Polyploidy control in hepatic health and disease
Sladky, Valentina C., Eichin, Felix, Reiberger, Thomas, Villunger, Andreas
Published in Journal of hepatology (01.11.2021)
Published in Journal of hepatology (01.11.2021)
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Journal Article
The PIDDosome activates p53 in response to supernumerary centrosomes
Fava, Luca L, Schuler, Fabian, Sladky, Valentina, Haschka, Manuel D, Soratroi, Claudia, Eiterer, Lisa, Demetz, Egon, Weiss, Guenter, Geley, Stephan, Nigg, Erich A, Villunger, Andreas
Published in Genes & development (01.01.2017)
Published in Genes & development (01.01.2017)
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Journal Article
PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis
Kim, Ju Youn, Wang, Lily Q., Sladky, Valentina C., Oh, Tae Gyu, Liu, Junlai, Trinh, Kaitlyn, Eichin, Felix, Downes, Michael, Hosseini, Mojgan, Jacotot, Etienne D., Evans, Ronald M., Villunger, Andreas, Karin, Michael
Published in Cell metabolism (04.10.2022)
Published in Cell metabolism (04.10.2022)
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Journal Article
E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration
Sladky, Valentina C., Knapp, Katja, Soratroi, Claudia, Heppke, Julia, Eichin, Felix, Rocamora-Reverte, Lourdes, Szabo, Tamas G., Bongiovanni, Laura, Westendorp, Bart, Moreno, Eva, van Liere, Elsbeth A., Bakker, Bjorn, Spierings, Diana C.J., Wardenaar, René, Pereyra, David, Starlinger, Patrick, Schultze, Simon, Trauner, Michael, Stojakovic, Tatjana, Scharnagl, Hubert, Fava, Luca L., Foijer, Floris, de Bruin, Alain, Villunger, Andreas
Published in Developmental cell (10.02.2020)
Published in Developmental cell (10.02.2020)
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Journal Article
Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis
Lambrecht, Rebekka, Rudolf, Franziska, Ückert, Anna-Katharina, Sladky, Valentina C., Phan, Truong San, Jansen, Jasmin, Naim, Samara, Kaufmann, Thomas, Keogh, Adrian, Kirschnek, Susanne, Mangerich, Aswin, Stengel, Florian, Leist, Marcel, Villunger, Andreas, Brunner, Thomas
Published in Cell death and differentiation (01.01.2024)
Published in Cell death and differentiation (01.01.2024)
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Journal Article
PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis
Sladky, Valentina C, Knapp, Katja, Szabo, Tamas G, Braun, Vincent Z, Bongiovanni, Laura, van den Bos, Hilda, Spierings, Diana CJ, Westendorp, Bart, Curinha, Ana, Stojakovic, Tatjana, Scharnagl, Hubert, Timelthaler, Gerald, Tsuchia, Kaoru, Pinter, Matthias, Semmler, Georg, Foijer, Floris, de Bruin, Alain, Reiberger, Thomas, Rohr‐Udilova, Nataliya, Villunger, Andreas
Published in EMBO reports (03.12.2020)
Published in EMBO reports (03.12.2020)
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Journal Article
Centriole signaling restricts hepatocyte ploidy to maintain liver integrity
Sladky, Valentina C, Akbari, Hanan, Tapias-Gomez, Daniel, Evans, Lauren T, Drown, Chelsea G, Strong, Margaret A, LoMastro, Gina M, Larman, Tatianna, Holland, Andrew J
Published in Genes & development (01.07.2022)
Published in Genes & development (01.07.2022)
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Journal Article
Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability
Sheikh, Taimoor I., Vasli, Nasim, Pastore, Stephen, Kharizi, Kimia, Harripaul, Ricardo, Fattahi, Zohreh, Pande, Shruti, Naeem, Farooq, Hussain, Abrar, Mir, Asif, Islam, Omar, Girisha, Katta Mohan, Irfan, Muhammad, Ayub, Muhammad, Schwarzer, Christoph, Najmabadi, Hossein, Shukla, Anju, Sladky, Valentina C., Braun, Vincent Zoran, Garcia-Carpio, Irmina, Villunger, Andreas, Vincent, John B.
Published in Translational psychiatry (05.01.2021)
Published in Translational psychiatry (05.01.2021)
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Journal Article
BOK promotes chemical-induced hepatocarcinogenesis in mice
Rabachini, Tatiana, Fernandez-Marrero, Yuniel, Montani, Matteo, Loforese, Giulio, Sladky, Valentina, He, Zhaoyue, Bachmann, Daniel, Wicki, Simone, Villunger, Andreas, Stroka, Deborah, Kaufmann, Thomas
Published in Cell death and differentiation (01.03.2018)
Published in Cell death and differentiation (01.03.2018)
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Journal Article
Piddosome-controlled liver ploidy is predictive for HCC outcome
Sladky, Valentina, Knapp, Katja, Tsuchiya, Kaoru, Bongiovanni, Laura, Westendorp, Bart, Szabo, Tamas, Timelthaler, Gerald, Eferl, Robert, Sieghart, Wolfgang, Peck-Radosavljevic, Markus, Herac, Merima, Stift, Judith, Oberhuber, Georg, Stojakovic, Tatjana, Schargl, Hubert, van den Bos, Hilda, Spierings, Diana, Foijer, Floris, de Bruin, Alain, Pinter, Matthias, Reiberger, Thomas, Rohr-Udilova, Nataliya, Villunger, Andreas
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
FRI503 - Piddosome-controlled liver ploidy is predictive for HCC outcome
Sladky, Valentina, Knapp, Katja, Tsuchiya, Kaoru, Bongiovanni, Laura, Westendorp, Bart, Szabo, Tamas, Timelthaler, Gerald, Eferl, Robert, Sieghart, Wolfgang, Peck-Radosavljevic, Markus, Herac, Merima, Stift, Judith, Oberhuber, Georg, Stojakovic, Tatjana, Schargl, Hubert, van den Bos, Hilda, Spierings, Diana, Foijer, Floris, de Bruin, Alain, Pinter, Matthias, Reiberger, Thomas, Rohr-Udilova, Nataliya, Villunger, Andreas
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
The AID2 system offers a potent tool for rapid, reversible, or sustained degradation of essential proteins in live mice
Sladky, Valentina C, Strong, Margaret A, Tapias-Gomez, Daniel, Jewett, Cayla E, Drown, Chelsea G, Scott, Phillip M, Holland, Andrew J
Published in bioRxiv (04.06.2024)
Published in bioRxiv (04.06.2024)
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Journal Article
PIDDosome-induced p53-activation for ploidy restriction facilitates hepatocarcinogenesis
Sladky, Valentina C, Knapp, Katja, Szabo, Tamas G, Bongiovanni, Laura, Van Den Bos, Hilda, Spierings, Diana Cj, Westendorp, Bart, Stojakovic, Tatjana, Scharnagl, Hubert, Timelthaler, Gerald, Tsuchia, Kaoru, Pinter, Matthias, Foijer, Floris, De Bruin, Alain, Reiberger, Thomas, Rohr-Udilova, Nataliya, Villunger, Andreas
Published in bioRxiv (14.05.2020)
Published in bioRxiv (14.05.2020)
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