Plasmodium falciparum resistance to piperaquine driven by PfCRT
Dhingra, Satish K, Small-Saunders, Jennifer L, Ménard, Didier, Fidock, David A
Published in The Lancet infectious diseases (01.11.2019)
Published in The Lancet infectious diseases (01.11.2019)
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Journal Article
Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance
Small-Saunders, Jennifer L, Hagenah, Laura M, Wicht, Kathryn J, Dhingra, Satish K, Deni, Ioanna, Kim, Jonathan, Vendome, Jeremie, Gil-Iturbe, Eva, Roepe, Paul D, Mehta, Monica, Mancia, Filippo, Quick, Matthias, Eppstein, Margaret J, Fidock, David A
Published in PLoS pathogens (07.02.2022)
Published in PLoS pathogens (07.02.2022)
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Journal Article
Global Spread of Mutant PfCRT and Its Pleiotropic Impact on Plasmodium falciparum Multidrug Resistance and Fitness
Dhingra, Satish K, Gabryszewski, Stanislaw J, Small-Saunders, Jennifer L, Yeo, Tomas, Henrich, Philipp P, Mok, Sachel, Fidock, David A
Published in mBio (30.04.2019)
Published in mBio (30.04.2019)
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Journal Article
Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology
Hagenah, Laura M, Dhingra, Satish K, Small-Saunders, Jennifer L, Qahash, Tarrick, Willems, Andreas, Schindler, Kyra A, Rangel, Gabriel W, Gil-Iturbe, Eva, Kim, Jonathan, Akhundova, Emiliya, Yeo, Tomas, Okombo, John, Mancia, Filippo, Quick, Matthias, Roepe, Paul D, Llinás, Manuel, Fidock, David A
Published in mBio (16.01.2024)
Published in mBio (16.01.2024)
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Journal Article
Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters
McLean, Kyle Jarrod, Straimer, Judith, Hopp, Christine S., Vega-Rodriguez, Joel, Small-Saunders, Jennifer L., Kanatani, Sachie, Tripathi, Abhai, Mlambo, Godfree, Dumoulin, Peter C., Harris, Chantal T., Tong, Xinran, Shears, Melanie J., Ankarklev, Johan, Kafsack, Björn F. C., Fidock, David A., Sinnis, Photini
Published in Scientific reports (11.09.2019)
Published in Scientific reports (11.09.2019)
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Journal Article
Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials
Wicht, Kathryn J, Small-Saunders, Jennifer L, Hagenah, Laura M, Mok, Sachel, Fidock, David A
Published in The Journal of infectious diseases (28.11.2022)
Published in The Journal of infectious diseases (28.11.2022)
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Journal Article
Turning the tide: targeting PfCRT to combat drug-resistant P. falciparum?
Small-Saunders, Jennifer L., Hagenah, Laura M., Fidock, David A.
Published in Nature reviews. Microbiology (01.05.2020)
Published in Nature reviews. Microbiology (01.05.2020)
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Journal Article
Relationship Between Body Composition and Death in Patients with COVID-19 Differs Based on the Presence of Gastrointestinal Symptoms
Nobel, Yael R., Su, Steven H., Anderson, Michaela R., Luk, Lyndon, Small-Saunders, Jennifer L., Reyes-Soffer, Gissette, Gallagher, Dympna, Freedberg, Daniel E.
Published in Digestive diseases and sciences (01.09.2022)
Published in Digestive diseases and sciences (01.09.2022)
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Journal Article
tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum
Small-Saunders, Jennifer L., Sinha, Ameya, Bloxham, Talia S., Hagenah, Laura M., Sun, Guangxin, Preiser, Peter R., Dedon, Peter C., Fidock, David A.
Published in Nature microbiology (01.06.2024)
Published in Nature microbiology (01.06.2024)
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Journal Article
Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54×Cam3.II P. falciparum genetic cross
Kanai, Mariko, Mok, Sachel, Yeo, Tomas, Shears, Melanie J, Ross, Leila S, Jeon, Jin H, Narwal, Sunil, Haile, Meseret T, Tripathi, Abhai K, Mlambo, Godfree, Kim, Jonathan, Gil-Iturbe, Eva, Okombo, John, Fairhurst, Kate J, Bloxham, Talia, Bridgford, Jessica L, Sheth, Tanaya, Ward, Kurt E, Park, Heekuk, Rozenberg, Felix D, Quick, Matthias, Mancia, Filippo, Lee, Marcus C S, Small-Saunders, Jennifer L, Uhlemann, Anne-Catrin, Sinnis, Photini, Fidock, David A
Published in bioRxiv (01.10.2024)
Published in bioRxiv (01.10.2024)
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Journal Article
Body Mass Index and Risk for Intubation or Death in SARS-CoV-2 Infection : A Retrospective Cohort Study
Anderson, Michaela R, Geleris, Joshua, Anderson, David R, Zucker, Jason, Nobel, Yael R, Freedberg, Daniel, Small-Saunders, Jennifer, Rajagopalan, Kartik N, Greendyk, Richard, Chae, Sae-Rom, Natarajan, Karthik, Roh, David, Edwin, Ethan, Gallagher, Dympna, Podolanczuk, Anna, Barr, R Graham, Ferrante, Anthony W, Baldwin, Matthew R
Published in Annals of Internal Medicine (17.11.2020)
Published in Annals of Internal Medicine (17.11.2020)
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Web Resource
Characterization of Bacterial and Fungal Infections in Hospitalized Patients With Coronavirus Disease 2019 and Factors Associated With Health Care-Associated Infections
Kubin, Christine J, McConville, Thomas H, Dietz, Donald, Zucker, Jason, May, Michael, Nelson, Brian, Istorico, Elizabeth, Bartram, Logan, Small-Saunders, Jennifer, Sobieszczyk, Magdalena E, Gomez-Simmonds, Angela, Uhlemann, Anne-Catrin
Published in Open forum infectious diseases (01.06.2021)
Published in Open forum infectious diseases (01.06.2021)
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Journal Article
Outcomes Comparing Initial Short vs Long Course Echinocandin Therapy in Patients with Candidemia Caused by Fluconazole Susceptible Strains
Small-Saunders, Jennifer L, Loo, Angela, Theodore, Deborah, Singh, Amrita, Sobieszczyk, Magdalena, Kubin, Christine J
Published in Open forum infectious diseases (04.10.2017)
Published in Open forum infectious diseases (04.10.2017)
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Journal Article