The fecal metabolome as a functional readout of the gut microbiome
Zierer, Jonas, Jackson, Matthew A, Kastenmüller, Gabi, Mangino, Massimo, Long, Tao, Telenti, Amalio, Mohney, Robert P, Small, Kerrin S, Bell, Jordana T, Steves, Claire J, Valdes, Ana M, Spector, Tim D, Menni, Cristina
Published in Nature genetics (01.06.2018)
Published in Nature genetics (01.06.2018)
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Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements
Grundberg, Elin, Meduri, Eshwar, Sandling, Johanna K., Hedman, Åsa K., Keildson, Sarah, Buil, Alfonso, Busche, Stephan, Yuan, Wei, Nisbet, James, Sekowska, Magdalena, Wilk, Alicja, Barrett, Amy, Small, Kerrin S., Ge, Bing, Caron, Maxime, Shin, So-Youn, Ahmadi, Kourosh R., Ainali, Chrysanthi, Barrett, Amy, Bataille, Veronique, Bell, Jordana T., Buil, Alfonso, Deloukas, Panos, Dermitzakis, Emmanouil T., Dimas, Antigone S., Durbin, Richard, Glass, Daniel, Grundberg, Elin, Hassanali, Neelam, Hedman, Åsa K., Ingle, Catherine, Knowles, David, Krestyaninova, Maria, Lindgren, Cecilia M., Lowe, Christopher E., McCarthy, Mark I., Meduri, Eshwar, di Meglio, Paola, Min, Josine L., Montgomery, Stephen B., Nestle, Frank O., Nica, Alexandra C., Nisbet, James, O’Rahilly, Stephen, Parts, Leopold, Potter, Simon, Sandling, Johanna, Sekowska, Magdalena, Shin, So-Youn, Small, Kerrin S., Soranzo, Nicole, Spector, Tim D., Surdulescu, Gabriela, Travers, Mary E., Tsaprouni, Loukia, Tsoka, Sophia, Wilk, Alicja, Yang, Tsun-Po, Zondervan, Krina T., Lathrop, Mark, Dermitzakis, Emmanouil T., McCarthy, Mark I., Spector, Timothy D., Bell, Jordana T., Deloukas, Panos
Published in American journal of human genetics (07.11.2013)
Published in American journal of human genetics (07.11.2013)
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Journal Article
Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable
Zito, Antonino, Roberts, Amy L, Visconti, Alessia, Rossi, Niccolo', Andres-Ejarque, Rosa, Nardone, Stefano, El-Sayed Moustafa, Julia S, Falchi, Mario, Small, Kerrin S
Published in PLoS genetics (21.02.2023)
Published in PLoS genetics (21.02.2023)
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Journal Article
Human metabolic individuality in biomedical and pharmaceutical research
SUHRE, Karsten, SHIN, So-Youn, HAMMOND, Christopher J, HRABE DEANGELIS, Martin, KASTENMÜLLER, Gabi, KÖTTGEN, Anna, KRONENBERG, Florian, MANGINO, Massimo, MEISINGER, Christa, MEITINGER, Thomas, MEWES, Hans-Werner, MILBURN, Michael V, PETERSEN, Ann-Kristin, PREHN, Cornelia, RAFFLER, Johannes, RIED, Janina S, RÖMISCH-MARG, Werner, SAMANI, Nilesh J, SMALL, Kerrin S, WICHMANN, H.-Erich, GUANGJUZHAI, ILLIG, Thomas, SPECTOR, Tim D, MOHNEY, Robert P, ADAMSKI, Jerzy, SORANZO, Nicole, GIEGER, Christian, MEREDITH, David, WÄGELE, Brigitte, ALTMAIER, Elisabeth, DELOUKAS, Panos, ERDMANN, Jeanette, GRUNDBERG, Elin
Published in Nature (London) (01.09.2011)
Published in Nature (London) (01.09.2011)
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Journal Article
Methodological challenges of genome-wide association analysis in Africa
Kwiatkowski, Dominic P, Teo, Yik-Ying, Small, Kerrin S
Published in Nature reviews. Genetics (01.02.2010)
Published in Nature reviews. Genetics (01.02.2010)
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Journal Article
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
Bell, Jordana T, Tsai, Pei-Chien, Yang, Tsun-Po, Pidsley, Ruth, Nisbet, James, Glass, Daniel, Mangino, Massimo, Zhai, Guangju, Zhang, Feng, Valdes, Ana, Shin, So-Youn, Dempster, Emma L, Murray, Robin M, Grundberg, Elin, Hedman, Asa K, Nica, Alexandra, Small, Kerrin S, Dermitzakis, Emmanouil T, McCarthy, Mark I, Mill, Jonathan, Spector, Tim D, Deloukas, Panos
Published in PLoS genetics (01.04.2012)
Published in PLoS genetics (01.04.2012)
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Journal Article
Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits
Civelek, Mete, Wu, Ying, Pan, Calvin, Raulerson, Chelsea K., Ko, Arthur, He, Aiqing, Tilford, Charles, Saleem, Niyas K., Stančáková, Alena, Scott, Laura J., Fuchsberger, Christian, Stringham, Heather M., Jackson, Anne U., Narisu, Narisu, Chines, Peter S., Small, Kerrin S., Kuusisto, Johanna, Parks, Brian W., Pajukanta, Päivi, Kirchgessner, Todd, Collins, Francis S., Gargalovic, Peter S., Boehnke, Michael, Laakso, Markku, Mohlke, Karen L., Lusis, Aldons J.
Published in American journal of human genetics (02.03.2017)
Published in American journal of human genetics (02.03.2017)
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Journal Article
Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition
Small, Kerrin S, Todorčević, Marijana, Civelek, Mete, El-Sayed Moustafa, Julia S, Wang, Xiao, Simon, Michelle M, Fernandez-Tajes, Juan, Mahajan, Anubha, Horikoshi, Momoko, Hugill, Alison, Glastonbury, Craig A, Quaye, Lydia, Neville, Matt J, Sethi, Siddharth, Yon, Marianne, Pan, Calvin, Che, Nam, Viñuela, Ana, Tsai, Pei-Chien, Nag, Abhishek, Buil, Alfonso, Thorleifsson, Gudmar, Raghavan, Avanthi, Ding, Qiurong, Morris, Andrew P, Bell, Jordana T, Thorsteinsdottir, Unnur, Stefansson, Kari, Laakso, Markku, Dahlman, Ingrid, Arner, Peter, Gloyn, Anna L, Musunuru, Kiran, Lusis, Aldons J, Cox, Roger D, Karpe, Fredrik, McCarthy, Mark I
Published in Nature genetics (01.04.2018)
Published in Nature genetics (01.04.2018)
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Journal Article
Nuclear genetic regulation of the human mitochondrial transcriptome
Ali, Aminah T, Boehme, Lena, Carbajosa, Guillermo, Seitan, Vlad C, Small, Kerrin S, Hodgkinson, Alan
Published in eLife (18.02.2019)
Published in eLife (18.02.2019)
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Journal Article
Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
Zito, Antonino, Davies, Matthew N, Tsai, Pei-Chien, Roberts, Susanna, Andres-Ejarque, Rosa, Nardone, Stefano, Bell, Jordana T, Wong, Chloe C Y, Small, Kerrin S
Published in Nature communications (25.11.2019)
Published in Nature communications (25.11.2019)
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Journal Article
Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS
Pan, David Z, Garske, Kristina M, Alvarez, Marcus, Bhagat, Yash V, Boocock, James, Nikkola, Elina, Miao, Zong, Raulerson, Chelsea K, Cantor, Rita M, Civelek, Mete, Glastonbury, Craig A, Small, Kerrin S, Boehnke, Michael, Lusis, Aldons J, Sinsheimer, Janet S, Mohlke, Karen L, Laakso, Markku, Pajukanta, Päivi, Ko, Arthur
Published in Nature communications (17.04.2018)
Published in Nature communications (17.04.2018)
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Journal Article
RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro
Loh, Nellie Y, Minchin, James E N, Pinnick, Katherine E, Verma, Manu, Todorčević, Marijana, Denton, Nathan, Moustafa, Julia El-Sayed, Kemp, John P, Gregson, Celia L, Evans, David M, Neville, Matt J, Small, Kerrin S, McCarthy, Mark I, Mahajan, Anubha, Rawls, John F, Karpe, Fredrik, Christodoulides, Constantinos
Published in Nature communications (03.06.2020)
Published in Nature communications (03.06.2020)
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Journal Article
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins
Yuan, Wei, Xia, Yudong, Bell, Christopher G, Yet, Idil, Ferreira, Teresa, Ward, Kirsten J, Gao, Fei, Loomis, A Katrina, Hyde, Craig L, Wu, Honglong, Lu, Hanlin, Liu, Yuan, Small, Kerrin S, Viñuela, Ana, Morris, Andrew P, Berdasco, María, Esteller, Manel, Brosnan, M Julia, Deloukas, Panos, McCarthy, Mark I, John, Sally L, Bell, Jordana T, Wang, Jun, Spector, Tim D
Published in Nature communications (12.12.2014)
Published in Nature communications (12.12.2014)
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Journal Article
Adiposity-Dependent Regulatory Effects on Multi-tissue Transcriptomes
Glastonbury, Craig A., Viñuela, Ana, Buil, Alfonso, Halldorsson, Gisli H., Thorleifsson, Gudmar, Helgason, Hannes, Thorsteinsdottir, Unnur, Stefansson, Kari, Dermitzakis, Emmanouil T., Spector, Tim D., Small, Kerrin S.
Published in American journal of human genetics (01.09.2016)
Published in American journal of human genetics (01.09.2016)
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Journal Article
Analysis of subcellular RNA fractions demonstrates significant genetic regulation of gene expression in human brain post-transcriptionally
D’Sa, Karishma, Guelfi, Sebastian, Vandrovcova, Jana, Reynolds, Regina H., Zhang, David, Hardy, John, Botía, Juan A., Weale, Michael E., Taliun, Sarah A. Gagliano, Small, Kerrin S., Ryten, Mina
Published in Scientific reports (24.08.2023)
Published in Scientific reports (24.08.2023)
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Journal Article
Detecting and Characterizing Genomic Signatures of Positive Selection in Global Populations
Liu, Xuanyao, Ong, Rick Twee-Hee, Pillai, Esakimuthu Nisha, Elzein, Abier M., Small, Kerrin S., Clark, Taane G., Kwiatkowski, Dominic P., Teo, Yik-Ying
Published in American journal of human genetics (06.06.2013)
Published in American journal of human genetics (06.06.2013)
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Journal Article
Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health
Tsai, Pei-Chien, Glastonbury, Craig A, Eliot, Melissa N, Bollepalli, Sailalitha, Yet, Idil, Castillo-Fernandez, Juan E, Carnero-Montoro, Elena, Hardiman, Thomas, Martin, Tiphaine C, Vickers, Alice, Mangino, Massimo, Ward, Kirsten, Pietiläinen, Kirsi H, Deloukas, Panos, Spector, Tim D, Viñuela, Ana, Loucks, Eric B, Ollikainen, Miina, Kelsey, Karl T, Small, Kerrin S, Bell, Jordana T
Published in Clinical epigenetics (20.10.2018)
Published in Clinical epigenetics (20.10.2018)
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Journal Article
A genotype calling algorithm for the Illumina BeadArray platform
Teo, Yik Y., Inouye, Michael, Small, Kerrin S., Gwilliam, Rhian, Deloukas, Panagiotis, Kwiatkowski, Dominic P., Clark, Taane G.
Published in Bioinformatics (15.10.2007)
Published in Bioinformatics (15.10.2007)
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Journal Article
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations
Teo, Yik-Ying, Sim, Xueling, Ong, Rick T H, Tan, Adrian K S, Chen, Jieming, Tantoso, Erwin, Small, Kerrin S, Ku, Chee-Seng, Lee, Edmund J D, Seielstad, Mark, Chia, Kee-Seng
Published in Genome research (01.11.2009)
Published in Genome research (01.11.2009)
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Journal Article
Further evidence supporting a potential role for ADH1B in obesity
Morales, Liza D, Cromack, Douglas T, Tripathy, Devjit, Fourcaudot, Marcel, Kumar, Satish, Curran, Joanne E, Carless, Melanie, Göring, Harald H H, Hu, Shirley L, Lopez-Alvarenga, Juan Carlos, Garske, Kristina M, Pajukanta, Päivi, Small, Kerrin S, Glastonbury, Craig A, Das, Swapan K, Langefeld, Carl, Hanson, Robert L, Hsueh, Wen-Chi, Norton, Luke, Arya, Rector, Mummidi, Srinivas, Blangero, John, DeFronzo, Ralph A, Duggirala, Ravindranath, Jenkinson, Christopher P
Published in Scientific reports (21.01.2021)
Published in Scientific reports (21.01.2021)
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