Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes[S]
Nilsson, Inga, Lee, Sheng Y., Sawyer, William S., Baxter Rath, Christopher M., Lapointe, Guillaume, Six, David A.
Published in Journal of lipid research (01.06.2020)
Published in Journal of lipid research (01.06.2020)
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Journal Article
Discovery of new biosynthetic pathways: the lipid A story
Raetz, Christian R.H., Guan, Ziqiang, Ingram, Brian O., Six, David A., Song, Feng, Wang, Xiaoyuan, Zhao, Jinshi
Published in Journal of lipid research (01.04.2009)
Published in Journal of lipid research (01.04.2009)
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Journal Article
Phosphate Groups of Lipid A Are Essential for Salmonella enterica Serovar Typhimurium Virulence and Affect Innate and Adaptive Immunity
Kong, Qingke, Six, David A, Liu, Qing, Gu, Lillian, Wang, Shifeng, Alamuri, Praveen, Raetz, Christian R H, Curtiss, 3rd, Roy
Published in Infection and Immunity (01.09.2012)
Published in Infection and Immunity (01.09.2012)
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Journal Article
A pathway-directed positive growth restoration assay to facilitate the discovery of lipid A and fatty acid biosynthesis inhibitors in Acinetobacter baumannii
Richie, Daryl L, Wang, Lisha, Chan, Helen, De Pascale, Gianfranco, Six, David A, Wei, Jun-Rong, Dean, Charles R
Published in PloS one (05.03.2018)
Published in PloS one (05.03.2018)
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Journal Article
Palmitoylation State Impacts Induction of Innate and Acquired Immunity by the Salmonella enterica Serovar Typhimurium msbB Mutant
Kong, Qingke, Six, David A, Liu, Qing, Gu, Lillian, Roland, Kenneth L, Raetz, Christian R H, Curtiss, 3rd, Roy
Published in Infection and Immunity (01.12.2011)
Published in Infection and Immunity (01.12.2011)
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Journal Article
In Vivo Phospholipase Activity of the Pseudomonas aeruginosa Cytotoxin ExoU and Protection of Mammalian Cells with Phospholipase A2 Inhibitors
Phillips, Rebecca M., Six, David A., Dennis, Edward A., Ghosh, Partho
Published in The Journal of biological chemistry (17.10.2003)
Published in The Journal of biological chemistry (17.10.2003)
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Journal Article
Deletion of the β-Acetoacetyl Synthase FabY in Pseudomonas aeruginosa Induces Hypoacylation of Lipopolysaccharide and Increases Antimicrobial Susceptibility
SIX, David A, YANQIU YUAN, LEEDS, Jennifer A, MEREDITH, Timothy C
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
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Journal Article
Pathogenicity of Yersinia pestis Synthesis of 1-Dephosphorylated Lipid A
Sun, Wei, Six, David A, Reynolds, C Michael, Chung, Hak Suk, Raetz, Christian R H, Curtiss, 3rd, Roy
Published in Infection and Immunity (01.04.2013)
Published in Infection and Immunity (01.04.2013)
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Journal Article
Iron Acquisition Systems of Gram-negative Bacterial Pathogens Define TonB-Dependent Pathways to Novel Antibiotics
Klebba, Phillip E, Newton, Salete M. C, Six, David A, Kumar, Ashish, Yang, Taihao, Nairn, Brittany L, Munger, Colton, Chakravorty, Somnath
Published in Chemical reviews (12.05.2021)
Published in Chemical reviews (12.05.2021)
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Journal Article
Lipopolysaccharide (LPS) inner-core phosphates are required for complete LPS synthesis and transport to the outer membrane in Pseudomonas aeruginosa PAO1
Delucia, Angela M, Six, David A, Caughlan, Ruth E, Gee, Patricia, Hunt, Ian, Lam, Joseph S, Dean, Charles R
Published in mBio (2011)
Published in mBio (2011)
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Journal Article
Purification and Characterization of the Lipid A 1-Phosphatase LpxE of Rhizobium leguminosarum
Karbarz, Mark J., Six, David A., Raetz, Christian R.H.
Published in The Journal of biological chemistry (02.01.2009)
Published in The Journal of biological chemistry (02.01.2009)
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Journal Article
Advances and challenges in bacterial compound accumulation assays for drug discovery
Six, David A, Krucker, Thomas, Leeds, Jennifer A
Published in Current opinion in chemical biology (01.06.2018)
Published in Current opinion in chemical biology (01.06.2018)
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Journal Article
Molecular characterization and verification of azido-3,8-dideoxy-d-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide
Nilsson, Inga, Grove, Kerri, Dovala, Dustin, Uehara, Tsuyoshi, Lapointe, Guillaume, Six, David A.
Published in The Journal of biological chemistry (01.12.2017)
Published in The Journal of biological chemistry (01.12.2017)
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Journal Article
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa
Hamrick, Jodie C, Docquier, Jean-Denis, Uehara, Tsuyoshi, Myers, Cullen L, Six, David A, Chatwin, Cassandra L, John, Kaitlyn J, Vernacchio, Salvador F, Cusick, Susan M, Trout, Robert E L, Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Mangani, Stefano, Liu, Bin, Jackson, Randy W, Moeck, Greg, Xerri, Luigi, Burns, Christopher J, Pevear, Daniel C, Daigle, Denis M
Published in Antimicrobial agents and chemotherapy (21.02.2020)
Published in Antimicrobial agents and chemotherapy (21.02.2020)
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The sialic acid transporter NanT is necessary and sufficient for uptake of 3‐deoxy‐d‐manno‐oct‐2‐ulosonic acid (Kdo) and its azido analog in Escherichia coli
Nilsson, Inga, Prathapam, Ramadevi, Grove, Kerri, Lapointe, Guillaume, Six, David A.
Published in Molecular microbiology (01.10.2018)
Published in Molecular microbiology (01.10.2018)
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Journal Article
In Vitro Activity of Cefepime-Taniborbactam and Comparators against Clinical Isolates of Gram-Negative Bacilli from 2018 to 2020: Results from the Global Evaluation of Antimicrobial Resistance via Surveillance (GEARS) Program
Karlowsky, James A, Hackel, Meredith A, Wise, Mark G, Six, David A, Uehara, Tsuyoshi, Daigle, Denis M, Cusick, Susan M, Pevear, Daniel C, Moeck, Greg, Sahm, Daniel F
Published in Antimicrobial agents and chemotherapy (24.01.2023)
Published in Antimicrobial agents and chemotherapy (24.01.2023)
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