Bone marrow biopsy in low‐risk monoclonal gammopathy of undetermined significance reveals a novel smoldering multiple myeloma risk group
Bustoros, Mark, Kastritis, Efstathios, Sklavenitis‐Pistofidis, Romanos, Liu, Chia‐Jen, Hornburg, Kalvis, Kanellias, Nikolaos, Kim, Geon, Liu, David, Gavriatopoulou, Maria, Marinac, Catherine R., Roussou, Maria, Migkou, Magdalini, Noonan, Kimberly, Reyes, Kaitlen, Rivotto, Bradley, Neuse, Carl Jannes, Ziogas, Dimitrios C., Laubach, Jacob, Terpos, Evangelos, Anderson, Kenneth C., Richardson, Paul G., Ghobrial, Irene M., Dimopoulos, Meletios A.
Published in American journal of hematology (01.05.2019)
Published in American journal of hematology (01.05.2019)
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Journal Article
Bone marrow niche in multiple myeloma and its precursor states
Sklavenitis‐Pistofidis, Romanos, Bustoros, Mark, Ghobrial, Irene M.
Published in HemaSphere (01.06.2019)
Published in HemaSphere (01.06.2019)
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Journal Article
Single-cell RNA sequencing: one step closer to the clinic
Sklavenitis-Pistofidis, Romanos, Getz, Gad, Ghobrial, Irene
Published in Nature medicine (01.03.2021)
Published in Nature medicine (01.03.2021)
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Journal Article
Single-cell profiling of tumour evolution in multiple myeloma — opportunities for precision medicine
Dutta, Ankit K., Alberge, Jean-Baptiste, Sklavenitis-Pistofidis, Romanos, Lightbody, Elizabeth D., Getz, Gad, Ghobrial, Irene M.
Published in Nature reviews. Clinical oncology (01.04.2022)
Published in Nature reviews. Clinical oncology (01.04.2022)
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Journal Article
Genomic Landscape of Waldenström Macroglobulinemia and Its Impact on Treatment Strategies
Treon, Steven P, Xu, Lian, Guerrera, Maria Luisa, Jimenez, Cristina, Hunter, Zachary R, Liu, Xia, Demos, Maria, Gustine, Joshua, Chan, Gloria, Munshi, Manit, Tsakmaklis, Nicholas, Chen, Jiaji G, Kofides, Amanda, Sklavenitis-Pistofidis, Romanos, Bustoros, Mark, Keezer, Andrew, Meid, Kirsten, Patterson, Christopher J, Sacco, Antonio, Roccaro, Aldo, Branagan, Andrew R, Yang, Guang, Ghobrial, Irene M, Castillo, Jorge J
Published in Journal of clinical oncology (10.04.2020)
Published in Journal of clinical oncology (10.04.2020)
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Journal Article
Inflammatory stromal cells in the myeloma microenvironment
Sklavenitis-Pistofidis, Romanos, Haradhvala, Nicholas J., Getz, Gad, Ghobrial, Irene M.
Published in Nature immunology (01.06.2021)
Published in Nature immunology (01.06.2021)
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Journal Article
Progression Risk Stratification of Asymptomatic Waldenström Macroglobulinemia
Bustoros, Mark, Sklavenitis-Pistofidis, Romanos, Kapoor, Prashant, Liu, Chia-Jen, Kastritis, Efstathios, Zanwar, Saurabh, Fell, Geoffrey, Abeykoon, Jithma P, Hornburg, Kalvis, Neuse, Carl Jannes, Marinac, Catherine R, Liu, David, Soiffer, Jenny, Gavriatopoulou, Maria, Boehner, Cody, Cappuccio, Joseph M, Dumke, Henry, Reyes, Kaitlen, Soiffer, Robert J, Kyle, Robert A, Treon, Steven P, Castillo, Jorge J, Dimopoulos, Meletios A, Ansell, Stephen M, Trippa, Lorenzo, Ghobrial, Irene M
Published in Journal of clinical oncology (01.06.2019)
Published in Journal of clinical oncology (01.06.2019)
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Journal Article
Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis
Boiarsky, Rebecca, Haradhvala, Nicholas J., Alberge, Jean-Baptiste, Sklavenitis-Pistofidis, Romanos, Mouhieddine, Tarek H., Zavidij, Oksana, Shih, Ming-Chieh, Firer, Danielle, Miller, Mendy, El-Khoury, Habib, Anand, Shankara K., Aguet, François, Sontag, David, Ghobrial, Irene M., Getz, Gad
Published in Nature communications (17.11.2022)
Published in Nature communications (17.11.2022)
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Journal Article
Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression
Kawano, Yawara, Zavidij, Oksana, Park, Jihye, Moschetta, Michele, Kokubun, Katsutoshi, Mouhieddine, Tarek H, Manier, Salomon, Mishima, Yuji, Murakami, Naoka, Bustoros, Mark, Pistofidis, Romanos Sklavenitis, Reidy, Mairead, Shen, Yu J, Rahmat, Mahshid, Lukyanchykov, Pavlo, Karreci, Esilida Sula, Tsukamoto, Shokichi, Shi, Jiantao, Takagi, Satoshi, Huynh, Daisy, Sacco, Antonio, Tai, Yu-Tzu, Chesi, Marta, Bergsagel, P Leif, Roccaro, Aldo M, Azzi, Jamil, Ghobrial, Irene M
Published in The Journal of clinical investigation (01.06.2018)
Published in The Journal of clinical investigation (01.06.2018)
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Journal Article
Multiple Myeloma With Amplification of Chr1q: Therapeutic Opportunity and Challenges
Sklavenitis-Pistofidis, Romanos, Getz, Gad, Ghobrial, Irene, Papaioannou, Maria
Published in Frontiers in oncology (14.07.2022)
Published in Frontiers in oncology (14.07.2022)
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Journal Article
Acute lymphoblastic leukemia as a clonally unrelated second primary malignancy after multiple myeloma
Aldoss, Ibrahim, Capelletti, Marzia, Park, Jihye, Pistofidis, Romanos Sklavenitis, Pillai, Raju, Stiller, Tracey, Sanchez, James F., Forman, Stephen J., Ghobrial, Irene M., Krishnan, Amrita
Published in Leukemia (01.01.2019)
Published in Leukemia (01.01.2019)
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Journal Article
Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes
Bustoros, Mark, Anand, Shankara, Sklavenitis-Pistofidis, Romanos, Redd, Robert, Boyle, Eileen M., Zhitomirsky, Benny, Dunford, Andrew J., Tai, Yu-Tzu, Chavda, Selina J., Boehner, Cody, Neuse, Carl Jannes, Rahmat, Mahshid, Dutta, Ankit, Casneuf, Tineke, Verona, Raluca, Kastritis, Efstathis, Trippa, Lorenzo, Stewart, Chip, Walker, Brian A., Davies, Faith E., Dimopoulos, Meletios-Athanasios, Bergsagel, P. Leif, Yong, Kwee, Morgan, Gareth J., Aguet, François, Getz, Gad, Ghobrial, Irene M.
Published in Nature communications (15.06.2022)
Published in Nature communications (15.06.2022)
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Journal Article
Profiling of circulating exosomal miRNAs in patients with Waldenström Macroglobulinemia
Bouyssou, Juliette M, Liu, Chia-Jen, Bustoros, Mark, Sklavenitis-Pistofidis, Romanos, Aljawai, Yosra, Manier, Salomon, Yosef, Amir, Sacco, Antonio, Kokubun, Katsutoshi, Tsukamoto, Shokichi, Perilla Glen, Adriana, Huynh, Daisy, Castillo, Jorge J, Treon, Steven P, Leblond, Véronique, Hermine, Olivier, Roccaro, Aldo M, Ghobrial, Irene M, Capelletti, Marzia
Published in PloS one (04.10.2018)
Published in PloS one (04.10.2018)
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Journal Article
MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma
Hasan Bou Issa, Lama, Fléchon, Léa, Laine, William, Ouelkdite, Aicha, Gaggero, Silvia, Cozzani, Adeline, Tilmont, Remi, Chauvet, Paul, Gower, Nicolas, Sklavenitis-Pistofidis, Romanos, Brinster, Carine, Thuru, Xavier, Touil, Yasmine, Quesnel, Bruno, Mitra, Suman, Ghobrial, Irene M., Kluza, Jérôme, Manier, Salomon
Published in iScience (19.04.2024)
Published in iScience (19.04.2024)
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Journal Article
Mass cytometry staining for human bone marrow clinical samples
Hallisey, Margaret, Dennis, Jenna, Abrecht, Charlotte, Pistofidis, Romanos Sklavenitis, Schork, Abigail N., Lightbody, Elizabeth D., Heilpern-Mallory, Daniel, Severgnini, Mariano, Ghobrial, Irene M., Hodi, F. Stephen, Baginska, Joanna
Published in STAR protocols (18.03.2022)
Published in STAR protocols (18.03.2022)
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Journal Article
Diagnostic TR-FRET assays for detection of antibodies in patient samples
Yue, Hong, Nowak, Radosław P., Overwijn, Daan, Payne, N. Connor, Fischinger, Stephanie, Atyeo, Caroline, Lam, Evan C., St. Denis, Kerri, Brais, Lauren K., Konishi, Yoshinobu, Sklavenitis-Pistofidis, Romanos, Baden, Lindsey R., Nilles, Eric J., Karlson, Elizabeth W., Yu, Xu G., Li, Jonathan Z., Woolley, Ann E., Ghobrial, Irene M., Meyerhardt, Jeffrey A., Balazs, Alejandro B., Alter, Galit, Mazitschek, Ralph, Fischer, Eric S.
Published in Cell reports methods (27.03.2023)
Published in Cell reports methods (27.03.2023)
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Journal Article
Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression
Bustoros, Mark, Sklavenitis-Pistofidis, Romanos, Park, Jihye, Redd, Robert, Zhitomirsky, Benny, Dunford, Andrew J, Salem, Karma, Tai, Yu-Tzu, Anand, Shankara, Mouhieddine, Tarek H, Chavda, Selina J, Boehner, Cody, Elagina, Liudmila, Neuse, Carl Jannes, Cha, Justin, Rahmat, Mahshid, Taylor-Weiner, Amaro, Van Allen, Eliezer, Kumar, Shaji, Kastritis, Efstathis, Leshchiner, Ignaty, Morgan, Elizabeth A, Laubach, Jacob, Casneuf, Tineke, Richardson, Paul, Munshi, Nikhil C, Anderson, Kenneth C, Trippa, Lorenzo, Aguet, François, Stewart, Chip, Dimopoulos, Meletios-Athanasios, Yong, Kwee, Bergsagel, P Leif, Manier, Salomon, Getz, Gad, Ghobrial, Irene M
Published in Journal of clinical oncology (20.07.2020)
Published in Journal of clinical oncology (20.07.2020)
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Journal Article
A Phase Ib/II Trial of the First-in-Class Anti-CXCR4 Antibody Ulocuplumab in Combination with Lenalidomide or Bortezomib Plus Dexamethasone in Relapsed Multiple Myeloma
Ghobrial, Irene M, Liu, Chia-Jen, Redd, Robert A, Perez, Raymond P, Baz, Rachid, Zavidij, Oksana, Sklavenitis-Pistofidis, Romanos, Richardson, Paul G, Anderson, Kenneth C, Laubach, Jacob, Henrick, Patrick, Savell, Alexandra, Reyes, Kaitlen, Hornburg, Kalvis, Chuma, Stacey, Sabbatini, Peter, Robbins, Michael D, Becker, Pamela S
Published in Clinical cancer research (15.01.2020)
Published in Clinical cancer research (15.01.2020)
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Journal Article
Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
Kazandjian, Dickran, Diamond, Benjamin, Papadimitriou, Marios, Hill, Elizabeth, Sklavenitis-Pistofidis, Romanos, Ziccheddu, Bachisio, Blaney, Patrick, Chojnacka, Monika, Durante, Michael, Maclachlan, Kylee, Young, Ryan, Usmani, Saad, Davies, Faith, Getz, Gad, Ghobrial, Irene, Korde, Neha, Morgan, Gareth, Maura, Francesco, Landgren, Ola
Published in Clinical cancer research (01.10.2024)
Published in Clinical cancer research (01.10.2024)
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Journal Article
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant
Mouhieddine, Tarek H., Sperling, Adam S., Redd, Robert, Park, Jihye, Leventhal, Matthew, Gibson, Christopher J., Manier, Salomon, Nassar, Amin H., Capelletti, Marzia, Huynh, Daisy, Bustoros, Mark, Sklavenitis-Pistofidis, Romanos, Tahri, Sabrin, Hornburg, Kalvis, Dumke, Henry, Itani, Muhieddine M., Boehner, Cody J., Liu, Chia-Jen, AlDubayan, Saud H., Reardon, Brendan, Van Allen, Eliezer M., Keats, Jonathan J., Stewart, Chip, Mehr, Shaadi, Auclair, Daniel, Schlossman, Robert L., Munshi, Nikhil C., Anderson, Kenneth C., Steensma, David P., Laubach, Jacob P., Richardson, Paul G., Ritz, Jerome, Ebert, Benjamin L., Soiffer, Robert J., Trippa, Lorenzo, Getz, Gad, Neuberg, Donna S., Ghobrial, Irene M.
Published in Nature communications (12.06.2020)
Published in Nature communications (12.06.2020)
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Journal Article