Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway
Herbertz, Stephan, Sawyer, J Scott, Stauber, Anja J, Gueorguieva, Ivelina, Driscoll, Kyla E, Estrem, Shawn T, Cleverly, Ann L, Desaiah, Durisala, Guba, Susan C, Benhadji, Karim A, Slapak, Christopher A, Lahn, Michael M
Published in Drug design, development and therapy (01.01.2015)
Published in Drug design, development and therapy (01.01.2015)
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A first-in-human phase 1 study of a hepcidin monoclonal antibody, LY2787106, in cancer-associated anemia
Vadhan-Raj, Saroj, Abonour, Rafat, Goldman, Jonathan W, Smith, David A, Slapak, Christopher A, Ilaria, Jr, Robert L, Tiu, Ramon V, Wang, Xuejing, Callies, Sophie, Cox, Joanne, Tuttle, Jay L, Lau, Yiu-Keung, Roeland, Eric J
Published in Journal of hematology and oncology (21.03.2017)
Published in Journal of hematology and oncology (21.03.2017)
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Phase II Study of Enzastaurin, a Protein Kinase C Beta Inhibitor, in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
ROBERTSON, Michael J, KAHL, Brad S, DARSTEIN, Christelle, ENAS, Nathan, KUTOK, Jeffery L, ASTER, Jon C, NEUBERG, Donna, SAVAGE, Kerry J, LACASCE, Ann, THORNTON, Donald, SLAPAK, Christopher A, SHIPP, Margaret A, VOSE, Julie M, DE VOS, Sven, LAUGHLIN, Mary, FLYNN, Patrick J, ROWLAND, Kendrith, CRUZ, José C, GOLDBERG, Stuart L, MUSIB, Luna
Published in Journal of clinical oncology (01.05.2007)
Published in Journal of clinical oncology (01.05.2007)
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An increase in the expression of ribonucleotide reductase large subunit 1 is associated with gemcitabine resistance in non-small cell lung cancer cell lines
DAVIDSON, Jennifer D, LIANDONG MA, FLAGELLA, Michael, GEEGANAGE, Sandaruwan, GELBERT, Lawrence M, SLAPAK, Christopher A
Published in Cancer research (Chicago, Ill.) (01.06.2004)
Published in Cancer research (Chicago, Ill.) (01.06.2004)
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Oral Administration of Gemcitabine in Patients with Refractory Tumors: A Clinical and Pharmacologic Study
Veltkamp, Stephan A, Jansen, Robert S, Callies, Sophie, Pluim, Dick, Visseren-Grul, Carla M, Rosing, Hilde, Kloeker-Rhoades, Susanne, Andre, Valerie A M, Beijnen, Jos H, Slapak, Christopher A, Schellens, Jan H M
Published in Clinical cancer research (01.06.2008)
Published in Clinical cancer research (01.06.2008)
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A Phase I Trial of a Potent P-Glycoprotein Inhibitor, Zosuquidar Trihydrochloride (LY335979), Administered Intravenously in Combination with Doxorubicin in Patients with Advanced Malignancy
SANDLER, Alan, GORDON, Michael, JORDAN, Christopher, BURGESS, Michael, SLAPAK, Christopher A, DE ALWIS, Dinesh P, POULIQUEN, Isabelle, GREEN, Lisa, MARDER, Phil, CHAUDHARY, Ajai, FIFE, Karen, BATTIATO, Linda, SWEENEY, Christopher
Published in Clinical cancer research (15.05.2004)
Published in Clinical cancer research (15.05.2004)
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Phase I Study of Docetaxel in Combination with the P-Glycoprotein Inhibitor, Zosuquidar, in Resistant Malignancies
FRACASSE, Paula M, GOLDSTEIN, Lori J, BURGESS, Michael F, SLAPAK, Christopher A, SCHELLENS, Jan H. M, DE ALWIS, Dinesh P, RADER, Janet S, ARQUETTE, Matthew A, GOODNER, Sherry A, WRIGHT, Lisa P, FEARS, Carole L, GAZAK, Robert J, ANDRE, Valerie A. M
Published in Clinical cancer research (01.11.2004)
Published in Clinical cancer research (01.11.2004)
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A Phase I Trial of a Potent P-Glycoprotein Inhibitor, Zosuquidar.3HCl Trihydrochloride (LY335979), Administered Orally in Combination with Doxorubicin in Patients with Advanced Malignancies
RUBIN, Eric H, DE ALWIS, Dinesh P, MUCH, Judy, KANE, Michael, CHAUDHARY, Ajai, JORDAN, Christopher, BURGESS, Michael, SLAPAK, Christopher A, POULIQUEN, Isabelle, GREEN, Lisa, MARDER, Phil, YONG LIN, MUSANTI, Rita, GROSPE, Stephanie L, SMITH, Sharon L, TOPPMEYER, Deborah L
Published in Clinical cancer research (01.12.2002)
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Published in Clinical cancer research (01.12.2002)
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Abrogation of Mitochondrial Cytochrome c Release and Caspase-3 Activation in Acquired Multidrug Resistance
Kojima, H, Endo, K, Moriyama, H, Tanaka, Y, Alnemri, E S, Slapak, C A, Teicher, B, Kufe, D, Datta, R
Published in The Journal of biological chemistry (03.07.1998)
Published in The Journal of biological chemistry (03.07.1998)
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A very early induction of major vault protein accompanied by increased drug resistance in U‐937 cells
Hu, Yi, Stephen, Andrew G., Cao, Jin, Tanzer, Lee R., Slapak, Christopher A., Harrison, Steadman D., Devanarayan, Viswanath, Dantzig, Anne H., Starling, James J., Rome, Leonard H., Moore, Robert E.
Published in International journal of cancer (10.01.2002)
Published in International journal of cancer (10.01.2002)
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Results of a Phase 1 Study of AME-133v (LY2469298), an Fc-Engineered Humanized Monoclonal Anti-CD20 Antibody, in FcγRIIIa-Genotyped Patients with Previously Treated Follicular Lymphoma
FORERO-TORRES, Andres, DE VOS, Sven, SMITH, Mitchell R, LINK, Brian K, WOOLDRIDGE, James E, GANJOO, Kristen N, POHLMAN, Brad L, PASHKEVICH, Maksim, CRONIER, Damien M, DANG, Nam H, CARPENTER, Susan P, ALLAN, Barrett W, NELSON, James G, SLAPAK, Christopher A
Published in Clinical cancer research (01.03.2012)
Published in Clinical cancer research (01.03.2012)
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Identification and Characterization of the Canine Multidrug Resistance-associated Protein
Ma, Liandong, Pratt, Susan E, Cao, Jin, Dantzig, Anne H, Moore, Robert E, Slapak, Christopher A
Published in Molecular cancer therapeutics (01.12.2002)
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Published in Molecular cancer therapeutics (01.12.2002)
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Phase I study of oral gemcitabine prodrug (LY2334737) in Japanese patients with advanced solid tumors
Yamamoto, Noboru, Nokihara, Hiroshi, Yamada, Yasuhide, Uenaka, Kazunori, Sekiguchi, Risa, Makiuchi, Takeshi, Slapak, Christopher A., Benhadji, Karim A., Tamura, Tomohide
Published in Cancer chemotherapy and pharmacology (01.06.2013)
Published in Cancer chemotherapy and pharmacology (01.06.2013)
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Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP-binding cassette (ABC) drug transporters
Dantzig, Anne H., Shepard, Robert L., Pratt, Susan E., Tabas, Linda B., Lander, Peter A., Ma, Liandong, Paul, Donald C., Williams, Daniel C., Peng, Sheng-Bin, Slapak, Christopher A., Godinot, Nathalie, Perry, William L.
Published in Biochemical pharmacology (15.03.2004)
Published in Biochemical pharmacology (15.03.2004)
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Phase I Study of Oral Gemcitabine Prodrug (LY2334737) Alone and in Combination with Erlotinib in Patients with Advanced Solid Tumors
KOOLEN, Stijn L. W, WITTEVEEN, Petronella O, BEIJNEN, Jos H, VOEST, Emile E, SCHELLENS, Jan H. M, JANSEN, Robert S, LANGENBERG, Marlies H. G, KRONEMEIJER, Roelien H, NOL, Annemarie, GARCIA-RIBAS, Ignacio, CALLIES, Sophie, BENHADJI, Karim A, SLAPAK, Christopher A
Published in Clinical cancer research (15.09.2011)
Published in Clinical cancer research (15.09.2011)
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A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity
Inhorn, R C, Aster, J C, Roach, S A, Slapak, C A, Soiffer, R, Tantravahi, R, Stone, R M
Published in Blood (01.04.1995)
Published in Blood (01.04.1995)
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Phase 1/2 Study of Ocaratuzumab, an Fc-Engineered Humanized Anti-CD20 Monoclonal Antibody, in Low-Affinity FcγRIIIa Patients with Previously Treated Follicular Lymphoma
Ganjoo, Kristen N., de Vos, Sven, Pohlman, Brad L., Flinn, Ian W., Forero-Torres, Andres, Enas, Nathan H., Cronier, Damien M., Dang, Nam H., Foon, Kenneth A., Carpenter, Susan P., Slapak, Christopher A., Link, Brian K., Smith, Mitchell R., Mapara, Markus Y., Wooldridge, James E.
Published in Leukemia & lymphoma (01.01.2015)
Published in Leukemia & lymphoma (01.01.2015)
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