies, Paul A., Smalley, Joshua L., Kristiansen, Uffe, Söderhielm, Pella C., Jensen, Anders A.
Published in Pharmacological research (01.07.2021)
Published in Pharmacological research (01.07.2021)
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Journal Article
Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer
Smalley, Munisha, Natarajan, Siva Kumar, Mondal, Jayanta, Best, Douglas, Goldman, David, Shanthappa, Basavaraja, Pellowe, Moriah, Dash, Chinmayee, Saha, Tanmoy, Khiste, Sachin, Ramadurai, Nithya, Eton, Elliot O, Smalley, Joshua L, Brown, Andrew, Thayakumar, Allen, Rahman, Mamunur, Arai, Kazuya, Kohandel, Mohammad, Sengupta, Shiladitya, Goldman, Aaron
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Published in Cancer research (Chicago, Ill.) (01.12.2020)
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Journal Article
KCC2 is required for the survival of mature neurons but not for their development
Kontou, Georgina, Josephine Ng, Shu Fun, Cardarelli, Ross A., Howden, Jack H., Choi, Catherine, Ren, Qiu, Rodriguez Santos, Miguel A., Bope, Christopher E., Dengler, Jake S., Kelley, Matt R., Davies, Paul A., Kittler, Josef T., Brandon, Nicholas J., Moss, Stephen J., Smalley, Joshua L.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington’s disease models
Smalley, Joshua L., Breda, Carlo, Mason, Robert P., Kooner, Gurdeep, Luthi-Carter, Ruth, Gant, Timothy W., Giorgini, Flaviano
Published in Journal of molecular medicine (Berlin, Germany) (01.02.2016)
Published in Journal of molecular medicine (Berlin, Germany) (01.02.2016)
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Journal Article
Identification of a Core Amino Acid Motif within the α Subunit of GABA A Rs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures
Nathanson, Anna J, Zhang, Yihui, Smalley, Joshua L, Ollerhead, Thomas A, Rodriguez Santos, Miguel A, Andrews, Peter M, Wobst, Heike J, Moore, Yvonne E, Brandon, Nicholas J, Hines, Rochelle M, Davies, Paul A, Moss, Stephen J
Published in Cell reports (Cambridge) (16.07.2019)
Published in Cell reports (Cambridge) (16.07.2019)
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Journal Article
Application of connectivity mapping in predictive toxicology based on gene-expression similarity
Smalley, Joshua L, Gant, Timothy W, Zhang, Shu-Dong
Published in Toxicology (Amsterdam) (09.02.2010)
Published in Toxicology (Amsterdam) (09.02.2010)
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Journal Article
Conference Proceeding
Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice
Jarvis, Rebecca, Josephine Ng, Shu Fun, Nathanson, Anna J., Cardarelli, Ross A., Abiraman, Krithika, Wade, Fergus, Evans-Strong, Aidan, Fernandez-Campa, Marina P., Deeb, Tarek Z., Smalley, Joshua L., Jamier, Tanguy, Gurrell, Ian K., McWilliams, Lisa, Kawatkar, Aarti, Conway, Leslie C., Wang, Qi, Burli, Roland W., Brandon, Nicholas J., Chessell, Iain P., Goldman, Aaron J., Maguire, Jamie L., Moss, Stephen J.
Published in Cell reports. Medicine (21.03.2023)
Published in Cell reports. Medicine (21.03.2023)
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Journal Article
A computationally inspired in-vivo approach identifies a link between amygdalar transcriptional heterogeneity, socialization and anxiety
Goldman, Aaron, Smalley, Joshua L., Mistry, Meeta, Krenzlin, Harald, Zhang, Hong, Dhawan, Andrew, Caldarone, Barbara, Moss, Stephen J., Silbersweig, David A., Lawler, Sean E., Braun, Ilana M.
Published in Translational psychiatry (09.12.2019)
Published in Translational psychiatry (09.12.2019)
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Journal Article