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Trending topics of SIRT1 in tumorigenicity
Garcia-Peterson, Liz M., Li, Xiaoling
Published in Biochimica et biophysica acta. General subjects (01.09.2021)
Published in Biochimica et biophysica acta. General subjects (01.09.2021)
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Identification of small molecule antagonists of sonic hedgehog/heparin binding with activity in hedgehog functional assays
Lamson, David R., Tarpley, Michael, Addo, Kezia, Ji, Xiaojia, Abu Rabe, Dina, Ehe, Ben, Hughes, Mark, Smith, Ginger R., Daye, Laura R., Musso, David L., Zheng, Weifan, Williams, Kevin P.
Published in Biochimica et biophysica acta. General subjects (01.11.2024)
Published in Biochimica et biophysica acta. General subjects (01.11.2024)
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A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction: Involvement of Akt/eNOS and Nrf2/ARE signaling
Mahmoud, Ayman M., Wilkinson, Fiona L., Jones, Alan M., Wilkinson, James A., Romero, Miguel, Duarte, Juan, Alexander, M. Yvonne
Published in Biochimica et biophysica acta. General subjects (01.01.2017)
Published in Biochimica et biophysica acta. General subjects (01.01.2017)
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Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding
Huerta, Carlos, Jiang, Xin, Trevino, Isaac, Bender, Christopher F., Ferguson, Deborah A., Probst, Brandon, Swinger, Kerren K., Stoll, Vincent S., Thomas, Philip J., Dulubova, Irina, Visnick, Melean, Wigley, W. Christian
Published in Biochimica et biophysica acta (01.11.2016)
Published in Biochimica et biophysica acta (01.11.2016)
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Design of the Global Health chemical diversity library v2 for screening against infectious diseases
Wilson, Caroline, Gardner, J. Mark F., Gray, David W., Baragana, Beatriz, Wyatt, Paul G., Cookson, Alex, Thompson, Stephen, Mendoza-Martinez, Cesar, Bodkin, Michael J., Gilbert, Ian H., Tarver, Gary J.
Published in PLoS neglected tropical diseases (01.12.2023)
Published in PLoS neglected tropical diseases (01.12.2023)
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Targeted genetic and small molecule disruption of N-Ras CaaX cleavage alters its localization and oncogenic potential
Hildebrandt, Emily R., Hussain, Shaneela A., Sieburg, Michelle A., Ravishankar, Rajani, Asad, Nadeem, Gore, Sangram, Ito, Takahiro, Hougland, James L., Dore, Timothy M., Schmidt, Walter K.
Published in Bioorganic chemistry (01.06.2024)
Published in Bioorganic chemistry (01.06.2024)
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UPAR targeted molecular imaging of cancers with small molecule-based probes
Ding, Feng, Chen, Seng, Zhang, Wanshu, Tu, Yufeng, Sun, Yao
Published in Bioorganic & medicinal chemistry (15.10.2017)
Published in Bioorganic & medicinal chemistry (15.10.2017)
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Novel inhibitors of human glucose-6-phosphate dehydrogenase (HsG6PD) affect the activity and stability of the protein
Ramírez-Nava, Edson Jiovany, Hernández-Ochoa, Beatriz, Navarrete-Vázquez, Gabriel, Arreguín-Espinosa, Roberto, Ortega-Cuellar, Daniel, González-Valdez, Abigail, Martínez-Rosas, Víctor, Morales-Luna, Laura, Martínez-Miranda, Josué, Sierra-Palacios, Edgar, Rocha-Ramírez, Luz María, De Franceschi, Lucia, Marcial-Quino, Jaime, Gómez-Manzo, Saúl
Published in Biochimica et biophysica acta. General subjects (01.03.2021)
Published in Biochimica et biophysica acta. General subjects (01.03.2021)
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Development of small molecules targeting the pseudokinase Her3
Lim, Sang Min, Xie, Ting, Westover, Kenneth D., Ficarro, Scott B., Tae, Hyun Seop, Gurbani, Deepak, Sim, Taebo, Marto, Jarrod A., Jänne, Pasi A., Crews, Craig M., Gray, Nathanael S.
Published in Bioorganic & medicinal chemistry letters (15.08.2015)
Published in Bioorganic & medicinal chemistry letters (15.08.2015)
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Enhanced immunostimulatory activity of in silico discovered agonists of Toll-like receptor 2 (TLR2)
Murgueitio, M.S., Ebner, S., Hörtnagl, P., Rakers, C., Bruckner, R., Henneke, P., Wolber, G., Santos-Sierra, S.
Published in Biochimica et biophysica acta. General subjects (01.11.2017)
Published in Biochimica et biophysica acta. General subjects (01.11.2017)
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Interaction of small molecules with polynucleotide repeats and frameshift site RNA
Nemr, Mohamed T. M., Yousif, Mahmoud N. M., Barciszewski, Jan
Published in Archiv der Pharmazie (Weinheim) (01.08.2019)
Published in Archiv der Pharmazie (Weinheim) (01.08.2019)
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Recent Synthetic Approaches towards Small Molecule Reactivators of p53
Silva, Jerson L., Lima, Carolina G. S., Rangel, Luciana P., Ferretti, Giulia D. S., Pauli, Fernanda P., Ribeiro, Ruan C. B., da Silva, Thais de B., da Silva, Fernando C., Ferreira, Vitor F.
Published in Biomolecules (Basel, Switzerland) (20.04.2020)
Published in Biomolecules (Basel, Switzerland) (20.04.2020)
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Chemical activation of a food deprivation signal extends lifespan
Lucanic, Mark, Garrett, Theo, Yu, Ivan, Calahorro, Fernando, Asadi Shahmirzadi, Azar, Miller, Aaron, Gill, Matthew S., Hughes, Robert E., Holden‐Dye, Lindy, Lithgow, Gordon J.
Published in Aging cell (01.10.2016)
Published in Aging cell (01.10.2016)
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Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway
Li, Gang, Diogo, Dorothée, Wu, Di, Spoonamore, Jim, Dancik, Vlado, Franke, Lude, Kurreeman, Fina, Rossin, Elizabeth J., Duclos, Grant, Hartland, Cathy, Zhou, Xuezhong, Li, Kejie, Liu, Jun, De Jager, Philip L., Siminovitch, Katherine A., Zhernakova, Alexandra, Raychaudhuri, Soumya, Bowes, John, Eyre, Steve, Padyukov, Leonid, Gregersen, Peter K., Worthington, Jane, Gupta, Namrata, Clemons, Paul A., Stahl, Eli, Tolliday, Nicola, Plenge, Robert M.
Published in PLoS genetics (01.05.2013)
Published in PLoS genetics (01.05.2013)
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