Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Zetsche, Bernd, Gootenberg, Jonathan S., Abudayyeh, Omar O., Slaymaker, Ian M., Makarova, Kira S., Essletzbichler, Patrick, Volz, Sara E., Joung, Julia, van der Oost, John, Regev, Aviv, Koonin, Eugene V., Zhang, Feng
Published in Cell (22.10.2015)
Published in Cell (22.10.2015)
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Journal Article
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
Yamano, Takashi, Nishimasu, Hiroshi, Zetsche, Bernd, Hirano, Hisato, Slaymaker, Ian M., Li, Yinqing, Fedorova, Iana, Nakane, Takanori, Makarova, Kira S., Koonin, Eugene V., Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu
Published in Cell (05.05.2016)
Published in Cell (05.05.2016)
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Journal Article
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
Abudayyeh, Omar O., Gootenberg, Jonathan S., Konermann, Silvana, Joung, Julia, Slaymaker, Ian M., Cox, David B. T., Shmakov, Sergey, Makarova, Kira S., Semenova, Ekaterina, Minakhin, Leonid, Severinov, Konstantin, Regev, Aviv, Lander, Eric S., Koonin, Eugene V., Zhang, Feng
Published in Science (American Association for the Advancement of Science) (05.08.2016)
Published in Science (American Association for the Advancement of Science) (05.08.2016)
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Journal Article
Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28
Smargon, Aaron A., Cox, David B.T., Pyzocha, Neena K., Zheng, Kaijie, Slaymaker, Ian M., Gootenberg, Jonathan S., Abudayyeh, Omar A., Essletzbichler, Patrick, Shmakov, Sergey, Makarova, Kira S., Koonin, Eugene V., Zhang, Feng
Published in Molecular cell (16.02.2017)
Published in Molecular cell (16.02.2017)
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Journal Article
Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits
Platt, Randall J., Zhou, Yang, Slaymaker, Ian M., Shetty, Ashwin S., Weisbach, Niels R., Kim, Jin-Ah, Sharma, Jitendra, Desai, Mitul, Sood, Sabina, Kempton, Hannah R., Crabtree, Gerald R., Feng, Guoping, Zhang, Feng
Published in Cell reports (Cambridge) (11.04.2017)
Published in Cell reports (Cambridge) (11.04.2017)
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Journal Article
High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage
Slaymaker, Ian M., Mesa, Pablo, Kellner, Max J., Kannan, Soumya, Brignole, Edward, Koob, Jeremy, Feliciano, Patricia R., Stella, Stefano, Abudayyeh, Omar O., Gootenberg, Jonathan S., Strecker, Jonathan, Montoya, Guillermo, Zhang, Feng
Published in Cell reports (Cambridge) (26.03.2019)
Published in Cell reports (Cambridge) (26.03.2019)
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Journal Article
High-resolution structure of cas13b and biochemical characterization of RNA targeting and cleavage
Slaymaker, Ian M., Mesa, Pablo, Kellner, Max J., Kannan, Soumya, Brignole, Edward, Koob, Jeremy, Feliciano, Patricia R., Stella, Stefano, Abudayyeh, Omar O., Gootenberg, Jonathan S., Strecker, Jonathan, Montoya, Guillermo, Zhang, Feng
Published in Cell reports (Cambridge) (09.03.2021)
Published in Cell reports (Cambridge) (09.03.2021)
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Journal Article
Base editing: advances and therapeutic opportunities
Porto, Elizabeth M., Komor, Alexis C., Slaymaker, Ian M., Yeo, Gene W.
Published in Nature reviews. Drug discovery (01.12.2020)
Published in Nature reviews. Drug discovery (01.12.2020)
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Journal Article
Engineering Cas9 for human genome editing
Slaymaker, Ian M., Gaudelli, Nicole M.
Published in Current opinion in structural biology (01.08.2021)
Published in Current opinion in structural biology (01.08.2021)
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Journal Article
Directed evolution of adenine base editors with increased activity and therapeutic application
Gaudelli, Nicole M., Lam, Dieter K., Rees, Holly A., Solá-Esteves, Noris M., Barrera, Luis A., Born, David A., Edwards, Aaron, Gehrke, Jason M., Lee, Seung-Joo, Liquori, Alexander J., Murray, Ryan, Packer, Michael S., Rinaldi, Conrad, Slaymaker, Ian M., Yen, Jonathan, Young, Lauren E., Ciaramella, Giuseppe
Published in Nature biotechnology (01.07.2020)
Published in Nature biotechnology (01.07.2020)
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Journal Article
Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation
Chu, S Haihua, Packer, Michael, Rees, Holly, Lam, Dieter, Yu, Yi, Marshall, Jeffrey, Cheng, Lo-I, Lam, Daisy, Olins, Jenny, Ran, Fei Ann, Liquori, Alexander, Gantzer, Bob, Decker, Jeremy, Born, David, Barrera, Luis, Hartigan, Adam, Gaudelli, Nicole, Ciaramella, Giuseppe, Slaymaker, Ian M
Published in CRISPR journal (01.04.2021)
Published in CRISPR journal (01.04.2021)
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Journal Article
CRISPR–Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling
Tangprasertchai, Narin S, Di Felice, Rosa, Zhang, Xiaojun, Slaymaker, Ian M, Vazquez Reyes, Carolina, Jiang, Wei, Rohs, Remo, Qin, Peter Z
Published in ACS chemical biology (16.06.2017)
Published in ACS chemical biology (16.06.2017)
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Journal Article
Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology
Slaymaker, Ian M, Fu, Yang, Toso, Daniel B, Ranatunga, Nimna, Brewster, Aaron, Forsburg, Susan L, Zhou, Z Hong, Chen, Xiaojiang S
Published in Nucleic acids research (01.03.2013)
Published in Nucleic acids research (01.03.2013)
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Journal Article
Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase
Slaymaker, Ian M., Bracey, Michael, Mileni, Mauro, Garfunkle, Joie, Cravatt, Benjamin F., Boger, Dale L., Stevens, Raymond C.
Published in Bioorganic & medicinal chemistry (15.11.2008)
Published in Bioorganic & medicinal chemistry (15.11.2008)
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Journal Article
CRISPR Cas9 Mediated DNA Unwinding Detected using Site-Directed Spin Labeling
Tangprasertchai, Narin S., Di Felice, Rosa, Zhang, Xiaojun, Slaymaker, Ian M., Vazquez Reyes, Carolina, Jiang, Wei, Rohs, Remo, Qin, Peter
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Journal Article
123 Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology
Slaymaker, Ian M., Fu, Yang, Toso, Daniel B., Ranatunga, Nimna, Brewster, Aaron, Forsburg, Susan L., Hong Zhou, Z., Chen, Xiaojiang S.
Published in Journal of biomolecular structure & dynamics (01.01.2013)
Published in Journal of biomolecular structure & dynamics (01.01.2013)
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