Structure-Guided Chemical Optimization of Bicyclic Peptide (Bicycle) Inhibitors of Angiotensin-Converting Enzyme 2
Harman, Maximilian A. J., Stanway, Steven J., Scott, Heather, Demydchuk, Yuliya, Bezerra, Gustavo Arruda, Pellegrino, Simone, Chen, Liuhong, Brear, Paul, Lulla, Aleksei, Hyvönen, Marko, Beswick, Paul J., Skynner, Michael J.
Published in Journal of medicinal chemistry (27.07.2023)
Published in Journal of medicinal chemistry (27.07.2023)
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Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2
Gaynor, Katherine U., Vaysburd, Marina, Harman, Maximilian A. J., Albecka, Anna, Jeffrey, Phillip, Beswick, Paul, Papa, Guido, Chen, Liuhong, Mallery, Donna, McGuinness, Brian, Van Rietschoten, Katerine, Stanway, Steven, Brear, Paul, Lulla, Aleksei, Ciazynska, Katarzyna, Chang, Veronica T., Sharp, Jo, Neary, Megan, Box, Helen, Herriott, Jo, Kijak, Edyta, Tatham, Lee, Bentley, Eleanor G., Sharma, Parul, Kirby, Adam, Han, Ximeng, Stewart, James P., Owen, Andrew, Briggs, John A. G., Hyvönen, Marko, Skynner, Michael J., James, Leo C.
Published in Nature communications (16.06.2023)
Published in Nature communications (16.06.2023)
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DirectMX - One-Step Reconstitution of Membrane Proteins From Crude Cell Membranes Into Salipro Nanoparticles
Lloris-Garcerá, Pilar, Klinter, Stefan, Chen, Liuhong, Skynner, Michael J, Löving, Robin, Frauenfeld, Jens
Published in Frontiers in bioengineering and biotechnology (19.03.2020)
Published in Frontiers in bioengineering and biotechnology (19.03.2020)
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Lipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex
de Haan, Jacco J, Hadfoune, M'hamed, Lubbers, Tim, Hodin, Caroline, Lenaerts, Kaatje, Ito, Akihiko, Verbaeys, Isabelle, Skynner, Michael J, Cailotto, Cathy, van der Vliet, Jan, de Jonge, Wouter J, Greve, Jan-Willem M, Buurman, Wim A
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2013)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2013)
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Inhibition of spleen tyrosine kinase as treatment of postoperative ileus
van Bree, Sjoerd H W, Gomez-Pinilla, Pedro Julian, van de Bovenkamp, Fleur Suzanne, Di Giovangiulio, Martina, Farro, Giovanna, Nemethova, Andrea, Cailotto, Cathy, de Jonge, Wouter J, Lee, Kevin, Ramirez-Molina, Cesar, Lugo, Dave, Skynner, Michael J, Boeckxstaens, Guy E E, Matteoli, Gianluca
Published in Gut (01.11.2013)
Published in Gut (01.11.2013)
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Mutations in Grxcr1 Are The Basis for Inner Ear Dysfunction in the Pirouette Mouse
Odeh, Hana, Hunker, Kristina L., Belyantseva, Inna A., Azaiez, Hela, Avenarius, Matthew R., Zheng, Lili, Peters, Linda M., Gagnon, Leona H., Hagiwara, Nobuko, Skynner, Michael J., Brilliant, Murray H., Allen, Nicholas D., Riazuddin, Saima, Johnson, Kenneth R., Raphael, Yehoash, Najmabadi, Hossein, Friedman, Thomas B., Bartles, James R., Smith, Richard J.H., Kohrman, David C.
Published in American journal of human genetics (12.02.2010)
Published in American journal of human genetics (12.02.2010)
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BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
Rigby, Michael, Bennett, Gavin, Chen, Liuhong, Mudd, Gemma E, Harrison, Helen, Beswick, Paul J, Van Rietschoten, Katerine, Watcham, Sophie M, Scott, Heather S, Brown, Amy N, Park, Peter U, Campbell, Carly, Haines, Eric, Lahdenranta, Johanna, Skynner, Michael J, Jeffrey, Phil, Keen, Nicholas, Lee, Kevin
Published in Molecular cancer therapeutics (02.12.2022)
Published in Molecular cancer therapeutics (02.12.2022)
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Discovery and Characterization of a Bicyclic Peptide (Bicycle) Binder to Thymic Stromal Lymphopoietin
Narjes, Frank, Edfeldt, Fredrik, Petersen, Jens, Öster, Linda, Hamblet, Corinne, Bird, James, Bold, Peter, Rae, Rebecca, Bäck, Elisabeth, Stomilovic, Stina, Zlatoidsky, Pavol, Svensson, Tor, Hidestål, Lotta, Kunalingam, Lavaniya, Shamovsky, Igor, De Maria, Leonardo, Gordon, Euan, Lewis, Richard J., Watcham, Sophie, van Rietschoten, Katerine, Mudd, Gemma E., Harrison, Helen, Chen, Liuhong, Skynner, Michael J.
Published in Journal of medicinal chemistry (08.02.2024)
Published in Journal of medicinal chemistry (08.02.2024)
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Promoter Transgenics Reveal Multiple Gonadotropin-Releasing Hormone-I-Expressing Cell Populations of Different Embryological Origin in Mouse Brain
Skynner, Michael J, Slater, Ruth, Sim, Joan A, Allen, Nick D, Herbison, Allan E
Published in The Journal of neuroscience (15.07.1999)
Published in The Journal of neuroscience (15.07.1999)
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Investigating Penetration and Antimicrobial Activity of Vector-Bicycle Conjugates
Hadjicharalambous, Andreas, Newman, Hector, Lewis, Nick, Rowland, Catherine, Bournakas, Nikolaos, Stanway, Steven J., Dawson, Michael, Skynner, Michael J., Beswick, Paul
Published in ACS infectious diseases (12.07.2024)
Published in ACS infectious diseases (12.07.2024)
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An Assay for Periplasm Entry Advances the Development of Chimeric Peptide Antibiotics
Wagstaff, James M, Balmforth, Matthew, Lewis, Nick, Dods, Rachel, Rowland, Catherine, van Rietschoten, Katerine, Chen, Liuhong, Harrison, Helen, Skynner, Michael J, Dawson, Michael, Ivanova-Berndt, Gabriela, Beswick, Paul
Published in ACS infectious diseases (11.09.2020)
Published in ACS infectious diseases (11.09.2020)
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Tu1629 Spleen Tyrosine Kinase Inhibition Reduces Intestinal Inflammation and Prevents Postoperative Ileus
Matteoli, Gianluca, Farro, Giovanna, Pinilla, Pedro J. Gomez, Di Giovangiulio, Martina, Stakenborg, Nathalie, Nemethova, Andrea, Lee, Kevin, Lugo, David M, Ramirez-Molina, Cesar, Skynner, Michael J, van Bree, Sjoerd H, Boeckxstaens, Guy E
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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Late postnatal reorganization of GABA(A) receptor signalling in native GnRH neurons
Sim, J A, Skynner, M J, Pape, J R, Herbison, A E
Published in The European journal of neuroscience (01.10.2000)
Published in The European journal of neuroscience (01.10.2000)
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Disruption of Ephrin Signaling Associates with Disordered Axophilic Migration of the Gonadotropin-Releasing Hormone Neurons
Gamble, John A, Karunadasa, Delicia K, Pape, Jean-Remi, Skynner, Michael J, Todman, Martin G, Bicknell, R. John, Allen, Jeremy P, Herbison, Allan E
Published in The Journal of neuroscience (23.03.2005)
Published in The Journal of neuroscience (23.03.2005)
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Direct Regulation of Postnatal GnRH Neurons by the Progesterone Derivative Allopregnanolone in the Mouse
Sim, Joan A, Skynner, Michael J, Herbison, Allan E
Published in Endocrinology (Philadelphia) (01.10.2001)
Published in Endocrinology (Philadelphia) (01.10.2001)
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A novel stereocilia defect in sensory hair cells of the deaf mouse mutant Tasmanian devil
Erven, Alexandra, Skynner, Michael J., Okumura, Katsuzumi, Takebayashi, Shin-ichiro, Brown, Steve D. M., Steel, Karen P., Allen, Nicholas D.
Published in The European journal of neuroscience (01.10.2002)
Published in The European journal of neuroscience (01.10.2002)
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