Redesign of a Grignard-Based Active Pharmaceutical Ingredient (API) Batch Synthesis to a Flow Process for the Preparation of Melitracen HCl
Pedersen, Michael J, Skovby, Tommy, Mealy, Michael J, Dam-Johansen, Kim, Kiil, Søren
Published in Organic process research & development (16.02.2018)
Published in Organic process research & development (16.02.2018)
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Journal Article
Active pharmaceutical ingredient (API) production involving continuous processes – A process system engineering (PSE)-assisted design framework
Cervera-Padrell, Albert E., Skovby, Tommy, Kiil, Søren, Gani, Rafiqul, Gernaey, Krist V.
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2012)
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2012)
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Journal Article
Separation of Enantiomers by Continuous Preferential Crystallization: Experimental Realization Using a Coupled Crystallizer Configuration
Chaaban, Joussef Hussein, Dam-Johansen, Kim, Skovby, Tommy, Kiil, Søren
Published in Organic process research & development (16.08.2013)
Published in Organic process research & development (16.08.2013)
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Journal Article
Full-Scale Continuous Mini-Reactor Setup for Heterogeneous Grignard Alkylation of a Pharmaceutical Intermediate
Pedersen, Michael J, Holm, Thomas L, Rahbek, Jesper P, Skovby, Tommy, Mealy, Michael J, Dam-Johansen, Kim, Kiil, Søren
Published in Organic process research & development (20.09.2013)
Published in Organic process research & development (20.09.2013)
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Journal Article
Continuous Spherical Crystallization of Escitalopram Oxalate without Additives
Aprile, Giovanni, Szakter, Kiara, Byrholtz Andersen, Marie, Wu, Hao, Sin, Gürkan, Skovby, Tommy, Dam-Johansen, Kim, Vetter, Thomas
Published in Organic process research & development (16.02.2024)
Published in Organic process research & development (16.02.2024)
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Journal Article
Loop-Configuration for Plug Flow Crystallization Process Development
Aprile, Giovanni, Pandit, Ajinkya V., Albertazzi, Jody, Eren, Ayse, Capellades, Gerard, Thorat, Alpana A., Gamekkanda, Janaka C., Vetter, Thomas, Skovby, Tommy, Sin, Gürkan, Wu, Hao, Dam-Johansen, Kim, Myerson, Allan S.
Published in Crystal growth & design (01.11.2023)
Published in Crystal growth & design (01.11.2023)
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Journal Article
Raman spectroscopy and one‐dimensional convolutional neural network modeling as a real‐time monitoring tool for in vitro transaminase‐catalyzed synthesis of a pharmaceutically relevant amine precursor
Madsen, Julie Østerby, Topalian, Sebastian Olivier Nymann, Jacobsen, Mikkel Fog, Skovby, Tommy, Gernaey, Krist V., Myerson, Allan S., Woodley, John
Published in Biotechnology progress (01.05.2024)
Published in Biotechnology progress (01.05.2024)
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Journal Article
Optimization of Grignard Addition to Esters: Kinetic and Mechanistic Study of Model Phthalide Using Flow Chemistry
Pedersen, Michael J, Born, Stephen, Neuenschwander, Ulrich, Skovby, Tommy, Mealy, Michael J, Kiil, Søren, Dam-Johansen, Kim, Jensen, Klavs F
Published in Industrial & engineering chemistry research (11.04.2018)
Published in Industrial & engineering chemistry research (11.04.2018)
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Journal Article
Continuous Hydrolysis and Liquid–Liquid Phase Separation of an Active Pharmaceutical Ingredient Intermediate Using a Miniscale Hydrophobic Membrane Separator
Cervera-Padrell, Albert E, Morthensen, Sofie T, Lewandowski, Daniel J, Skovby, Tommy, Kiil, Søren, Gernaey, Krist V
Published in Organic process research & development (18.05.2012)
Published in Organic process research & development (18.05.2012)
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Journal Article
Monitoring and Control of a Continuous Grignard Reaction for the Synthesis of an Active Pharmaceutical Ingredient Intermediate Using Inline NIR spectroscopy
Cervera-Padrell, Albert E, Nielsen, Jesper P, Jønch Pedersen, Michael, Müller Christensen, Kim, Mortensen, Asmus R, Skovby, Tommy, Dam-Johansen, Kim, Kiil, Søren, Gernaey, Krist V
Published in Organic process research & development (18.05.2012)
Published in Organic process research & development (18.05.2012)
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Journal Article
A Solvent-Free Base Liberation of a Tertiary Aminoalkyl Halide by Flow Chemistry
Pedersen, Michael J, Skovby, Tommy, Mealy, Michael J, Dam-Johansen, Kim, Kiil, Søren
Published in Organic process research & development (16.12.2016)
Published in Organic process research & development (16.12.2016)
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Journal Article
Implementation of Near-Infrared Spectroscopy for In-Line Monitoring of a Dehydration Reaction in a Tubular Laminar Reactor
Mitic, Aleksandar, Cervera-Padrell, Albert E, Mortensen, Asmus R, Skovby, Tommy, Dam-Johansen, Kim, Javakhishvili, Irakli, Hvilsted, Søren, Gernaey, Krist V
Published in Organic process research & development (19.02.2016)
Published in Organic process research & development (19.02.2016)
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Journal Article
Design and operation of a filter reactor for continuous production of a selected pharmaceutical intermediate
Christensen, Kim Müller, Pedersen, Michael Jønch, Dam-Johansen, Kim, Holm, Thomas Lønberg, Skovby, Tommy, Kiil, Søren
Published in Chemical engineering science (26.03.2012)
Published in Chemical engineering science (26.03.2012)
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Journal Article
Apparatus and method for isolation and/or preparation of particles
Sogaard, Steen, Mortensen, Asmus Ringlebjerg, Gad, Jens Andersen, Skovby, Tommy Carsten Lund
Year of Publication 10.01.2023
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Year of Publication 10.01.2023
Patent
APPARATUS AND METHOD FOR ISOLATION AND/OR PREPARATION OF PARTICLES
Sogaard, Steen, Mortensen, Asmus Ringlebjerg, Gad, Jens Andersen, Skovby, Tommy Carsten Lund
Year of Publication 30.09.2021
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Year of Publication 30.09.2021
Patent
APPARATUS AND METHOD FOR ISOLATION AND/OR PREPARATION OF PARTICLES
SKOVBY, Tommy, Carsten, Lund, GAD, Jens, Andersen, SØGAARD, Steen, MORTENSEN, Asmus, Ringlebjerg
Year of Publication 12.02.2020
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Year of Publication 12.02.2020
Patent